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Chemistry World December 18, 2012 Jennifer Newton	Technique to measure chemotherapy effectiveness A technique to measure how effective chemotherapy is by studying the physical changes that occur in human cells has been developed by US scientists.
Chemistry World September 17, 2012 Jennifer Newton	Seeing cells under stress An analytical platform that imposes controlled mechanical strain onto live cells while monitoring changes in cell morphology and molecular signalling has been developed by scientists in Germany.
Chemistry World November 7, 2012 Ian Le Guillou	Coral animal chemical structures solved A combination of atomic force microscopy and computational techniques have been used to solve the unusual structures of two natural products from the Arctic coral-like animal, Thuiaria breitfussi.
HHMI Bulletin Winter 2013 Amber Dance	A Trick of Light When miniSOG protein takes in blue light, it converts ordinary oxygen into a short-lived, excited state called singlet oxygen, which reacts with and changes the molecules around it. The singlet oxygen destroys the mitochondria's delicate machinery.
Chemistry World May 31, 2011 Manisha Lalloo	Hard x-rays to watch chemical reactions Researchers at the ESRF synchrotron at Grenoble, France, produced hard x-rays to look beneath the surface of materials made of lighter elements
Chemistry World September 26, 2006 Fiona Case	Synchronised Delivery for DNA and Drugs Polymer capsules that can simultaneously deliver drug molecules and DNA into a cell could boost the power of cancer treatments.
Chemistry World February 11, 2013 Helen Potter	A new system for cancer detection Cancer cells have been found to differ from normal cells in several ways, including the make up of their cell membranes. Cancer-cell membranes have been found to contain more anionic lipids than normal cells, leading to an overall negatively charged cell surface.
Chemistry World March 8, 2011 Jennifer Newton	Measuring cells' oxygen levels with PEBBLEs Scientists in Germany have developed a strategy to visualise oxygen concentrations in cells to better understand its role in biological reactions such as metabolism.
Chemistry World October 2, 2007 Jonathan Edwards	Light Shed on Parkinson's Culprit European scientists have developed a new technique to detect attogram quantities of iron in living cells -- providing further evidence of the role the metal plays in Parkinson's disease.
Chemistry World November 4, 2011 Phillip Broadwith	Chemists put finger on the trigger to attack cancer Hydrogen peroxide-triggered release mechanisms could help reduce the side effects of cancer drugs by keeping them safely locked up until they reach the oxidizing environment of cancer cells, say scientists in the US.
Chemistry World December 15, 2010 Hayley Birch	New technique probes electron properties of individual atoms A new, low voltage electron microscopy technique allows scientists to discriminate not just between atoms of different elements but between atoms of the same element in different electronic states.
Chemistry World January 2, 2015 Thadchajini Retneswaran	Smart nanoparticles take aim at cancer cells Scientists in China have developed an intelligent nanoparticle system that delivers a chemotherapeutic and radiosensitizer drug directly to the nucleus of cancer cells.
Chemistry World April 8, 2009 Jon Cartwright	Natural biomarker can signal cancer The researchers discovered that cancerous cells contain on average twice as much nicotinamide adenine dinucleotide than normal cells, and that they contain a higher proportion of NADH that is still in the mitochondria and unbound to enzymes.
Chemistry World August 1, 2010 Mike Brown	Snapshots of mystery molecular structures Researchers have used atomic force microscopy to produce clear molecular images that can help determine the correct atomic structure of unknown organic molecules.
Reactive Reports November 2005 David Bradley	Water, Water How a strand of water just a few molecules thick could provide nanoscale clues about water's intriguing properties and why water is the dread enemy of atomic force microscopy.
Chemistry World February 28, 2007 Simon Hadlington	Individual Atoms' Chemical ID Revealed Researchers have demonstrated for the first time that atomic force microscopy can be used to reveal the chemical identity of individual atoms on a surface at room temperature.
Chemistry World February 5, 2009 Simon Hadlington	Carbon nanotube catalysts 'better than platinum' Researchers in the US have developed a novel catalyst based on carbon nanotubes for the electrochemical reduction of oxygen.
Chemistry World October 31, 2012 Ian Le Guillou	A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute.
Bio-IT World July 15, 2003 Julia Boguslavsky	'Fingerprinting' a Single Cell Single-cell proteomics is finally within reach, thanks to a professor of analytical chemistry.
Scientific American January 2009 Charles Q. Choi	Do White Blood Cells Make Cancer Deadly? The ability to spread underlies the killing power of cancer. The process occurs, John Pawelek thinks, when tumor cells fuse with white blood cells -- an idea that, if right, could yield new therapies
Chemistry World February 28, 2014 Tim Wogan	Fuel cells put in the frame with catalysts that need far less platinum US scientists have created an exceptional fuel cell catalyst that contains far less platinum -- conventional catalysts need 36 times more platinum to hit the same levels of activity.
Chemistry World November 17, 2011 Ross McLaren	Giving Fuel Cells a Vitamin Boost Vitamin B12 could replace platinum catalysts in fuel cells as a cheaper alternative.
Smithsonian March 2004	Signal Discovery? A Los Angeles scientist says living cells may make distinct sounds, which might someday help doctors "hear" diseases
HHMI Bulletin February 2011 Sarah C.P. Williams	Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions.
Chemistry World September 30, 2014 Andy Extance	Tiny tips reveal cells' chemical secrets US researchers have broken into individual living cells with inexpensive probes that can suck their contents directly into a mass spectrometer.
Chemistry World May 5, 2011 Simon Hadlington	Revolutionary new single-cell labelling method Researchers in the US and Canada have combined mass spectrometry with a technique called flow cytometry to follow dozens of biochemical markers on individual cells simultaneously.
HHMI Bulletin Aug 2011 Sarah C.P. Williams	The Goldilocks of Cells Too much or too little cell death can lead to disease. Scientists are learning how to find the range that's just right.
Chemistry World August 27, 2015 Matthew Gunther	Nanoscale microscopy casts light on cellular dynamics Scientists at the Howard Hughes Medical Institute, US, have fine tuned an off-shoot of their super-resolution microscopy technique to image dynamic processes within the cell membrane for the first time.
HHMI Bulletin February 2011 Sarah C.P. Williams	Releasing the Brakes on Cell Fate Converting one cell type directly into another is a kind of modern-day alchemy, an ultimate goal in biological research. But unlike turning base metals into gold, changing a cell's identity is feasible, new research shows.
Chemistry World January 11, 2008 John Bonner	DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell.
Chemistry World July 21, 2011 Elinor Richards	Cell Control to Change Cell Function US scientists can now control the reactions occurring inside cells.
Chemistry World September 5, 2013 Emma Stoye	Raman-based imaging takes guesswork out of brain surgery A new technique that color-codes cancerous and healthy brain cells according to their chemistry could help surgeons remove all traces of brain tumors while minimizing damage to sensitive tissues.
Reactive Reports Issue 55 David Bradley	Testing the Byproducts of Cell Death A new approach to testing whether a particular chemotherapy agent is working well in treating a patient's cancer is being developed by UK scientists
Bio-IT World January 21, 2005 Mark D. Uehling	Profiling Drugs via Microscopy With robotic equipment, this Harvard team scans cells faster than researchers can blink their eyes.
Chemistry World March 16, 2009 Hayley Birch	Nanodumbbells Target Cancer Cells US scientists have designed nanoparticles that function like 'guided missiles' in the targeted destruction of breast cancer cells.
Chemistry World October 7, 2012 David Bradley	Magnetic nanoparticles zap cancer Nanoparticles can be used as a remote-controlled magnetic death switch to kill cancer cells, according to researchers from Korea.
Bio-IT World July 2005 David M. Evans	Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior.
Chemistry World August 2, 2011 Kate McAlpine	Hacking into chemical cell phone calls US researchers have made a nanodevice that can eavesdrop on a cell's mutterings, and they say it could be adapted to listen in on conversations between cells.
Chemistry World March 7, 2012 Phillip Broadwith	Polymer thermometer picks out cell's hotspots Mapping the temperature differences in different portions of living cells is now possible thanks to a fluorescent polymer thermometer developed by Japanese scientists.
Chemistry World November 7, 2012 Simon Hadlington	World's first all-carbon solar cell Researchers in the US and China have built a photovoltaic cell made entirely from carbon. The electrodes and light-active layers are made from a combination of three carbon allotropes -- nanotubes, fullerenes and graphene.
Chemistry World October 23, 2014	The resolution revolution Super-resolution fluorescence microscopy earned three of its creators a Nobel prize this year.
Chemistry World September 10, 2008 Simon Hadlington	Failed anxiety drug could treat cancer Scientists believe they have solved the mystery of how a drug originally developed for treating anxiety can kill cancer cells.
Chemistry World October 31, 2010 Michael Gross	Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body.
Reactive Reports David Bradley	Nanotechnology Sticks its Neck Out An unexpected finding by a team of physicists and biologists could become instrumental in making nanoscale materials with a range of applications in gene and drug delivery, enzymatic synthesis, and encapsulation systems for biosensors as well as optoelectronic components.
Chemistry World July 28, 2009 Michael Gross	DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise.
Chemistry World September 18, 2006 Michael Gross	Iron Chelates Beat Cancer Cancer cells need more iron than normal body cells to sustain their abnormally rapid growth. Researchers have now identified one particularly potent chelate complex that helps deplete tumors of iron.
Chemistry World June 9, 2008 Simon Hadlington	Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes.
Chemistry World April 10, 2008 Sarah Houlton	Radiotherapy Side-Effects Suppressed A new drug being developed by scientists at Cleveland BioLabs (CBLI) in the US may hold the key to protecting healthy cells from the effects of radiotherapy during cancer treatment.
Technology Research News May 4, 2005 Eric Smalley	Chip Gauges Cell Reactions Researchers have devised a way to test within minutes the reactions of cells to all types of stimuli. The researchers' system is very sensitive, relatively inexpensive, uses little power, and is portable.
Chemistry World March 10, 2011 Elinor Richards	3D model to study breast cancer Scientists from the US have made a computational model of the formation of breast acini, the sac-like part of the milk-producing glands, to understand complex events occurring during the progression of breast cancer.