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Chemistry World
December 9, 2013
James Urquhart |
Drug fix for misfolded proteins promises hope for incurable diseases Researchers have been looking into pharmacological chaperones or pharmacoperones. They might treat diseases brought about by genetic mutations that cause otherwise functional proteins to become misfolded or misrouted.   |
HHMI Bulletin
February 2011
Sarah C.P. Williams |
Forgetting Fear A compound given at just the right time may make mice forget to be afraid. |
Chemistry World
January 13, 2008
Ananyo Bhattacharya |
Unexpected Effects of Drug Combinations Medicines that use a combination of several drugs can sometimes produce unexpected effects in patients. Now, a team of scientists think they have figured out how that can happen. |
Chemistry World
October 7, 2012
David Bradley |
Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea. |
HHMI Bulletin
Spring 2013
Nicole Kresge |
Itching to Be Discovered When the receptor for capsaicin -- the chemical that gives heat to chili peppers -- is added to itch-sensing neurons, exposure to the normally painful capsaicin causes itchiness. |
Chemistry World
February 12, 2009
Simon Hadlington |
Mystery receptor's binding partner uncovered For decades scientists have puzzled over the role of the sigma-1 receptor, a protein found in almost all mammalian cells, including the nervous system. |
Chemistry World
February 23, 2009
Nina Notman |
Resistant breast cancers re-sensitised to Tamoxifen A way to re-sensitise certain drug-resistant breast cancers to treatments such as Tamoxifen could offer better treatment for people with hard-to-beat cancers. |
Reactive Reports
Apr/May 2005
David Bradley |
Of Mice and Women Mice lacking a molecule usually found on the surface of cells in the womb have fertility problems, according to a study by researchers. |
HHMI Bulletin
Feb 2012
Mary Bates |
Passing the Sniff Test Researchers are mapping the chemical signaling behind how mice detect friend and foe. |
Chemistry World
October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Chemistry World
July 21, 2011
Elinor Richards |
Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells. |
Chemistry World
October 18, 2012 |
A signal honor The 2012 Nobel prize in chemistry was awarded to Robert Lefkowitz and Brian Kobilka for studies of G-protein-coupled receptors. This article looks at the molecular machinery underpinning cell signaling. |
Chemistry World
March 6, 2011
Mike Brown |
Molecules that walk, hop and jump 'Two legged' molecules walk, hop and fly across a receptor surface, according to researchers in the Netherlands and Ireland. The findings could help us understand how viruses and bacteria interact with cell membranes, they say. |
Reactive Reports
Issue 58 |
Drug Discovery at a Snail's Pace Researchers isolated a toxin from the venomous cone sea snail. This nerve poison latches on to brain receptors and its chemical structure could be used to design new drugs that interact with these receptors and treat psychiatric and brain diseases. |
Scientific American
August 2008
Christine Soares |
Nicotine Replacement Drug's Bad Trip Pfizer's smoking-cessation aid tied to psychiatric episodes. |
The Motley Fool
March 14, 2008
Brian Orelli |
Weighing In on Obesity Drugs Could investing in drugmakers that produce weight-loss drugs help fatten your wallet? |
Chemistry World
July 2, 2013
Jeanne Therese Andres |
Mapping receptors in the brain Scientists from the UK and Germany have developed new compounds that target and bind to brain proteins linked to serious neurological disorders. |
Chemistry World
August 31, 2007
Lionel Milgrom |
Gut's Taste for the Sweet Life Revealed A sugar-sensing receptor in the intestine could explain why drinking diet cola may hinder obese people who hope to lose weight and lead to new ways of treating obesity and diabetes. |
Salon.com
August 9, 2000
Cynthia Kuhn & Wilkie Wilson |
Medicinal muse Can one become more creative by doing drugs? |
HHMI Bulletin
Feb 2012
Nicole Kresge |
Now You See It, Now You Don't A disappearing receptor could hold the key to beta-cell growth and insulin production. |
