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Chemistry World October 14, 2011 James Mitchell Crow |
Twist in the tale to improve gene therapy New insights into the physical properties of different forms of DNA could help to improve gene therapy, chemists in Spain and India say. |
Chemistry World March 30, 2006 Helen Carmichael |
Gene Therapists Swarm Round Honeycomb Lipid Researchers have synthesised a lipid molecule they say shows real promise in gene therapy. The lipid forms a novel honeycomb complex that the researchers claim is tailored to non-viral DNA delivery. |
Scientific American July 2008 Christine Soares |
Looking at Yesterday's Genes for Tomorrow's Cures Resurrected "jumping gene" could deliver DNA. |
HHMI Bulletin Aug 2011 |
Seeing is Believing Today, researchers are finding clever ways to deliver long-lasting, healthy genes without triggering a serious immune response. |
Chemistry World April 28, 2008 Victoria Gill |
Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer. |
The Motley Fool July 30, 2007 Brian Orelli |
Another Blow to Gene Therapy The FDA shuts down a clinical trial, tripping up Targeted Genetics and possibly its competitors. A subject in the trial of their gene therapy arthritis medication died shortly after taking the drug. |
Chemistry World September 26, 2006 Fiona Case |
Synchronised Delivery for DNA and Drugs Polymer capsules that can simultaneously deliver drug molecules and DNA into a cell could boost the power of cancer treatments. |
Wired September 2002 Amanda Griscom |
Take These Genes and Call Me in the Morning Gene vaccines may be relatively new, but they're the logical outgrowth of two familiar strands of medical science. |
Technology Research News June 16, 2004 |
Genes Automate DNA Machines Researchers have taken a step toward automating nanomachines with a method that allows instructions for a DNA-based machine to be contained in a gene, or another stretch of DNA. |
Chemistry World March 29, 2009 Lewis Brindley |
Gene gels pump out proteins Gels made with genes incorporated into the structure could soon make protein production cheaper and easier, according to researchers in the US. |
BusinessWeek April 22, 2010 Rob Waters |
Gene Therapy Takes a Turn for the Better Researchers and investors are heartened by advances in gene therapy. Analysts say revenues are still several years off, however. |
Chemistry World November 5, 2012 Andrew Turley |
Approval for first gene therapy drug Alipogene tiparvovec, marketed as Glybera, has become the first gene therapy drug to win approval in either the US or the EU. |
Chemistry World June 9, 2008 Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World May 21, 2012 Simon Hadlington |
Rewritable DNA for digital data storage A rewritable memory storage module can form the basis of a digital memory system, scientists suggest, with the cell being able to 'record' transient changes in its internal chemistry. |
IEEE Spectrum August 2006 Schoenbach et al. |
Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away. |
HHMI Bulletin Aug 2011 Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
Chemistry World July 29, 2015 Phillip Broadwith |
Biogen to develop gene therapies with AGTC The deal covers AGTC's development programs for several rare eye diseases using a viral-based gene delivery vector. |
Scientific American September 2009 Melinda Wenner |
Gene therapy: An Interview with an Unfortunate Pioneer Lessons learned by James M. Wilson, the scientist behind the first gene therapy death |
Chemistry World January 30, 2014 Anthony King |
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. |
Pharmaceutical Executive October 1, 2008 |
The other half of an HIV mystery is solved When HIV infects a human immune cell, which of the cell's own genes play a role? |
Salon.com June 1, 2000 Tabitha M. Powledge |
Gene therapy R.I.P.? When the country's biggest gene therapy institute was ordered to stop testing on humans last week, the action marked the end of an era fraught with dubious claims to success and a mess of unreported adverse effects. |
HHMI Bulletin February 2012 Sarah C.P. Williams |
The Twists and Turns of Immunity Fred Alt has built a career making sense of the immune system -- specifically, the diverse antibodies that fight off invading molecules, from viruses to cancer cells to pollen. |
Chemistry World November 27, 2007 James Mitchell Crow |
A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells. |
Reason Aug/Sep 2000 Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
Salon.com May 1, 2000 Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Popular Mechanics September 2006 Ben Harder |
