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Chemistry World January 13, 2012 Helen Potter	Mineral regulates early metabolism Chinese scientists have taken a step towards further understanding the reactions that led to the origin of life by showing that a crucial metabolic process can be photocatalysed on the surface of a common mineral.
Chemistry World August 7, 2011 Phillip Broadwith	Possible Origin of Chirality in the Rna World Given a tiny push one way or the other, simple racemic precursors can lead to the chiral building blocks of RNA using a combination of chemical and physical factors.
Chemistry World January 17, 2014 Katia Moskvitch	Life may have begun in a tiny water droplet Chemical reactions run much faster and more efficiently when they take place in tiny droplets rather than in freestanding water -- such as a puddle or a lake, say researchers.
Chemistry World March 17, 2015 Andy Extance	Reaction map suggests meteorite chemistry route to life UK chemists have found a reaction network that they believe shows that 'pretty much everyone' working on life's molecular origins is wrong -- but also 'right, in a sense'.
Chemistry World February 13, 2012 Andy Extance	Protocells called thermal springs home The first 'protocells' may have arisen in puddles of liquid spewed onto the ancient Earth's surface by thermal springs rather than near deep sea hydrothermal vents.
Chemistry World February 6, 2011 Laura Howes	Cells as test tubes Chemists have used living cells as test tubes to carry out chemical reactions never before seen within living cells.
Chemistry World February 11, 2013 Philip Ball	A (chemical) potential theory of life's origin This theory says that life arose at hydrothermal vents, not merely because these provide heat and the ingredients for making complex organics but because they create sustained gradients of ion concentration.
Chemistry World February 11, 2015 James Urquhart	'Early RNA' reactions characterized Researchers have shown how precursor nucleotide molecules could have self-polymerized without enzymes and subsequently given rise to the catalytic activity of the simplest, most ancient forms of RNA.
Chemistry World August 10, 2015 Kira Welter	Peptide glue may have held first protocell components together Electrostatic interactions induced by short, positively charged, hydrophobic peptides are all it takes to attach RNA to vesicle membranes.
Chemistry World March 6, 2008 Simon Hadlington	Synthetic Enzymes Designed by Computer Scientists in the US have designed and built an artificial enzyme from scratch.
Chemistry World April 19, 2012 Andy Extance	Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules.
Chemistry World August 10, 2009 James Urquhart	Stretching for reversible enzyme activation A new kind of biologically inspired nanomaterial that can be chemically turned on and off by mechanical stretching has been devised by French researchers.
Chemistry World May 5, 2015 James Urquhart	Ancient RNA enzymes formed from freeze-thaw cycles UK researchers have shown repeated cycles of freezing and thawing could have allowed the first complex RNA enzymes, or ribozymes, to form on early Earth -- a key step for the evolution of life.
Chemistry World October 29, 2009 Lewis Brindley	Cascading reactions in artificial cells Dutch researchers have started performing multi-step reactions inside artificial cells made from enzymes and polymers.
Chemistry World January 6, 2010 Phillip Broadwith	Enzymes do the twist The way enzyme catalysts bind molecules to speed up their reactions is not as simple as once thought, say chemists from the UK and Spain.
Chemistry World November 3, 2014 Debbie Houghton	Engineered metalloenzyme catalyses Friedel -- Crafts reaction Reprogramming the genetic code of bacteria to incorporate an unnatural amino acid has allowed scientists in the Netherlands to create a new metalloenzyme capable of catalyzing an enantioselective reaction.
Chemistry World May 15, 2014 Jenifer Mizen	Freeze-dried cells make better biocatalysts A biocatalytic cascade using mashed-up cells has overcome extraction and solubility problems associated with using enzymes in chemical syntheses.
Chemistry World November 26, 2012 Laura Howes	Protein coat prepares catalyst for cascades By protecting a transition metal catalyst with a protein coat, scientists have managed to couple up biocatalysts and chemical catalysts to perform a cascade reaction.
Chemistry World October 26, 2006 Victoria Gill	Volcanoes Reveal the Secret of the Origin of Life Life began with a chemical reaction under the sea over four billion years ago. That is the claim of a German scientist whose team has recreated a crucial part of the reaction, synthesizing all the necessary ingredients for a living organism.
Chemistry World January 21, 2011 Russell Johnson	Jump starting prebiotic photochemistry Light activated reactions of organic molecules in fatty acid membranes offers a plausible method for energy transfer and storage in prebiotic systems, claim US scientists.
Chemistry World May 13, 2009 James Urquhart	Insight into RNA origins UK researchers have offered new insight into the origins of RNA and possibly life itself.
