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Chemistry World
May 5, 2015
James Urquhart
Ancient RNA enzymes formed from freeze-thaw cycles UK researchers have shown repeated cycles of freezing and thawing could have allowed the first complex RNA enzymes, or ribozymes, to form on early Earth -- a key step for the evolution of life. mark for My Articles similar articles
Chemistry World
October 18, 2012
Andy Extance
RNA teams up to beat selfish rivals A team from Portland State University has shown that cooperative ribozymes -- RNA enzymes -- outdo 'selfish' autocatalytic competitors for the same building blocks. mark for My Articles similar articles
Chemistry World
April 20, 2009
James Urquhart
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. mark for My Articles similar articles
Chemistry World
April 7, 2011
Laura Howes
Long chains give new life to RNA world hypothesis The so-called RNA world hypothesis has gained fresh momentum with the synthesis of the longest lab grown RNA strands made using an enzyme that is itself made of RNA, an 'RNAzyme'. mark for My Articles similar articles
Chemistry World
April 19, 2012
Andy Extance
Polymers perform non-DNA evolution Scientists have found that six polymer alternatives to DNA can pass on genetic information, and have evolved one type to specifically bind target molecules. mark for My Articles similar articles
Chemistry World
March 15, 2007
Henry Nicholls
The Mother of All Enzymes Scientists have uncovered the three-dimensional structure of what might be biology's first enzyme. This sheds light on the chemistry at a key moment in the origin of life, they argue. mark for My Articles similar articles
Chemistry World
May 20, 2013
Emma Stoye
RNA world hypothesis strengthened by iron The RNA world hypothesis has gained another boost after research shows that RNA is more catalytically active under conditions similar to those on Earth billions of years ago. mark for My Articles similar articles
Chemistry World
September 23, 2009
Simon Hadlington
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. mark for My Articles similar articles
Chemistry World
January 9, 2009
James Urquhart
Chemists edge closer to recreating early life A test tube based system of chemicals that exhibit life-like qualities such as indefinite self-replication, mutation, and survival of the fittest, has been created by US scientists. mark for My Articles similar articles
Chemistry World
May 13, 2009
James Urquhart
Insight into RNA origins UK researchers have offered new insight into the origins of RNA and possibly life itself. mark for My Articles similar articles
Chemistry World
May 1, 2014
James Urquhart
Ancient oceans' metals mimicked metabolism Primitive metabolism of sugar phosphates may have started spontaneously in ancient oceans around 4 billion years ago and given rise to life, according to UK researchers. mark for My Articles similar articles
Chemistry World
August 7, 2011
Phillip Broadwith
Possible Origin of Chirality in the Rna World Given a tiny push one way or the other, simple racemic precursors can lead to the chiral building blocks of RNA using a combination of chemical and physical factors. mark for My Articles similar articles
Chemistry World
January 8, 2012
David Bradley
The TNA world that came before the RNA one Once it was recognised that DNA is key to the molecular self-replication that underpins life, chemists have sought to understand the origins of this double-helical molecule in that primordial age. mark for My Articles similar articles
Chemistry World
February 27, 2006
Michael Gross
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. mark for My Articles similar articles
Technology Research News
January 12, 2005
RNA Tiles Form Nanopatterns Researchers have developed a method of coaxing artificial RNA molecules to self-assemble into specific shapes, much like a jigsaw puzzle automatically assembling. The structures could eventually be used as templates for nanochips, nanocircuits and nanocrystals mark for My Articles similar articles
Scientific American
March 2009
W. Wayt Gibbs
Evolution in a Bottle: Synthetic Life Oozes Closer to Reality Self-replicating RNAs advance science another step toward artificial life mark for My Articles similar articles
Scientific American
October 2008
Heather Wax
Using Math to Explain How Life on Earth Began How did self-replicating molecules come to dominate the early earth? Using the mathematics of evolutionary dynamics, Martin A. Nowak can explain the change from no life to life mark for My Articles similar articles
Chemistry World
March 8, 2010
Lewis Brindley
Molecular midwives helped birth of DNA 'Molecular midwives' - are compounds that played a crucial role in combining small nucleotide fragments into the first genetic polymeric material. mark for My Articles similar articles
Chemistry World
August 10, 2015
Kira Welter
Peptide glue may have held first protocell components together Electrostatic interactions induced by short, positively charged, hydrophobic peptides are all it takes to attach RNA to vesicle membranes. mark for My Articles similar articles
Technology Research News
June 29, 2005
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined. mark for My Articles similar articles
Chemistry World
September 7, 2009
Bolt-on MOF catalysts Chemists in the US have shown that a class of hugely porous materials called metal-organic frameworks (MOFs) can have catalytic functions bolted onto the structure after it has been constructed to produce efficient catalysts that can be easily recovered and cycled many times. mark for My Articles similar articles
Chemistry World
July 23, 2012
Melissae Fellet
RNA wrapper protects small molecules Step aside benzene rings, there's a new protecting group in town. Dutch researchers have used a strand of RNA to cover portions of a complex small molecule. They then chemically modified a portion of the molecule not covered by the RNA. mark for My Articles similar articles
Chemistry World
October 8, 2013
Hayley Birch
RNA mimic destined for synthetic genome US scientists have taken another step towards the goal of creating self-replicating molecules like those thought to have spawned life on Earth. The researchers made RNA-like polymers capable of copying short sections of genetic code that they suggest could act as genomes in synthetic cells. mark for My Articles similar articles
Scientific American
June 2005
JR Minkel
RNA to the Rescue The spectacular discovery that a species of plant can summon up genes its parents have lost highlights biologists' increasing recognition of RNA as a more versatile and important molecule in its own right. mark for My Articles similar articles
Chemistry World
January 28, 2011
David Barden
Chips make short work of RNA synthesis Chinese scientists have developed a much easier way to make the short strands of RNA that are an essential tool in understanding what genes do. mark for My Articles similar articles
Chemistry World
December 20, 2011
Laura Howes
Cutting edge chemistry in 2011 With the help of an expert panel of journal editors Chemistry World reviews the ground breaking research and important trends in this year's crop of chemical science papers. mark for My Articles similar articles
Scientific American
November 2007
Ed Regis
The Forgotten Code Cracker In the 1960s Marshall W. Nirenberg deciphered the genetic code, the combination of the A, T, G and C nucleotides that specify amino acids. So why do people think that Francis Crick did it? mark for My Articles similar articles
Chemistry World
June 11, 2009
James Urquhart
Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes. mark for My Articles similar articles
Chemistry World
November 2007
Philip Ball
Column: The Crucible It is inevitable that the origins of life on Earth will be forever shrouded in mystery. mark for My Articles similar articles
Chemistry World
March 14, 2012
James Urquhart
Catalysis at the flick of a switch German researchers have created a molecular nanoswitch that can be reversibly and repeatedly turned on and off to control a chemical reaction. mark for My Articles similar articles
Chemistry World
October 2, 2006
Bea Perks
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. mark for My Articles similar articles
Chemistry World
February 1, 2008
Lewis Brindley
Genetic Code Read Directly From RNA Scientists have directly read the genetic code from a single strand of RNA for the first time, using a combination of powerful microscopes and laser spectroscopy techniques. mark for My Articles similar articles
Chemistry World
August 2, 2011
Phillip Broadwith
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids. mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
Chemistry World
October 1, 2010
Hayley Birch
On-off catalyst mimics enzyme function US and Japanese researchers have created an enzyme-like catalyst whose activity can be switched on or off using small molecules. mark for My Articles similar articles
HHMI Bulletin
February 2012
Sarah C. P. Williams
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. mark for My Articles similar articles
Chemistry World
June 4, 2008
Simon Hadlington
Man-made protocell hosts DNA synthesis US researchers have taken a step towards creating a synthetic cell in the laboratory that could resemble the first primitive stirrings of life on Earth. mark for My Articles similar articles
Chemistry World
January 20, 2011
Hayley Birch
Programmable RNA promising for bio-compatible therapies Programmable nanostructures based on ribonucleic acid could be used as vessels for shipping therapeutic molecules into cells, according to US scientists. mark for My Articles similar articles
Chemistry World
November 2006
Bea Perks
Call That Chemistry? This year's Nobel prize in chemistry was a tour de force for crystallography, underscoring the vital role chemistry plays across the sciences. mark for My Articles similar articles
Reactive Reports
Apr/May 2005
David Bradley
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Sarah C.P. Williams
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. mark for My Articles similar articles
Technology Research News
May 5, 2004
Kimberly Patch
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. mark for My Articles similar articles
IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
Chemistry World
October 4, 2006
Bea Perks
Good Year for RNA Roger Kornberg, professor of structural biology at Stanford University, has been awarded the 2006 Nobel prize in chemistry for his work on the molecular basis of transcription. mark for My Articles similar articles
Scientific American
January 2006
Charles Q. Choi
Un-Killing the Messenger Processing bodies do more than serve as RNA trash bins in cells. Research now suggests that these P-bodies are less like junkyards and more like office centers, where messages are amassed, silenced and reactivated. mark for My Articles similar articles
Chemistry World
September 5, 2011
David Bradley
Spiders, Grubbs' and polymer-powered nanomotors A chemical spider that spins a polymer thread using a simple catalyst could drive a nanomotor, according to researchers at Pennsylvania State University, US. mark for My Articles similar articles
Managed Care
November 2003
Thomas Morrow
Making Sense of Antisense and Interference Treatments that interfere with protein synthesis at the cellular level will soon be debated in medical policy committee meetings. mark for My Articles similar articles
Chemistry World
July 17, 2012
Simon Perks
Synthetic nanozymes silence hepatitis C Researchers at the University of Florida, US, have discovered that an artificial nanoparticle complex, known as a nanozyme, can help to treat viral infections by 'shutting off' their genetic material. mark for My Articles similar articles
Chemistry World
January 11, 2008
John Bonner
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. mark for My Articles similar articles
Bio-IT World
December 15, 2004
David A. Bumcrot
Identifying RNAi Drug Candidates Breakthroughs in understanding RNA's extensive role in essential cellular processes have opened up the potential for a whole new class of drugs based on RNAi. mark for My Articles similar articles