Seeking Immunity Pathogens like West Nile virus show no respect for borders. But a new class of vaccines may soon keep them in check. |
Reason April 2007 Ronald Bailey |
Testing Your Strength The World Anti-Doping Agency is developing tests for a form of cheating that doesn't exist yet. The agency banned gene doping, the alteration of genes to enhance athletic performance. |
Chemistry World June 7, 2007 Jessica Ebert |
Sensitive Sequencing Technique for Early Diagnosis A new technique, with sensitivity unmatched by current technologies, can detect changes in gene transcription that occur during the course of a disease, report US researchers. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. |
Chemistry World October 1, 2014 Michael Gross |
Viruses melt 'glassy' DNA US Researchers have identified the factors that enable viral DNA to turn from solid to liquid, which allows them to infect host cells. They say the process could become a target for new antiviral therapies. |
Science News March 25, 2006 Janet Raloff |
Meat Poses Exaggerated Cancer Risk for Some People The National Toxicology Program confirmed that heterocyclic amines that form in overcooked meat can trigger colon cancer in animals and probably do the same in people. |
BusinessWeek February 10, 2011 Rob Waters |
Sangamo's Bet Against AIDS: Gene Therapy Sangamo's stock has more than doubled since July 6, when the company, with no products on the market, reported success of its gene therapy approach in mice in the journal Nature Biotechnology. |
Chemistry World January 31, 2008 John Bonner |
RNAi Scores Victory Against Crohn's Disease in Mice Thousands of people suffering from the debilitating gut condition Crohn's disease could experience relief from their symptoms through a technique that blocks production of a key protein in the inflammation process. |
Salon.com December 19, 2000 Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
Wired August 21, 2007 Bob Parks |
Scramble Some DNA With the Bio-Rad Helios Gene Gun Labs worldwide use a helium-powered gun for everything from shooting nano sensors into mice and flu-fighting genes into chickens to injecting potato DNA into rice, which makes the crop more insect- resistant. |
Popular Mechanics September 25, 2009 Erin McCarthy |
Fringe's Human Mutant Not Possible, Says Expert We won't ever have to worry about Fringe's part-mole-rat, part-scorpion, part-human mutant in real life because it's not within the realm of possibility. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Popular Mechanics April 15, 2009 Erin McCarthy |
Is Fringe's Genetic Monster Possible? Unlike the monster on Fringe, altered animals typically have only a single gene difference from non-altered animals -- but they can look different. |
The Motley Fool November 17, 2006 Jack Uldrich |
Neanderthal DNA Enlightens Investors Investors, the superb performance of 454's gene sequencing equipment on such a difficult and important project bodes well for its future prospects. |
Chemistry World November 8, 2012 Michael Parkin |
Nasal gel alternative to insulin injection Scientists has developed a novel insulin delivery system for nasal administration. The study aims to provide an alternative to regular injections through the delivery of insulin via the nasal membrane in the form of a hydrogel. |
Bio-IT World October 10, 2003 Donna Mendrick |
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Managed Care August 2004 Thomas Morrow |
10,000 Cells on a Chip Signal Start of New Era of Diagnosis Diseases will soon be defined by biochemical pathways and genetic interactions. Biochips may identify patients likely to respond to therapeutic agents. All of this is a big deal for health plans. |
IEEE Spectrum March 2011 Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
BusinessWeek May 9, 2005 John Carey |
Dr. Francis S. Collins: On The Trail Of Disease Genes Collins is leading the search for DNA variations that can result in illnesses. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
HHMI Bulletin Nov 2010 |
Fusion genes that drive solid tumors are a new target for cancer therapies The success of Gleevec and related drugs has inspired researchers to step up their hunt for the molecular defects underlying other cancers. |
AskMen.com |
Mean People A new study in the journal Psychological Science suggests that if people have certain gene variants, they're more likely to be nice. |
Chemistry World July 4, 2008 Emma Davies |
Creating a Second Genetic Code Japanese researchers have made artificial DNA that acts like the real thing, even forming right-handed duplexes with complementary artificial strands. |