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Bio-IT World December 15, 2003 Zachary Zimmerman |
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. |
Bio-IT World November 12, 2002 Michael Goldman |
A Virtual Pharmacopeia Computational modeling of disease pathways, organs --- even patients --- could transform drug discovery. Does salvation exist in silico? |
Industrial Physicist Jennifer Ouellette |
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems |
Bio-IT World June 2006 Kevin Davies |
The Data Deluge: Deal or No Deal? Far from decrying the data glut, researchers should embrace the complexity of genomic and other sources of data, particularly for its predictive properties in the field of personalized medicine. |
Bio-IT World March 17, 2004 |
Systems Biology: Top-Down or Bottom-Up? Systems biology involves the representation and analysis of an intact biological system. Like many of the technological developments over the past 20 years, such as genomics, proteomics, combinatorial chemistry, and bioinformatics, pharma and medical communities hold high hopes that systems biology will help move molecular research closer to the practice of medicine. |
Bio-IT World June 12, 2002 John Dodge |
All Systems Go at ISB The Seattle-based Institute for Systems Biology (ISB), takes a holistic view of genomic and proteomic research. The author spoke with its president, noted biologist Leroy Hood, recently to find out how far ISB has come in its two years of life. |
Bio-IT World January 21, 2005 |
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. |
Bio-IT World August 13, 2002 Kevin Davies |
Hughes Offers a Helping Hand Under the assured leadership of Nobel Laureate Tom Cech, the Howard Hughes Medical Institute (HHMI) is increasingly applying its considerable resources to foster imaginative, interdisciplinary biomedical research and education. |
IEEE Spectrum February 2006 Samuel K. Moore |
Ajay Royyuru: Genographer In our genes: How this computational biologist traces the history of human migration through DNA data. |
Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Bio-IT World February 18, 2004 |
Pathology Goes Molecular New technologies are enabling clinical diagnostic laboratories to pave the way toward more personalized cancer therapies |
Industrial Physicist Apr/May 2003 Jennifer Oullette |
Switching from physics to biology Physicists in transition help shape biological theory. |
Bio-IT World October 10, 2003 Robert M. Frederickson |
Capturing Clinical Information Ardais is building a repository of clinical samples and related patient data. |
Bio-IT World June 12, 2002 Beth Schachter |
Informatics Moves to the Head of the Class The race is on to increase the quantity and quality of bio-IT training programs as government and academia bet the need will be great. Will the job market back up that bet? |
Bio-IT World September 16, 2004 Kevin Davies |
Computing the Genome Boston University's Charles DeLisi explains his involvement with the human genome project and why he has recently turned his attention to systems biology and an AIDS vaccine. |
Bio-IT World November 19, 2004 Kevin Davies |
The Book on Bioinformatics Research director David Mount talks about his new book "Bioinformatics: Sequence and Genome Analysis," sequence analysis, and teaching bioinformatics |
Bio-IT World November 14, 2003 Kathy Ordonez |
Targeted Medicine via Molecular Diagnostics Using diagnostics to select and deselect target populations for drug therapy will enable life scientists to make more effective medicines. |
Bio-IT World July 11, 2002 Malorye Branca |
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. |
Bio-IT World January 21, 2005 Salvatore Salamone |
A Prescription for Information-Based Medicine TurboWorx president and CEO Jeff Augen not only combines computational and biology expertise, but also has a clear vision of how to advance life science discovery. |
Bio-IT World Dec 2005/Jan 2006 |
News Blast Record Simulation... Merck-Ariadne Deal... Nano Group Forms... Database Debuts... |
Bio-IT World December 10, 2002 Hillel Alpert |
Bio-IT Shines Bright in Israel Companies such as Quark and Pharmos are still flourishing as other industries decline in this country torn by conflict. |
Bio-IT World November 12, 2002 James Golden |
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. |
CIO May 29, 2014 Stephanie Overby |
CIOs Join Forces to Battle Cancer A coalition of healthcare IT chiefs are on a mission to put cancer out of business and share IT best practices, technology tips, and personal support. |
Bio-IT World August 15, 2005 Kevin Davies |
Hood Hails 'Century of Biology' Leroy Hood won the 2005 Bio-IT World President's Award for his work on the synthesis of DNA and protein, and on the genome project. |
Bio-IT World September 2006 John Russell |
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. |
Pharmaceutical Executive July 1, 2011 Dickmeyer & Rosenbeck |
From Rut to Racetrack Can the pharmaceutical industry deliver on its objective to make cancer a curable, chronic condition? |
Chemistry World February 2011 |
Idle cures Taking a coffee break could help find cures for cancer or Aids. Katrina Megget looks at the future of research that harnesses the computing power of the World Community Grid |
Bio-IT World September 2006 Nat Goodman |
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. |
Bio-IT World October 9, 2002 Malorye Branca |
The Path to Personalized Medicine The tactics have changed, sometimes dramatically, but hints of the promise of pharmacogenomics are finally starting to trickle in from studies of asthma, cancer, and drug response. |
Bio-IT World December 10, 2002 |
Craig Venter Unvarnished (part II) The former Celera CEO covers privacy, ESTs, and his new research institutes. |
Bio-IT World November 14, 2003 Jeff Augen |
Making Information-Based Medicine Work A confluence of scientific discovery and high-throughput technology has made information-based medicine possible -- and imperative. |
Knowledge@Wharton |
From Skin Creams to Life Insurance to Medical Care, Biosciences Are the New Frontier of Business Opportunity Research in the biological sciences holds the potential for breakthroughs that could transform the world. But scientific advances also can be baffling and more than a little intimidating, especially for business people... |
Bio-IT World April 2007 John Russell |
Toward a Cancer Interactome Researchers at the Center for Cancer Systems Biology are working toward identifying the high level wiring diagram for cancer. In this instance, that means an accurate map of all cancer-associated protein-protein interactions. |
Bio-IT World June 15, 2003 Kevin Davies |
The Overly Bold and the Beautiful For many (who really ought to know better), the temptation to fetishize DNA is all but irresistible. |
Bio-IT World June 2006 Kevin Davies |
David Shaw: No Hedging on Future of Computer Simulations The computational scientist who founded the world's largest alternative investment firm says he is two years away from building a new breed of computer that could be a major breakthrough in structural biology -- simulating the process of protein folding and protein-drug interactions. |
Bio-IT World October 2006 John Russell |
GNS Charts "Unknown" Biology Gene Network Sciences' CEO and colleagues now think they have the right tool to mine the treasure trove of unknown biology hidden in the wealth of accumulating omic data. |
Wired August 2003 Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Bio-IT World July 14, 2004 Malorye A. Branca |
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. |
Bio-IT World August 13, 2002 Russell & Dodge |
Necessary Liaisons: Making Standards Work Caroline Kovac, IBM Corp.'s general manager for life sciences, talks about the need for standards and her take on the troubled informatics world. |
Bio-IT World May 9, 2003 |
Stephen Wolfram's New Science This is too big a thing to propagate through the standard mechanism of science, says Wolfram. Wolfram is convinced he's discovered a big idea that will change the world. An interview |
Bio-IT World September 2006 John Russell |
Predicting the Future of Systems Biology Buoyed by promising results from a recent collaboration with Pfizer on drug-induced vascular injury, Keith Elliston, CEO of modeling and biosimulation specialist Genstruct, offers a candid view of industry's flirtation with systems biology and the future prospects for the field. |
Bio-IT World January 12, 2004 Julia Boguslavsky |
New Year Tools for the 'New' Biology Instrumentation outlook for systems biology. |
Chemistry World July 6, 2012 |
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. |
Bio-IT World June 2005 John Russell |
India Genomics Institute Chooses HP Supercomputer The Institute of Genomics and Integrative Biology (IGIB) has chosen a 4-teraFLOPS Hewlett-Packard supercomputer running the Linux operating system to advance its life science computational biology research. |
Chemistry World January 2012 |
Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues. |
Bio-IT World January 13, 2003 John Dodge |
Talent Fuels Drug Pipeline in Swiss Time The functional genomics group has emerged as a critical link in the drug discovery chain at Novartis Pharmaceuticals Corp. While it employs a multidisciplinary approach to drug discovery, the four-year-old group's goals could not be simpler: Find novel drug targets. |
Bio-IT World June 17, 2004 John Russell |
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. |
Bio-IT World June 2005 Nancy J. Kelley |
Building Centers of Excellence in Translational Medicine New approaches to drug development that will be more effective in translating research to patient delivery will require the design and construction of new facilities that foster new ways of working among larger, multidisciplinary, teams of scientists and medical professionals in biology, chemistry, physics, mathematics, engineering, computer science, and, of course, information technology. |
Bio-IT World August 2005 |
Project Summaries Summaries of candidates for Bio-IT World's "Best Practices 2005" projects. |
HHMI Bulletin May 2010 Robert Tjian |
Biomolecular Crowdsourcing A generation of web-savvy entrepreneurs has found a relatively cheap and effective approach to solving complex problems and soliciting ideas: toss out a challenge into a vibrant digital community and watch what happens. |