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Chemistry World March 2, 2011 Sarah Corcoran |
Natural products go with the flow Technology that could bring flow chemistry into the domain of complex natural product synthesis has been developed by UK scientists. |
Chemistry World January 21, 2013 Michael Parkin |
Flow synthesis for anticancer drug UK chemists have used a combination of flow chemistry methods with solid-supported scavengers and reagents to synthesize the active pharmaceutical ingredient, imatinib, of the anticancer drug Gleevec. |
Chemistry World November 2007 Derek Lowe |
Column: In the Pipeline Chemists are finally going with the flow. |
Chemistry World October 22, 2013 Marie Cote |
Oliver Kappe: Freedom to explore Oliver Kappe is professor of chemistry at the University of Graz in Austria. Research in the Kappe group focuses on enabling technologies for synthesis, including microwave and continuous flow methods. |
Chemistry World January 13, 2011 Sarah Corcoran |
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. |
Chemistry World May 25, 2007 Richard Van Noorden |
Keeping it Green Some chemistry enthusiastically labeled as green may be nothing of the kind, warn researchers who worry that mediocre -- if well-meaning -- science is damaging their subject. |
Chemistry World July 9, 2008 James Mitchell Crow |
Pharma goes green to cut costs The pharmaceutical industry's current drive to curb spending is helping to speed the adoption of green chemistry, say experts in the industry. |
Chemistry World March 22, 2012 Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World September 2008 Derek Lowe |
Column: In the pipeline The author remembers leaving the ivory towers of academe to trade 'unusual and beautiful' for 'useful' |
Chemistry World April 2007 Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
Chemistry World January 17, 2014 Katia Moskvitch |
Life may have begun in a tiny water droplet Chemical reactions run much faster and more efficiently when they take place in tiny droplets rather than in freestanding water -- such as a puddle or a lake, say researchers. |
Chemistry World April 17, 2013 Mark Peplow |
Sanofi launches malaria drug production On 11 April, the Paris-based pharmaceutical company Sanofi officially launched a new production facility in Garessio, Italy, to make artemisinin -- the precursor to artemisinin-based combination therapies, the most effective drugs against the deadliest malaria parasite. |
Chemistry World June 19, 2013 John Hayward |
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. |
Chemistry World March 2011 |
Microwave chemistry - green or not? Microwave-assisted chemistry might not deserve its environmentally friendly reputation, argues Jonathan Moseley |
Chemistry World August 2007 Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Reactive Reports Issue 67 David Bradley |
Multichannel Microchemical Factory The microchemical factory approach offers a safer and scaleable approach to producing materials from the very smallest quantities to the largest bulk. |
Chemistry World September 17, 2007 |
Uk Pharma Shifts Manufacturing Overseas Drug firm AstraZeneca has today reiterated that it will outsource drug manufacturing. |
Chemistry World March 21, 2007 Alison Stoddart |
Synthesis Strategy Offers no Protection A radically different approach to constructing complex molecules could help to tap the pharmaceutical potential of natural products. |
Chemistry World January 11, 2013 Marie Cote |
Following her passion Veronique Gouverneur is professor of chemistry at the University of Oxford, UK. She investigates fluorine chemistry and is working on developing novel synthetic methodologies for the preparation of fluorinated targets. |
Chemistry World June 27, 2013 Rachel Cooper |
Self-contained chemical synthesis Scientists in the UK have used reactors made on a 3D printer to complete a three stage organic synthesis. |
Chemistry World October 2007 Derek Lowe |
In the Pipeline One of the biggest areas of chemical research these days is in catalytic processes. It's one of the places we can really improve our processes, especially when you count the waste stream (as you should) as part of the total energy bill. |
Chemistry World July 2006 |
New on the Market The invisible becomes visible... 24 reactions at the same time... Evaporator for medicinal chemistry... Dry vacuum... World first in magnets... Centrifuging made easy... |
Chemistry World February 2009 Richard Van Noorden |
Editorial: Survival of the fattest The results of the UK's 2008 research assessment exercise, a national audit of university research quality, were announced late last year, and they were good news for the country's chemistry departments. |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. |
