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Bio-IT World
February 18, 2004
Just Bead It MPSS can help address the limitations of microarrays. mark for My Articles similar articles
Chemistry World
December 20, 2010
Jennifer Newton
Frozen assets in biobanks Scientists from Sweden have devised a technique that extracts both DNA and RNA from frozen tissue in a bid to improve large-scale extractions from samples stored in biobanks, which could aid cancer research. mark for My Articles similar articles
Chemistry World
January 31, 2008
John Bonner
RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process. mark for My Articles similar articles
Chemistry World
January 12, 2015
Emma Stoye
Protein mutant libraries to probe diseases' genetic link quickly and cheaply Researchers in the US have developed a faster and less costly way to investigate the effects of genetic mutations on proteins, which should offer new insights into hereditary diseases. mark for My Articles similar articles
HHMI Bulletin
Aug 2011
Cassandra Willyard
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. mark for My Articles similar articles
HHMI Bulletin
May 2012
Sarah C. P. Williams
Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases. mark for My Articles similar articles
Chemistry World
November 27, 2007
James Mitchell Crow
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. mark for My Articles similar articles
Chemistry World
January 11, 2008
John Bonner
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. mark for My Articles similar articles
Managed Care
November 2003
Thomas Morrow
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. mark for My Articles similar articles
Chemistry World
October 31, 2007
John Bonner
Brain's Wiring Seen in Technicolor Researchers in the US have developed a technique that could allow neurologists to draw a detailed wiring plan of the mammalian brain by inserting genes coding for fluorescent proteins into transgenic mice. mark for My Articles similar articles
Salon.com
May 1, 2000
Arthur Allen
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. mark for My Articles similar articles
IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
Chemistry World
January 28, 2011
David Barden
Chips make short work of RNA synthesis Chinese scientists have developed a much easier way to make the short strands of RNA that are an essential tool in understanding what genes do. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Sarah C.P. Williams
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. mark for My Articles similar articles
Bio-IT World
February 18, 2004
Pathology Goes Molecular New technologies are enabling clinical diagnostic laboratories to pave the way toward more personalized cancer therapies mark for My Articles similar articles
Scientific American
June 2005
JR Minkel
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. mark for My Articles similar articles
Bio-IT World
February 18, 2004
Proteomics Goes Cellular Tissue microarrays save big on sample material and reagents. But more importantly, this new high-throughput technology is helping save the lives of cancer patients mark for My Articles similar articles
Chemistry World
April 28, 2008
Victoria Gill
Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer. mark for My Articles similar articles
Chemistry World
February 24, 2010
James Urquhart
Buckyball-based gene delivery Japanese researchers have demonstrated effective gene delivery in mice using carbon buckyballs. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Skin Sense An early question about aging skin led to answers on how cells code for their location. mark for My Articles similar articles
Chemistry World
February 2012
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball mark for My Articles similar articles
Bio-IT World
September 11, 2003
Kevin Davies
Chipping Away at Cancer In Vivo, In Situ Two studies probe new applications of DNA microarrays, revealing new insights into the pathogenesis and pharmacogenomics of cancer. mark for My Articles similar articles
Technology Research News
October 6, 2004
Chip spots DNA electrochemically A microelectrochemical method of reading DNA chips could be used in portable detectors. It could be use practically in two to five years, according to the researchers. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows. mark for My Articles similar articles
Chemistry World
April 25, 2006
Jon Evans
DNA Sequencing Reaches the Space Age The smallest ever DNA sequencer, only 10cm in diameter, comprises a complex network of microscopic pumps, valves, heaters and electrophoresis channels, many of which were initially developed for use in a device to detect life on Mars. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Sarah C.P. Williams
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. mark for My Articles similar articles
Chemistry World
October 2, 2006
Bea Perks
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. mark for My Articles similar articles
Chemistry World
November 16, 2006
Simon Hadlington
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. mark for My Articles similar articles
Chemistry World
January 25, 2010
Hayley Birch
Stabilising RNAs enhances gene silencing in tumours South Korean scientists have found a way to stabilise therapeutic RNA molecules, using chemical modifications, so that they can be more smoothly trafficked into cells. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Donna Mendrick
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. mark for My Articles similar articles
HHMI Bulletin
February 2012
Sarah C.P. Williams
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Rotem Sorek
Alternative Splicing: Listen to the Mouse The completed mouse genome may help to finally pin down the size of the transcriptome. mark for My Articles similar articles
Popular Mechanics
September 25, 2009
Erin McCarthy
Fringe's Human Mutant Not Possible, Says Expert We won't ever have to worry about Fringe's part-mole-rat, part-scorpion, part-human mutant in real life because it's not within the realm of possibility. mark for My Articles similar articles
Technology Research News
June 16, 2004
Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA. mark for My Articles similar articles
Chemistry World
July 16, 2009
James Urquhart
New DNA technique sheds light on ancient populations A new sequencing technique that is cheaper and less wasteful has been used to decode and analyse the mitochondrial genomes of five Neanderthal individuals. mark for My Articles similar articles
Scientific American
June 2009
Melinda Wenner
Genetic Copy Variations and Disease A new sense for how variable numbers of genes cause disease. mark for My Articles similar articles
The Motley Fool
September 28, 2007
Brian Orelli
RNAi Doesn't Kill Mice After All From Merck, to AstraZeneca, to Novartis, big pharma continues to pump hundreds of millions of dollars into unproven RNAi technology. Investors, take note. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Robert M. Frederickson
Protein Chemistry Surfaces Protein chips seek to do for protein expression profiling what DNA chips did for RNA expression. mark for My Articles similar articles
Chemistry World
November 12, 2009
Hayley Birch
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
Chemistry World
September 23, 2009
Simon Hadlington
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. mark for My Articles similar articles
Bio-IT World
June 17, 2004
Michael A. Goldman
A Hip Approach to Gene Hunting IntegraGen defines the genetic blueprint of complex human diseases and delivers validated disease markers and therapeutic targets for a better diagnosis and a causal treatment of common diseases, based on its unique genomic analysis expertise. mark for My Articles similar articles
Bio-IT World
September 2006
Robert M. Frederickson
Assays and Knowledgebases for Genomic Analysis An important aspect of any genomic analysis -- whether expression profiling or analysis of DNA-binding elements as above -- is the integration of the data with existing knowledge. mark for My Articles similar articles
Chemistry World
April 20, 2009
James Urquhart
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. mark for My Articles similar articles
Scientific American
September 2008
Melinda Wenner
Rethinking the Wrinkling: Key Genes Cause Aging Key genes, rather than cell and DNA damage, as causes of aging. mark for My Articles similar articles
Chemistry World
January 30, 2014
Anthony King
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Dave Mosher
A New PACE for Laboratory Evolution Researchers have found a way to accelerate evolution of molecules by harnessing viruses. mark for My Articles similar articles
Chemistry World
May 16, 2007
Tom Westgate
DNA Photography It is a technology that is fast disappearing in the digital age. But black and white photography is more than an archaic art-form to a team of German chemists who have used it as the basis for a simple method of detecting labeled DNA molecules at attomole levels. mark for My Articles similar articles
Technology Research News
September 24, 2003
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. mark for My Articles similar articles
PC Magazine
July 13, 2005
John R. Quain
DNA Printing Press A group of scientists believes it has an inexpensive nanoprinting technique that could lead to the mass production of DNA-based chips that could revolutionize disease detection. mark for My Articles similar articles