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Chemistry World June 18, 2015 Emma Stoye |
Crowdsourcing compounds to tackle antibiotic resistance Chemists around the world are being called on to donate samples of novel compounds they have synthesized to a crowdsourcing project that aims to find new antibiotics. |
Chemistry World September 24, 2013 Jennifer Newton |
Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products. |
Bio-IT World October 10, 2003 |
Diving for Ocean Genomes The race to preserve genetic treasures is getting help from genomics. |
Reactive Reports Issue 30 David Bradley |
Marine bugs make drugs William Fenical of the Scripps Institution in La Jolla and his colleagues have discovered a new source of potential drugs -- actinomycetes living in tropical and subtropical ocean sediments. Like their soil-dwelling cousins, the marine actinomycetes produce highly active substances. |
Chemistry World April 3, 2008 Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Chemistry World December 17, 2012 Patrick Walter |
RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists. |
Chemistry World August 31, 2012 Simon Hadlington |
'Ocean methane paradox' solved? Numerical simulation of methane production by methanogenic microorganisms suggests that up to 400 billion tonnes of methane could be sitting under the ice. If the ice sheet collapses due to a warming climate, this could release the gas, which in turn would increase warming, the researchers say. |
Chemistry World December 6, 2013 Julianne Wyrick |
Crowdsourcing unearths promising anticancer compound Crowdsourcing soil from across the US turned up some interesting fungi with promising medicinal molecules. |
Geotimes December 2004 Sara Pratt |
Acidic Waters Threaten Sea Life High acidity in the world's oceans may be threatening coral populations, such as those in the Florida Keys National Marine Sanctuary. |
Chemistry World March 2006 Katie Gibb |
Extreme Analysis High pressures, cold temperatures and inaccessible samples all make analytical work challenging for chemists. Science still has a lot to gain from studying and working in extreme environments. |
Chemistry World April 27, 2011 Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
Chemistry World February 2, 2007 Jessica Ebert |
Bacterial Gene Generates Seaside Smell Researchers have identified a bacterial gene that is needed for the production of dimethyl sulfide, the climate-cooling gas responsible for the distinctive smell of the seaside. The discovery challenges the current hypothesis for the mechanism involved in the synthesis of DMS. |
Bio-IT World January 21, 2005 Mark D. Uehling |
How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis. |
Chemistry World August 13, 2015 |
Exploiting the data mine Chemists must embrace open data to allow us to collectively get the best out of the masses of new knowledge we unearth, reports Clare Sansom |
HHMI Bulletin Nov 2010 Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Searcher Nov/Dec 2003 David Mattison |
Information on the Seven Seas: International Ocean Science Web Resources (Part 2) A look at three areas of international cooperation in ocean science research: the physical and chemical ocean, meteorology, and marine life. |
Geotimes May 2004 David Lawrence |
New Centers for Ocean and Health Research The National Science Foundation (NSF) and the National Institute of Environmental Health Sciences (NIEHS) recently announced funding for four joint research centers to conduct basic research into how marine phenomena may harm or enhance people's health. |
Chemistry World January 28, 2009 Nina Notman |
Iron helps oceans capture more carbon A team of international scientists studying the role of iron in the storage of carbon under the ocean have confirmed that natural iron fertilisation increases the rate of carbon capture. |
Chemistry World September 11, 2013 Andria Nicodemou |
Bacteria incriminated by their odor Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. |
Chemistry World December 4, 2009 Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Food Processing March 2009 Diane Toops |
Kraft Foods Global Thinks Outside the Box with Bioactive Ingredients Kraft hires a pharmaceutical company to help it develop functional foods. |
Chemistry World September 27, 2007 Simon Hadlington |
Scientists Uncover How Last Ice Age Ended Scientists have shown that the end of the last age 19,000 years ago began in the higher latitudes of the southern hemisphere before sweeping into the tropics. |
Chemistry World September 12, 2006 Mark Peplow |
Bacteria Silenced by Conversation Stoppers Molecules that interrupt the chemical conversations of bacterial communities are showing early promise in beating the bugs. |
Chemistry World April 2011 |
Column: In the Pipeline If you look over the whole pharmacopeia, you'll see there are a lot of compounds that got their start as natural products. |
Pharmaceutical Executive February 1, 2006 Ron Feemster |
Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets. |
Geotimes April 2003 Christina Reed |
The mighty, tiny larvae Understanding that marine larvae play a more active role in the ocean processes and have perhaps an evolutionary history of staying close to home provides impetus for shoreline communities to protect local habitats. |