Chemistry World August 16, 2009 Tom Bond |
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. |
Chemistry World August 10, 2007 Richard Van Noorden |
Azadirachtin Sees First Total Synthesis A complex natural product has finally succumbed to its first total synthesis after 22 years of attempts by eminent organic chemists. |
Chemistry World August 6, 2014 Simon Hadlington |
3D printed reactionware hots up UK researchers have shown that it is possible to carry out a range of hydrothermal chemical syntheses in sealed reactors made from 3D printed polypropylene. |
Reactive Reports Issue 60 David Bradley |
Mark Leach Interview with the owner of Meta-Synthesis, a company aimed to reveal the inner secrets of chemistry to as wide an audience as possible. |
Chemistry World October 2009 |
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions |
Chemistry World November 3, 2008 Simon Hadlington |
Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple? |
Chemistry World October 12, 2011 Joanne Thomson |
Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry. |
Reactive Reports September 2007 David Bradley |
Insecticidal Synthesis The efforts of 40 PhD chemistry students and many others have found a way to construct azadirachtin -- a natural insecticide from the neem tree -- in a total synthesis of 64 individual chemical reaction steps. |
Chemistry World November 11, 2015 Aurora Walshe |
H 2-free route to actinide hydrides Scientists in the US have shown that phenylsilane is a safer and more convenient replacement for hydrogen gas when synthesizing uranium and thorium hydrides. |
Chemistry World June 2010 Paul Docherty |
Column: Totally Synthetic Although its chemistry is mature and varied, my use of silicon reagents in my synthetic forays has been limited to a somewhat clumsy use of hydroxyl protecting groups. |
Chemistry World May 8, 2014 |
Mandelalide A The recent synthesis of the proposed structure of mandelalide A is a good example of a well-designed route that seamlessly integrates some cutting-edge chemistry. |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. |
Reactive Reports December 2006 David Bradley |
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. |
Chemistry World March 13, 2006 |
Thriving Chemistry Department Faces Closure Anger surrounded the announcement that from October 2007 the chemistry department at Sussex University, UK, will make way for a department of chemical biology. |
Chemistry World October 1, 2012 Paul Docherty |
Prostaglandin F2I There's been no shortage of grant funding for synthetic chemistry of the prostaglandins, keeping some of the finest minds in organic chemistry engaged over the last five decades. |
Chemistry World February 2008 Dylan Stiles |
Column: Bench Monkey Cast a skeptical eye over new ideas in chemistry. |
Chemistry World October 1, 2013 Eleanor Merritt |
New software for creating green solvents Scientists in France have developed a computer-assisted organic synthesis program to design sustainable solvents from bio-based building blocks. |
Chemistry World January 25, 2013 Derek Lowe |
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? |
Chemistry World March 19, 2009 Manisha Lalloo |
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings |
Reactive Reports Issue 45 |
Star Picks Chemistry Web sites: Chemists Celebrate Earth Day: Resources... Doing Chemistry... Chemistry Question... |
Chemistry World April 25, 2014 Derek Lowe |
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. |
Chemistry World August 1, 2013 James Urquhart |
Total synthesis outshines biotech route to anticancer drug US scientists have developed the first efficient and scalable route for the total synthesis of ingenol -- a plant-derived diterpenoid used to treat precancerous skin legions. |
Chemistry World January 2012 |
A new year and a new dawn As the International Year of Chemistry drew to a close last year, we were delighted to see the future of chemistry in the UK being bolstered with two universities planning to reopen their chemistry departments |
Information Today July 2, 2015 |
Thieme Chemistry Updates Synthetic Organic Chemistry Resource Thieme Chemistry rolled out the newest release of its Science of Synthesis 4.1, which is a full-text resource for methods and experimental procedures in synthetic organic chemistry. |
Chemistry World January 2009 Richard Van Noorden |
Editorial: Sustainable connection The interface between chemistry and engineering is more important than ever. |
Chemistry World June 2007 |
Student Book Reviews Chemistry for CSI Fans... At the Heart of Molecular Biology... A Broad Vista of Chemistry...Rings Are Not Just for Carbons... etc. |