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Bio-IT World
April 2007
Kevin Davies
The Human Metabolome Project Motivated by the absence of a metabolomic equivalent of GenBank that could provide information and possibly even samples of metabolites, researchers secured $7.5 million funding from Genome Canada in 2005 for the "Human Metabolome Project." mark for My Articles similar articles
Scientific American
February 28, 2005
Gunjan Sinha
The Diet That Fits With the understanding that some diseases such as obesity are metabolic syndromes in which multiple biochemical pathways interact to cause complex symptoms, metabolic testing offers a way to gauge health over a lifetime. mark for My Articles similar articles
Chemistry World
April 21, 2008
Pete Mitchel
The hunt for metabolic biomarkers In the largest metabonomics study ever carried out, researchers have discovered strong correlations between individuals' blood pressure and the levels of certain metabolites in their urine. mark for My Articles similar articles
Scientific American
June 2008
Melinda Wenner
Jeremy Nicholson's Gut Instincts: Researching Intestinal Bacteria The body and its intestinal flora produce chemicals with hidden health information, Jeremy Nicholson has found. Someday treating disease may mean treating those bacteria. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Malorye Branca
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? mark for My Articles similar articles
Chemistry World
July 2010
Anna Lewcock
Medicine made to measure Healthcare tailored to suit the genetic makeup of the patient is finally coming to fruition. mark for My Articles similar articles
Bio-IT World
August 13, 2002
Malorye Branca
The Proteomics Odyssey Efforts to map the constellation of protein interactions in humans gather momentum as companies vie to provide tools to capitalize on the potential of proteomics. But can proteomics prevail where some feel genomics has failed? mark for My Articles similar articles
Industrial Physicist
Jennifer Ouellette
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems mark for My Articles similar articles
Scientific American
November 14, 2005
Gunjan Sinha
Bugs and Drugs Gut bacteria could determine how well medicines work. mark for My Articles similar articles
Bio-IT World
May 2006
John Russell
Metabolon's Bet on Biochemistry CEO of biopharma Metabolon is betting on metabolomics to provide a better approach to new drug discovery. mark for My Articles similar articles
Chemistry World
January 27, 2011
Elinor Richards
Diet affects cholesterol drug Copper and zinc in the diet could impair the action of statin drugs, compounds prescribed to lower cholesterol, say US scientists. mark for My Articles similar articles
Chemistry World
March 7, 2011
Russell Johnson
Breathe out for personalised medicine A method to analyse drug levels in the body could allow people with epilepsy to avoid weeks of blood tests, claim scientists from Switzerland. mark for My Articles similar articles
Bio-IT World
July 11, 2002
Malorye Branca
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. mark for My Articles similar articles
Chemistry World
November 15, 2012
Laura Howes
Imperial launches second phenome centre Imperial College London, UK, is launching a new clinical phenome center at St Mary's Hospital London, to analyze the phenotypes of patient's samples. The phenotype includes all external products of genes and environment, from hair colour to chemical markers of disease states. mark for My Articles similar articles
Chemistry World
July 2010
Hayley Birch
Special Report: Health breakthroughs of the decade New discoveries have been made with cancer vaccines, genomics, statin drugs, allosteric modulators, and RNA interference during the last decade. mark for My Articles similar articles
Chemistry World
August 1, 2012
Patrick Walter
Phenomenal Olympic science legacy (or is that sustainability?) What do you do with a lab set up solely to catch Olympic drug cheats once the games are over? In the case of the London 2012 games, the answer is to turn it into a state of the art analytical lab. mark for My Articles similar articles
Bio-IT World
February 2006
John Russell
Inside BG Medicine Think Intel Inside, but instead of microprocessors, think industrial-strength experimental platforms, focused on all things omic, designed and even run by a third party, but living deep inside biopharmaceutical companies. This is BM Medicine's CEO Pieter Muntendam's strategy. mark for My Articles similar articles
Fast Company
November 2009
David H. Freedman
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. mark for My Articles similar articles
Chemistry World
September 30, 2010
Andrew Turley
Bacteria factories for Taxol precursors Researchers have engineered bacteria to produce precursors of Taxol (paclitaxel), one of the most widely used cancer drugs. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
Bio-IT World
November 12, 2002
Michael Goldman
A Virtual Pharmacopeia Computational modeling of disease pathways, organs --- even patients --- could transform drug discovery. Does salvation exist in silico? mark for My Articles similar articles
Wired
April 21, 2008
Rachel Swaby
Chromosome, Proteome ... Decoding the DNA of '-omes' The genome alone can't explain how our bodies work. We need to decode a lot of other complex biological systems that regulate how we develop. mark for My Articles similar articles
Chemistry World
April 11, 2007
Victoria Gill
A Dog's Life A group of dogs that enjoyed long lives on carefully planned diets has provided researchers with a unique life-long metabolic profile. The data reveal the relationship between diet, disease and longevity. mark for My Articles similar articles
Bio-IT World
November 12, 2002
James Golden
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. mark for My Articles similar articles
Salon.com
May 1, 2000
Arthur Allen
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. mark for My Articles similar articles
Bio-IT World
September 2006
John A. Wass
Integrating Knowledge The results of new mathematical routines have the potential to save pharmaceuticals millions of dollars in drug development. And yet the flow of successful drugs is dwindling. The problem goes beyond bureaucracy and lies in the complexity of the problem. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Donna Mendrick
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. mark for My Articles similar articles
Chemistry World
September 24, 2013
Jennifer Newton
Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Bio-IT World
July 14, 2004
Malorye A. Branca
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. mark for My Articles similar articles
Bio-IT World
September 2005
Kristen Amuzzini
A More Efficient Approach to Biostatistical Data Analysis Using an efficient, integrated approach, data from many different sources can easily be acquired, massaged to ensure its integrity, and then combined into single tables that biostatisticians can use to search for patterns regardless of the source of the data. mark for My Articles similar articles
Chemistry World
November 2, 2015
Charlie Quigg
Biomarkers identify stroke victims with cognitive problems Scientists in China have pinpointed three metabolites that indicate if a stroke victim has suffered cognitive damage. mark for My Articles similar articles
Knowledge@Wharton From Skin Creams to Life Insurance to Medical Care, Biosciences Are the New Frontier of Business Opportunity Research in the biological sciences holds the potential for breakthroughs that could transform the world. But scientific advances also can be baffling and more than a little intimidating, especially for business people... mark for My Articles similar articles
Bio-IT World
Jul/Aug 2006
Eric K. Neumann
Combining Drug Toxicity Knowledge Nearly half the drugs entering clinical trials will fail because of some form of serious toxicity that was missed in preclinical studies. These failures should not happen at such a late stage in the process. So what can be done? mark for My Articles similar articles
Bio-IT World
January 13, 2003
John Dodge
Talent Fuels Drug Pipeline in Swiss Time The functional genomics group has emerged as a critical link in the drug discovery chain at Novartis Pharmaceuticals Corp. While it employs a multidisciplinary approach to drug discovery, the four-year-old group's goals could not be simpler: Find novel drug targets. mark for My Articles similar articles
Bio-IT World
May 2006
Robert M. Frederickson
A New (Bio)Spin on NMR Applications Bruker BioSpin recently announced several introductions to improve throughput, sensitivity, and versatility of its systems for nuclear magnetic resonance applications starting with the SampleJet, a robotics system for high-throughput transfers of NMR sample tubes into the NMR spectrometer. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Salvatore Salamone
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. mark for My Articles similar articles
Managed Care
August 2004
Thomas Morrow
10,000 Cells on a Chip Signal Start of New Era of Diagnosis Diseases will soon be defined by biochemical pathways and genetic interactions. Biochips may identify patients likely to respond to therapeutic agents. All of this is a big deal for health plans. mark for My Articles similar articles
Bio-IT World
December 15, 2003
Zachary Zimmerman
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. mark for My Articles similar articles
Bio-IT World
October 14, 2004
Zachary Zimmerman
Follow the Pathway to Increased ROI Although this software has been commercially available for only a year, Ingenuity claims nine of the top 10 pharmaceutical companies as customers, including Pfizer, Wyeth, GlaxoSmithKline, and Aventis. mark for My Articles similar articles
Wired
August 2000
Jennifer Hillner
Area 22 The inside story of the first fully sequenced chromosome. mark for My Articles similar articles
HHMI Bulletin
Aug 2010
Sarah C.P. Williams
Switching Plants' Reproductive Methods The shipments of seeds that farms rely on at the beginning of each growing season could soon be a relic of the past. Scientists have discovered how to coax plants to clone themselves by altering their reproductive methods. mark for My Articles similar articles
Bio-IT World
May 2006
Kevin Davies
Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles. mark for My Articles similar articles
Chemistry World
June 14, 2011
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. mark for My Articles similar articles
BusinessWeek
June 13, 2005
John Carey
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. mark for My Articles similar articles
Bio-IT World
July 2005
Robert M. Frederickson
Amassing Mass Spectrometry Tools Mass spectrometry is a key tool in the effort to identify protein biomarkers of human disease. Manufacturers have met major challenges in adapting this technology to protein discovery, both qualitatively and quantitatively. mark for My Articles similar articles
Chemistry World
May 17, 2006
Bea Perks
Biochemists Reveal Hidden Drug Effects Researchers have identified unexpected drug activities by probing biochemical pathways inside living cells. mark for My Articles similar articles
Fast Company
September 2000
John Ellis
The Secret of Life The mapping of the human genome, says Craig Venter, will change science, research, medicine, politics, health insurance, and the way biology looks at the last 3 billion years of evolution. And that's just the beginning. mark for My Articles similar articles
The Motley Fool
December 10, 2004
Rich Duprey
Scientists Play Chicken An international scientific consortium decodes the chicken genome. This information may be of use to companies such as Tyson, Pilgrim's Pride, Cal-Maine or even Buffalo Wild Wings. mark for My Articles similar articles
Chemistry World
May 1, 2014
James Urquhart
Ancient oceans' metals mimicked metabolism Primitive metabolism of sugar phosphates may have started spontaneously in ancient oceans around 4 billion years ago and given rise to life, according to UK researchers. mark for My Articles similar articles