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Chemistry World April 5, 2007 Victoria Gill |
Target for Memory-Enhancing Pills Identified Researchers have taken a step towards developing a pill that could improve memory by pinpointing and testing a potential target enzyme in the brain. |
Popular Mechanics February 13, 2009 Erin McCarthy |
Dollhouse's Memory Science Mixes Fact with Fiction Memory erasure might seem like pure sci-fi, but it's actually on the cutting edge of science. Three memory experts separate what's fact from what's fiction on Fox's new show, Dollhouse, premiering tonight at 9 pm. |
HHMI Bulletin February 2012 Nicole Kresge |
Protein Precision in the Brain with CSF Two causes of autism arise from opposite cellular mechanisms. Too much or too little protein production at the synapse between neurons can cause autism and intellectual disability. |
HHMI Bulletin Aug 2011 Kelly Chi |
Lasting Memories Measuring molecules at a single synapse gives clues to how memories become long term. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Forgetting Fear A compound given at just the right time may make mice forget to be afraid. |
Chemistry World October 31, 2007 John Bonner |
Brain's Wiring Seen in Technicolor Researchers in the US have developed a technique that could allow neurologists to draw a detailed wiring plan of the mammalian brain by inserting genes coding for fluorescent proteins into transgenic mice. |
AskMen.com Jacob Franek |
Alzheimer's Disease 101 It's only in the last decade or so that we have truly come to understand the various disorders of the brain that are associated with age and, in most cases, Alzheimer's disease is the prime suspect. Read on for some basic information. |
HHMI Bulletin May 2010 Lauren Gravitz |
Live Long and Prosper Mix amyloid plaques with longevity and you get mice that not only live longer, but healthier too. |
Chemistry World July 20, 2012 Michael Parkin |
New supramolecular Alzheimer's drugs Supramolecular chemistry could provide a new avenue in the treatment of Alzheimer's disease, say scientists in China. |
Chemistry World October 4, 2007 John Bonner |
How Traumatic Events Leave a Mark on the Brain Researchers in the US have a discovered a potential mechanism to explain why people retain stronger memories of events that occur in emotionally charged situations. |
Chemistry World December 19, 2007 Simon Hadlington |
Snapshot of Proteins Linked to Autism Researchers in France and the US have caught on camera the gentle embrace between two proteins that sit on either side of the junction between nerve cells. It's this short circuit that has thought to cause some types of autism. |
HHMI Bulletin Nov 2010 Mitch Leslie |
Immune System Defects Can Cause Obsessive Behavior A shortage of certain immune cells might prompt obsessive-compulsive disorder. |
HHMI Bulletin May 2011 Madeline Drexler |
Mark Bear: Charting New Waters Bear has applied his discoveries in brain plasticity to understanding fragile X syndrome, an inherited form of mental impairment. |
HHMI Bulletin May 2010 Jeffrey M. Perkel |
A Brighter View of the Brain in Action A protein sensor is beefed up to illuminate the language of neural networks. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
Chemistry World January 30, 2012 James Urquhart |
Iron accumulation linked to neurogenerative disease Parkinson's and Alzheimer's could be caused by an accumulation of iron in regions of the brain, Australian researchers say. |
HHMI Bulletin May 2011 Corinna Wu |
Mouse Cam Tracking techniques offer a long-term view into the mouse brain. |
Chemistry World July 3, 2014 Maria Burke |
Renewed focus on dementia checked by drug challenges The risks and barriers for companies working in dementia are huge, but so too, potentially, are the rewards, says Simon Ridley, head of research at Alzheimer's Research UK. |
Chemistry World February 24, 2011 Carl Saxton |
Mapping brain networks US scientists have created a model of the ring-shaped networks of neurons in the brain, which could help researchers to understand small changes within diseased brain cells. |
HHMI Bulletin Feb 2012 Nicole Kresge |
Now You See It, Now You Don't A disappearing receptor could hold the key to beta-cell growth and insulin production. |
Chemistry World September 21, 2006 Michael Gross |
Alzheimer's Alphabet Alzheimer's researchers are now closer to understanding the natural function of one of the two enzymes that cut A out of APP, and have recreated the process by which fibril formation begins in vivo. |
Pharmaceutical Executive August 1, 2008 Patrick Clinton |
Salute to the Murines What can we say about modern medicine? The answer, of course, is that it's brilliant at curing the ailments of mice. |
HHMI Bulletin May 2010 Sarah Goforth |
Scratching the Surface There's nothing funny about an itch that drives you mad. |
Chemistry World June 19, 2012 Anthony King |
Nanoparticles linked to rheumatoid arthritis Three types of nanoparticles were found to ramp up protein citrullination in cell cultures, a change that can make the body think native proteins are foreign. This process has previously been linked to autoimmune disease. |
Chemistry World September 17, 2009 Simon Hadlington |
Targeted TB treatment Researchers in the US have discovered that a class of small molecules can selectively disable a key protein complex in the tuberculosis bacterium and kill the organism |
Chemistry World August 26, 2008 Fred Campbell |
High-throughput protein microarrays on the way A new method to rapidly generate protein microarrays has been developed by UK researchers at the University of Manchester. |
Chemistry World June 1, 2012 Simon Hadlington |
Protein architecture with atomic precision Researchers have made a key breakthrough in designing and building geometrically defined nanostructures from proteins with unprecedented accuracy. |
HHMI Bulletin May 2012 Nicole Kresge |
Reduce and Recycle According to investigator Beth Levine, cells break down cellular junk to get extra energy, thereby cleaning house while you exercise. |
Chemistry World January 3, 2007 Victoria Gill |
Alzheimer's Protein Fingerprint Alzheimer's disease, a debilitating neurodegenerative disorder that eventually results in wasting of the whole brain, offers a chemical clue that should make it easier to spot and possibly easier to treat. |
Scientific American November 2005 Charles Q. Choi |
Baby to Brain Mothers could literally always have their kids on their minds. Researchers find that in mice, cells from fetuses can migrate into a mother's brain and apparently develop into nervous system cells. |
Science News October 14, 2006 Ivars Peterson |
Knots in Proteins Knotted proteins are rare, but more than just random occurrences. The secret of spontaneous knotting lies in the mathematics of self-avoiding random walks. |
Chemistry World November 30, 2006 Jessica Ebert |
Morning After Pill Might Prevent Breast Cancer The active ingredient of the morning-after pill -- mifepristone, or RU-486 -- prevents the formation of mammary-cell tumours in mice with a mutation in the breast cancer susceptibility gene, BRCA1, report scientists. |
Chemistry World December 19, 2012 Amy Middleton-Gear |
Early Alzheimer's diagnosis compound UK and US scientists have developed a labelled tracer compound that binds to plaques closely associated with Alzheimer's disease so that the plaques can be picked up by a medical imaging technique. |
Chemistry World November 13, 2014 Katrina Kramer |
Persuading proteins to form porous polyhedra Researchers in the US have designed a hollow cube out of naturally occurring proteins, something that was previously only possible with DNA. |
Chemistry World May 12, 2008 Simon Hadlington |
'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria. |
Chemistry World December 21, 2006 Tom Westgate |
Molecular Probe Identifies Patients at Risk of Alzheimer's A new molecule could provide an early warning system for Alzheimer's disease, US researchers hope. |
BusinessWeek July 26, 2004 Arlene Weintraub |
The Stem-Cell Flap: Simmer Down Advocates are overstating stem cells' near-term ability to treat grave illnesses. In doing so, they not only distort the science; the hopes they raise among many people who are sick today are also sure to be dashed. |
HHMI Bulletin Aug 2011 Janelle Weaver |
Leading a Double Life with CSF Lucky for us, the organs in our bodies come with a self-repair kit. Though regularly bombarded by harmful bacteria, more often than not they manage to heal themselves. How this happens has puzzled scientists, but now there may be some answers. |
Nurse Practitioner August 2011 Davis et al. |
Supportive approaches for Alzheimer Disease Alzheimer disease accounts for almost 80% of all dementia diagnoses. Currently, more than 5 million Americans suffer from this debilitating illness, with the highest prevalence in the oldest age groups. |
AskMen.com Dave Golokhov |
Caloric Restriction And Memory A new Italian study on caloric restriction has shown that eating less can give your memory a boost and improve your learning. |
HHMI Bulletin Aug 2011 Cassandra Willyard |
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
Chemistry World November 2, 2006 Michael Gross |
Alzheimer's Century Researchers worldwide are commemorating the centenary of Alois Alzheimer's first description of the dementia named after him. |
Chemistry World December 21, 2006 Henry Nicholls |
Silent SNPs Serve up a Structural Surprise The sequence of amino acids no longer dictates the structure and function of a protein according to a surprising new paper. |
Chemistry World October 2, 2012 Fiona McKenzie |
Protein sorting within cells US scientists have used magnetic nanoparticles with specific ligands to latch on to and visualize specific proteins in living cells. |
Reactive Reports October 2006 David Bradley |
Drink Up! Lest We Forget There is potentially good news for red wine lovers whose favorite tipple is Cabernet Sauvignon. Researchers have found that moderate consumption of Cabernet Sauvignon can attenuate neural degradation in laboratory mice with Alzheimer's disease. |
BusinessWeek July 15, 2010 Lopatto & Matsuyama |
The Race for Diagnostic Tests for Alzheimer's GE, Bayer, and Avid are vying to be first to market an early test for Alzheimer's. |
Reactive Reports September 2005 David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
Chemistry World June 3, 2015 Matthew Gunther |
Chemistry Nobel laureate Irwin Rose dies aged 88 Rose, along with Aaron Ciechanover and Avram Hershko, received the prize for discovering how cells break down and dispose of unwanted proteins. |
Chemistry World November 6, 2015 Emma Stoye |
Eye drops show promise treating cataracts and even reversing damage A molecule that can bind and re-solubilize misfolded proteins in the eye has been identified by researchers in the US. |