Chemistry World March 5, 2015 Emma Stoye |
Forgotten synthetic PhD theses set to be given new lease of life A team of researchers have amassed a digital collection of more than 75,000 compounds from PhD theses that might otherwise have mouldered in obscurity. |
Smithsonian March 2004 Lawrence M. Small |
From the Secretary - World View Panama offers an ideal vantage point for scientists to see the big picture of life on earth. The forests and coral reefs of the tropics are the world's most biologically diverse ecosystems. |
Chemistry World August 28, 2007 Tom Westgate |
Repairing DNA Could Let Frozen Bacteria Survive for Millennia An international team of scientists believe they have strong evidence that bacteria trapped in permafrost are able to survive for hundreds of thousands of years by repairing their DNA. |
Chemistry World December 16, 2013 Anthony King |
Database of 15 million chemical structures set free A collection of over 15 million chemical structures from patents -- SureChem -- is to be made freely available through the European Bioinformatics Institute. |
Chemistry World March 26, 2013 |
Germany, China create nanotech center Researchers in Germany and China have founded a new nanotechnology and biomedicine center to develop new materials, focusing on developing regenerative treatments for bone diseases. |
Chemistry World February 15, 2006 Simon Hadlington |
Pharmaceutical Promise in the Desert Two molecules that inhibit a protein linked to cancer pathogenesis have been discovered in the Arizona desert. |
Chemistry World February 4, 2009 Nina Notman |
Marine sponges show their age Whilst searching for oil, a team of international scientists have found something completely different -proof that animal life existed more than 635 million years ago. |
Chemistry World February 22, 2010 Hayley Birch |
Soil switches on antibiotic genes in bacteria So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown. |
Chemistry World July 15, 2010 Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Science News June 28, 2003 |
TimeLine: June 24, 1933 Lightning, most awesome of the spectacular forces of nature, has yielded some of its mystery to science... Electric current untangles salt and paint on old vases... Sea water nitrates increased by unknown "something" |
Chemistry World March 6, 2013 Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Bio-IT World June 17, 2004 John Garvey |
Rational Decisions As companies in the computationally guided rational drug design sector mature, they should be more sure of the boundaries that surround their proprietary technologies. |
Popular Mechanics January 2009 Michael Milstein |
World's Hardiest Organisms to Face 3 Years in Space When a Russian spacecraft sets off late this year to scrape samples of the Martian moon Phobos, at least 10 of Earth's toughest life-forms will be going along for the ride. |
Chemistry World June 2011 |
Column: In the pipeline Chemists are human. Humans are hierarchical. Therefore...well, therefore, you'll find a number of different roles and levels for scientists in a drug company's labs. Here's a rough ordering, from least experienced to most. |
Scientific American November 14, 2005 Gunjan Sinha |
Bugs and Drugs Gut bacteria could determine how well medicines work. |
Fast Company September 2001 Fara Warner |
Where Is the Next Frontier of Innovation? Fast-paced experimentation. Distributed intelligence. Total teamwork. The scientific formula behind the new economy is still disrupting the status quo -- in this case, 20,000 leagues under the sea... |
Chemistry World June 2008 Sarah Houlton |
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success |
Chemistry World January 2012 |
Column: In the pipeline Derek Lowe discusses how companies are increasingly trying to do more with the compounds they already know a lot about |
Chemistry World February 24, 2010 Hayley Birch |
Marine microbes wired up A new study provides evidence for the existence of naturally occurring electric circuits orchestrated by marine bacteria. |
Chemistry World August 2009 Derek Lowe |
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder |
Chemistry World July 8, 2008 Hayley Birch |
Yellow Fever Mosquito Takes Chemical Cues From Bacteria Bacterial chemicals that encourage female mosquitoes to lay eggs could help to stem the spread of mosquito-borne diseases like dengue and yellow fever, according to US scientists. |
Chemistry World December 18, 2007 Victoria Gill |
Seeds of Doubt A company called Planktos plans to dump 50-100 tons of iron sulfate into a patch of ocean 100km wide in a bid to seed the growth of plankton. |
IEEE Spectrum August 2010 Paul McFedries |
Technically Speaking: Hacking the Planet There's plenty of controversy swirling around the idea of climate intervention -- and no shortage of new words |
Chemistry World January 31, 2008 Richard Van Noorden |
Ocean Hydrocarbons Made From Rocks Researchers investigating 60-meter high carbonate chimneys in the Atlantic Ocean have discovered that hydrocarbons seeping out from the vents don't come from a biological source such as bacteria, plants or animal matter. |