Chemistry World December 10, 2014 Emma Stoye	Cutting edge chemistry in 2014 Highlights from last year's ground breaking chemical sciences research.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World July 3, 2015 Ida Emilie Steinmark	Iron found in ancient rock is recycled from bacteria Isotopic analysis suggests that some of the iron within rock formations was processed by bacteria 2.5 billion years ago
Chemistry World March 15, 2007 Henry Nicholls	The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue.
Chemistry World June 4, 2008 Simon Hadlington	Man-made protocell hosts DNA synthesis US researchers have taken a step towards creating a synthetic cell in the laboratory that could resemble the first primitive stirrings of life on Earth.
Chemistry World October 15, 2012 Melissae Fellet	Synthesis by mass spectrometry Chemists have used mass spectrometry, commonly used to analyze molecules, to synthesize them on the microscale.
Chemistry World May 20, 2013 Emma Stoye	RNA world hypothesis strengthened by iron The RNA world hypothesis has gained another boost after research shows that RNA is more catalytically active under conditions similar to those on Earth billions of years ago.
Chemistry World October 31, 2013 Derek Lowe	Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis.
Chemistry World January 11, 2007 Victoria Gill	How to Survive at 400 Degrees C Certain deep-sea residents manage to survive their searingly hot, toxic habitat by making their own food. Chemists in the US have now identified the molecules that make this possible.
Chemistry World November 25, 2014 James Urquhart	Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions.
Chemistry World September 21, 2009 Hayley Birch	Enzymes inspire new catalyst design for hydrogen production A novel enzyme-based catalyst developed by UK and US researchers hints at new ways of designing catalysts for the water-gas shift reaction, an important industrial reaction in the production of high grade hydrogen.
Chemistry World February 11, 2011 David Barden	Waking up to new possibilities in imaging UK researchers have used a cage-like molecule to smuggle metal ions into cells, which could improve medical imaging.
Chemistry World June 16, 2011	Forming the First Sugars with Formose Reactions Hydrothermal synthesis could provide greener synthesis methods as well as information about the origin of life.
Chemistry World August 13, 2007 Simon Hadlington	Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties.
Chemistry World January 17, 2014 Phillip Broadwith	Plug and play redox enzymes With the constant drive to make chemical synthesis ever cleaner, more energy-efficient and generate less waste -- both in research and industrial processes -- more and more chemists are looking to harness enzyme catalysis.
Chemistry World September 24, 2013 Jennifer Newton	Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products.
Chemistry World April 9, 2009 Lewis Brindley	'Nickel famine' caused ancient oxygen rise A crucial increase in atmospheric oxygen that occurred around 2.4 billion years ago could have been triggered by a shortage of nickel in the oceans, according to Canadian researchers.
Chemistry World April 20, 2009 James Urquhart	New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought.
Chemistry World June 11, 2009 James Urquhart	Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes.
Science News October 7, 2006	Timeline: From the October 3, 1936, Issue Steel and Concrete Hold 8,000,000-Pound Load... Living Organisms Found in Waters of the Dead Sea... Through Special Technique Enzyme is Viewed at Work...
Chemistry World August 12, 2010 Andy Extance	Science controversy authors fight on Researchers asked to retract a Science paper describing a tool for analyzing metabolic networks have vowed to validate their much-criticised work.
Chemistry World April 4, 2013 Phillip Broadwith	A solution to fluoronium riddle The first evidence for hypervalent fluorine cations, or fluoronium ions, in solution has been found by US chemists.
Chemistry World January 17, 2010 Simon Hadlington	Sugars synthesised with help of promiscuous enzyme European researchers have discovered a new way to make synthetically elusive sugar molecules that could lead to novel vaccine candidates and other medically important compounds.
Chemistry World December 20, 2011 Laura Howes	Cutting edge chemistry in 2011 With the help of an expert panel of journal editors Chemistry World reviews the ground breaking research and important trends in this year's crop of chemical science papers.
Chemistry World September 9, 2011 James Mitchell Crow	High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process.
Chemistry World February 17, 2013 Simon Hadlington	Enzyme nano-parcels sober up drunken mice Scientists in the US and China have invented a way to encapsulate teams of enzymes in a thin polymer shell. This enables the enzymes to carry out a series of sequential reactions within an enclosed space -- as happens in nature.
Chemistry World May 12, 2008 Simon Hadlington	'Super-yeast' tackles unnatural proteins Researchers in the US have engineered yeast cells to produce large amounts of proteins containing unnatural amino acids (UAAs) - a feat that has previously only been possible with bacteria.
Chemistry World October 8, 2013 Hayley Birch	RNA mimic destined for synthetic genome US scientists have taken another step towards the goal of creating self-replicating molecules like those thought to have spawned life on Earth. The researchers made RNA-like polymers capable of copying short sections of genetic code that they suggest could act as genomes in synthetic cells.
Scientific American June 2008 Melinda Wenner	How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness.