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Chemistry World
July 22, 2015
Judy Hayler
The handbook of medicinal chemistry: principles and practice The handbook of medicinal chemistry: principles and practice guides the reader through the R&D process from target validation to late stage clinical trials, via a series of chapters written by individuals in industry and academia. mark for My Articles similar articles
Chemistry World
November 18, 2014
Katrina Kramer
Molecules: the elements and the architecture of everything Molecules is a serious attempt to explain the world of chemical compounds to the reader without assuming previous science knowledge. mark for My Articles similar articles
Chemistry World
August 15, 2013
Lorenzo Caggiano
An introduction to medicinal chemistry (5th edition) An introduction to medicinal chemistry, by Graham Patrick, is exactly that and more. It is an essential text aimed at undergraduates and postgraduates studying aspects of medicinal chemistry. mark for My Articles similar articles
Chemistry World
December 17, 2012
Patrick Walter
RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists. mark for My Articles similar articles
Chemistry World
August 2009
Derek Lowe
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder mark for My Articles similar articles
Chemistry World
May 13, 2015
Stephen McCarthy
Venoms to drugs: venom as a source for the development of human therapeutics The book is well-constructed, starting with an overview of the evolutionary origins of venoms and how these relate to common structures, followed by a guide to modern bioinformatics methods and their application to research in this field. mark for My Articles similar articles
Chemistry World
December 2008
Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project. mark for My Articles similar articles
Chemistry World
February 8, 2006
Jon Evans
To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space. mark for My Articles similar articles
Chemistry World
May 3, 2013
Alison Rodger
VCD spectroscopy for organic chemists I highly recommend VCD Spectroscopy, by Philip Stephens and others, for organic chemists as the textbook of choice on this useful topic. mark for My Articles similar articles
Chemistry World
December 2007
Derek Lowe
Column: In the Pipeline The challenge of biologics. mark for My Articles similar articles
Chemistry World
June 23, 2015
Derek Lowe
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Chemistry World
August 28, 2012
Jessica Gwynne
Bridging the gap Orbital Approach to the Electronic Structure of Solids builds on a book originally published by two of the authors in French in 1997. mark for My Articles similar articles
Chemistry World
June 2010
Column: In the pipeline Derek Lowe looks into his crystal ball to see what the future of medicinal chemistry might be mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
Chemistry World
September 11, 2012
Maria Burke
Orphan drugs set for 'tremendous growth' A new report by Thomson Reuters offers clear confirmation that developing drugs for rare, or orphan, diseases is economically attractive, despite the smaller patient pool. mark for My Articles similar articles
The Motley Fool
October 9, 2006
Brian Lawler
The Commandments of Biotech Investing, Part 2 It's a complex field, but it's not impossible for investors to master. The more in-depth your research of a potential biotech investment, and the more you remember to follow these commandments, the better your potential for success will be when investing in this fascinating field. mark for My Articles similar articles
Chemistry World
May 20, 2015
Katrina Kramer
Molecules that amaze us For chemistry-savvy readers, the book is an enjoyable, easy-to-digest collection of fascinating molecules to dip in and out of. mark for My Articles similar articles
Chemistry World
November 6, 2009
Phillip Broadwith
Enzyme binds both sides of the mirror European chemists have discovered that both mirror-image forms of a particular compound can bind at the same time in the same site of an enzyme, a phenomenon that has never been seen before. mark for My Articles similar articles
Chemistry World
July 25, 2008
Olivia Walker
Engineered antibodies could cut chemotherapy risks US scientists have cut the side-effects of cancer treatment in animal trials by carefully controlling the number of drug molecules attached to the antibodies used for chemotherapy. mark for My Articles similar articles
The Motley Fool
September 23, 2008
Brian Lawler
Will Generic Biologics Get Special Treatment? While the rest of the market was lost in the financial meltdown, a little-noticed report discussing some of the biopharmaceutical bills going through Congress was released. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
April 2011
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good. mark for My Articles similar articles
Chemistry World
August 13, 2015
Exploiting the data mine Chemists must embrace open data to allow us to collectively get the best out of the masses of new knowledge we unearth, reports Clare Sansom mark for My Articles similar articles
Pharmaceutical Executive
September 1, 2008
Jeffrey S. Aronin
The Orphan Opportunity The Orphan Drug Act was passed 25 years ago. But the challenge of actually getting rare disease drugs and therapies to patients still remains mark for My Articles similar articles
The Motley Fool
September 21, 2006
Jack Uldrich
Harris & Harris Looks to Separate New technology could lead to safer, more effective drugs. Because of proprietary reasons, it's unlikely that ENS will be able to publicly announce when Big Pharma companies have licensed its technology, but Harris & Harris investors have reason to be optimistic. mark for My Articles similar articles
Chemistry World
June 11, 2014
Andrew Benniston
Electrons in molecules: from basic principles to molecular electronics The material provided by Jean-Pierre Launay and Michel Verdaguer is ideal for those wanting to know about the topic of electrons in molecules. mark for My Articles similar articles
Chemistry World
April 9, 2009
Phillip Broadwith
Dual-action malaria drug reverses resistance US chemists have designed a new class of antimalarial drug that can reverse the malaria parasite's resistance to existing drugs. mark for My Articles similar articles
Pharmaceutical Executive
November 1, 2006
Thoughtleader: Making Things Stick Ambrx has created the "glue" that allows researchers to attach activity-enhancing molecules to amino acids where they couldn't before. mark for My Articles similar articles
Technology Research News
March 23, 2005
Nanowires track molecular activity Researchers from Harvard University have found a way to use transistors made from silicon nanowires to gain information about how small molecules bind to proteins. mark for My Articles similar articles
Pharmaceutical Executive
September 1, 2011
Jill B. Conner
Complex Biologics: The View from Teva Industry and regulators alike must grapple with the sensitivities associated with developing bio-similar drugs. mark for My Articles similar articles
Chemistry World
January 2011
Column: In the pipeline Some medicinal chemists can't get enough fluorines in their molecules. The love-hate relationship is explained. mark for My Articles similar articles
Managed Care
September 2004
Thomas Morrow
Orphan Drug Act Treatments Deserve Full Insurance Coverage An important federal law encourages development of drugs for populations so small that the market would otherwise ignore them. Should they not then be covered? mark for My Articles similar articles
Chemistry World
September 29, 2015
Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make? mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Technology Research News
December 3, 2003
Molecule does two-step Duke University researchers have found a way to make a molecule react only when it has been hit by two photons of ultraviolet light, making the molecule a controllable switch. The molecule could eventually be used in optical storage devices and in biochips. mark for My Articles similar articles
Chemistry World
June 14, 2012
Nina Notman
A celebration of chemistry Simon Cotton's latest book, Every Molecule Tells a Story, is -- in his own words -- 'a celebration of molecules and of chemistry' aimed at school and university students, and their teachers. mark for My Articles similar articles
Chemistry World
November 27, 2013
Derek Lowe
Rolling boulders uphill A lot of preclinical projects don't even get off the ground, and many that do still never deliver anything to the development groups. mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
Technology Research News
November 5, 2003
Paired molecules store data Researchers from the University of California at Irvine have bonded a pair of molecules to form a molecule that has two states. The components are photochromic fulgimide and a dye molecule capable of florescence. mark for My Articles similar articles
Managed Care
April 2007
Martin Sipkof
Abbreviated Approval Process In the Works for 'Biosimilar' Drugs The Access to Life-Saving Medicine Act may be a first step to giving the FDA the legal authority to approve these drugs. mark for My Articles similar articles
CIO
December 1, 2002
Sarah D. Scalet
When Every Molecule Counts A group of electrical engineers at Purdue University hope that their research could lead to ultrasensitive sensors capable of detecting a single molecule of a biological agent or chemical pollutant. mark for My Articles similar articles
Chemistry World
March 12, 2015
Matthew Gunther
Chemical building blocks produce a wellspring of organic molecules Scientists in the US have developed an automated platform to create small organic molecules from a set of simple of chemical building blocks. mark for My Articles similar articles
Chemistry World
July 3, 2014
Tami Spector
Of atoms and aesthetics Molecular aesthetics means many things to a few people. For some it means tangible aspects of compounds; for others yet, the ways that chemists represent molecules. mark for My Articles similar articles
Pharmaceutical Executive
September 1, 2005
Parker & Amar
Building Blockbusters The most lucrative new drugs are often less glamorous than first-in-class new molecular entities. And they are much less risky. mark for My Articles similar articles
Chemistry World
March 9, 2006
Katharine Sanderson
Covalent Bonds Crack Under the Strain Chemists must consider engineering principles when designing molecules following news that tough carbon-to-carbon bonds break easily under mechanical strain. mark for My Articles similar articles
Chemistry World
October 12, 2011
Joanne Thomson
Hot Chemistry Temperature played a crucial role in David MacMillan's decision to study chemistry. mark for My Articles similar articles
Chemistry World
October 15, 2008
Simon Hadlington
Long-life light illuminates cells The new dye, based on platinum, will carry on emitting light long after any interfering 'autofluorescence' from naturally occurring molecules in the cell has fizzled out. mark for My Articles similar articles
The Motley Fool
March 3, 2009
Brian Orelli
Stop Worrying About Follow-On Biologics They're inevitable, but they won't hurt biotech as much as you might think. mark for My Articles similar articles
Chemistry World
January 19, 2010
Simon Hadlington
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions. mark for My Articles similar articles