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Chemistry World June 7, 2007 Jessica Ebert	Sensitive Sequencing Technique for Early Diagnosis A new technique, with sensitivity unmatched by current technologies, can detect changes in gene transcription that occur during the course of a disease, report US researchers.
Bio-IT World December 10, 2002 Rotem Sorek	Alternative Splicing: Listen to the Mouse The completed mouse genome may help to finally pin down the size of the transcriptome.
Bio-IT World September 2005 Kevin Davies	Fantastic 454: DNA Sequencing Pyrotechnics In an exciting advance for DNA sequencing technology, a research team at 454 Life Sciences Corp. has essentially sequenced and assembled a bacterial genome sequence based on a mere 4-hour run on the company's proprietary instrument.
HHMI Bulletin May 2012 Sarah C. P. Williams	Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases.
Bio-IT World October 10, 2003 Mel Kronick	In Situ Chips on Demand Microarray manufacturing technologies are giving new meaning to the term 'custom.'
HHMI Bulletin Winter 2013 Sarah C.P. Williams	Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning.
Chemistry World September 23, 2009 Simon Hadlington	Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly.
Chemistry World April 3, 2008 Lewis Brindley	DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists.
Salon.com May 1, 2000 Arthur Allen	Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic.
Chemistry World July 13, 2011 Hayley Birch	Naked mole-rat genome holds clue to beating cancer The recently published draft sequence of the naked mole-rat genome promises to reveal the secrets of its long and remarkably cancer-free existence, potentially providing new targets for anti-cancer drugs.
Bio-IT World July 11, 2002 Malorye Branca	Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed.
Bio-IT World April 15, 2003 Malorye Branca	Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease?
Bio-IT World Jul/Aug 2006 Deb Janssen	Managing the Microarray Data Mountain Genomic studies often involve thousands of samples and require hundreds of thousands of assays per sample. Microarray manufacturers are scurrying to satisfy researcher demands for increased array density, sample number, and content flexibility.
Bio-IT World August 15, 2005 Robert M. Frederickson	What's 'Post' About Postgenomic? Bioinformatics tools can help organize and study genomic sequences that were discovered in the '90s. The tools help with tasks like analyzing gene expression, predicting protein structure and function, and establishing networks of interacting protein in cells.
Bio-IT World December 15, 2004 William Marshall	Applications of RNAi RNA interference is a highly coordinated gene regulatory mechanism that appears to be highly conserved across all metazoans studied thus far.
Bio-IT World February 10, 2003 Kevin Davies	With a Click of the Mouse What do Eminem and Mus musculus have in common? About 30,000 genes, for a start. The author mulls over the second mammalian genome.
Bio-IT World January 13, 2003 Malorye Branca	The Power of Expression Clayton Naeve's annual budget tripled overnight. Naeve is director of what was formerly called The Biotechnology Center, at St. Jude Children's Research Hospital. The windfall came from an anonymous donor who pledged $5 million a year to the Center for the next five years.
Bio-IT World Dec 2006/Jan 2007 Kevin Davies	The One Percent Difference New research reveals a shocking new layer of human genome variation with profound implications for the future of genomic analysis and personalized medicine.
BusinessWeek October 23, 2008 John Carey	Reading the Entire Genetic Code Pioneers such as 23andMe and Navigenics use snips of genes to make medical predictions. Now new tools from more start-ups are on the horizon.
Bio-IT World November 14, 2003 Julia Boguslavsky	Genome Center in a Box Scientists at 454 Life Sciences developed an integrated end-to-end instrument that performs hundreds of thousands of reactions in parallel -- from sample preparation, amplification, and sequencing to data storage and bioinformatics.
Bio-IT World September 11, 2003 Kevin Davies	Chipping Away at Cancer In Vivo, In Situ Two studies probe new applications of DNA microarrays, revealing new insights into the pathogenesis and pharmacogenomics of cancer.
Bio-IT World November 2005	News Blast Applied Biosystems contributes 400,000 primers... Researchers have discovered the full genetic sequence of many different strains of the flu... Sigma-Aldrich launches Panorama Human Cancer Version 1 Protein Functional Microarray...
IEEE Spectrum March 2013 Eliza Strickland	The Gene Machine and Me Ion Torrent's chip-based genome sequencer is cheap, fast, and poised to revolutionize medicine
Wired August 2000 Jennifer Hillner	Area 22 The inside story of the first fully sequenced chromosome.
Bio-IT World November 2006 Kevin Davies	Compute for the Cure Computational comparison offers a seductive new approach to identify new drugs for disease, as well as re-purposing existing drugs.
Technology Research News April 9, 2003 Kimberly Patch	Glowing beads make tiny bar codes Researchers from Corning, Inc. have found a way to form tiny barcoded beads that are small enough to be embedded in ink and attached to DNA molecules.
Fast Company November 2009 David H. Freedman	The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens.
Bio-IT World April 2006 Karen Hopkin	AGBT Meeting Puts Genome Advances Front and Center If the presentations at February's Advances in Genome Biology and Technology (AGBT) are any indication, the race to generate fresh approaches to produce more sequence for less is far from over -- and looks to be heating up.
Reason Aug/Sep 2000 Ronald Bailey	Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley
Bio-IT World July 2005 Robert M. Frederickson	Amassing Mass Spectrometry Tools Mass spectrometry is a key tool in the effort to identify protein biomarkers of human disease. Manufacturers have met major challenges in adapting this technology to protein discovery, both qualitatively and quantitatively.
Reactive Reports Apr/May 2005 David Bradley	At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule.
Chemistry World October 17, 2011 Hayley Birch	Quickly sorting cells using DNA A new magnetic cell sorting technique uses principles borrowed from DNA nanodevices. The approach could help scientists rapidly separate different types of cells from complex mixtures.
Bio-IT World December 10, 2002 Kevin Davies	The Wit and Wisdom of Uncle Syd This year, the Nobel Prize committee got it right by finally awarding a share of the physiology or medicine prize to Sydney Brenner, at the tender age of 75.
IEEE Spectrum March 2011 Lucks & Arkin	Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering
Bio-IT World September 2005 Kristen Amuzzini	A More Efficient Approach to Biostatistical Data Analysis Using an efficient, integrated approach, data from many different sources can easily be acquired, massaged to ensure its integrity, and then combined into single tables that biostatisticians can use to search for patterns regardless of the source of the data.
Chemistry World January 28, 2011 David Barden	Chips make short work of RNA synthesis Chinese scientists have developed a much easier way to make the short strands of RNA that are an essential tool in understanding what genes do.
Bio-IT World December 15, 2003 Zachary Zimmerman	Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology.
Bio-IT World October 10, 2003 Donna Mendrick	Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials.
Bio-IT World January 13, 2003 Julia Boguslavsky	A Sequel to the Sequence The all-but-complete human genome sequence is not only an indispensable tool for biomedical research but also a major influence on the types of instrumentation researchers will invest in.
Salon.com February 13, 2001 Arthur Allen	Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly...
Bio-IT World May 2006 Kevin Davies	Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles.
Bio-IT World November 19, 2004 Kevin Davies	The Book on Bioinformatics Research director David Mount talks about his new book "Bioinformatics: Sequence and Genome Analysis," sequence analysis, and teaching bioinformatics
Reactive Reports Issue 58	ID Tags for Teenage Molecules One academic team has developed a logical technology that allows them to generate millions of unique tags to track sub-microscopic objects.
Bio-IT World November 14, 2003 Jeff Augen	Making Information-Based Medicine Work A confluence of scientific discovery and high-throughput technology has made information-based medicine possible -- and imperative.
Bio-IT World November 12, 2002 Paula Campbell Evans	Patently More Difficult The PTO has targeted gene patents with new application guidelines. Here's what they mean and how biotech companies can satisfy them.
Managed Care August 2007 Thomas Morrow	Gene Expression Microarray Improves Prediction of Breast Cancer Outcomes Flash-frozen samples of surgically removed breast cancer tissue are the key to measuring a patient's risk of metastasis.
Bio-IT World July 2005 Kevin Davies	Medicine Gets Personal Touch More genomics-based drugs are moving into development with others, such as new cancer drugs showcasing on the clinical pharmacogenics scene as outlined in the Advances in Genomic Medicine program of a recent world conference.
Chemistry World June 26, 2008 Bea Perks	Liquid Crystals Stand up for DNA Detection Liquid crystals that realign in response to DNA can reveal subtle sequence alterations, even a single base mutation, report US scientists.
Chemistry World November 27, 2007 James Mitchell Crow	A Flare for Gene Silencing US scientists have developed nanoparticle probes coated with DNA that release fluorescent 'flares' when they silence genes inside cells.
Bio-IT World April 15, 2003 Mark D. Uehling	Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials.