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Chemistry World September 11, 2013 Andria Nicodemou |
Bacteria incriminated by their odor Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. |
Chemistry World July 28, 2008 Hayley Birch |
Biofilms deploy chemical weapons When marine bacteria join together in sticky biofilms, they produce lethal chemicals to protect themselves from predators. |
Scientific American May 2009 Melinda Wenner |
Quiet Bacteria and Antibiotic Resistance Bacteria devoted to growth instead of "quorum sensing" communication could beat antibiotic resistance. |
Chemistry World May 20, 2015 Katrina Kramer |
Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs. |
Chemistry World December 4, 2009 Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Chemistry World August 27, 2014 Hayley Simon |
Ionic liquids join battle against antibiotic resistance US researchers have used ionic liquids -- organic salts that are liquid at room temperature -- to disrupt bacterial biofilms and deliver antibiotics through the skin's outer layer. |
HHMI Bulletin Nov 2010 Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Fast Company May 2009 Elizabeth Svoboda |
Biotechs Wage War on Superbugs With antibiotic resistance on the rise, three biotechs are developing new ways to wage war on superbugs. |
Chemistry World May 31, 2009 Nina Notman |
The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used. |
Chemistry World October 8, 2013 David Bradley |
3D printing bacteria Jason Shear and colleagues at the University of Texas, US, have developed a 3D printing technique that lets them 'construct' defined bacterial communities so that short-range chemical communications and physical interactions between bacteria can be investigated more systematically than ever before. |
Chemistry World August 6, 2007 Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
Chemistry World October 4, 2012 Emma Eley |
Bacterial growth is inhibited by broccoli Chemists from Israel say that the isothiocyanates sulforaphane and erucin, found in brassicaceae vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower, inhibit growth of the disease-causing bacteria Pseudomonas aeruginosa. |
Chemistry World January 8, 2015 Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World May 6, 2014 Andy Extance |
WHO raises alarm on deadly bacteria The World Health Organization has warned antibiotic resistant bacteria could bring a nightmarish future, where seemingly trivial scrapes turn lethal, and currently routine operations become too risky to contemplate. |
Chemistry World March 19, 2007 Lionel Milgrom |
Gallium-Based Antimicrobials Antibiotic-resistant bacteria can be killed with gallium. US researchers used gallium as a 'Trojan horse' to fool bacteria into thinking they were feeding on iron. Bacteria need iron to survive, but they cannot distinguish between iron and gallium. |
Chemistry World July 1, 2013 James Urquhart |
Antibiotic research hits a sweet spot UK researchers have found a way to weaken the molecular armour of Escherichia coli to allow the host's immune system to attack and kill the pathogen. |
Chemistry World August 11, 2011 Hayley Birch |
'Dial a Molecule' Approach Controls Antibiotic Production Scientists have used genetic methods to control the chemical structures of pacidamycin antibiotics produced in bacteria. Their approach allows them to 'dial into' particular molecules, and to generate new pacidamycins. |
Reactive Reports March 2005 David Bradley |
Microbial Manufacturing A bacterium is a microscopic chemical factory producing antibiotics, immunosuppressants, and anticancer drugs no chemist can synthesize. but pharmaceutical companies have been tapping into microbial drug manufacturing for some time. |
Chemistry World April 4, 2011 Carol Stanier |
Mighty micelles that make themselves Scientists in the US and Singapore have made self assembling micelles of cationic polymers that kill bacteria but are biodegradable - raising further hope of a nanotechnology solution to the problem of antibiotic resistance. |
Chemistry World February 19, 2013 Ian Farrell |
Analyzing bacterial metabolites A mass-spectrometry technique that can characterize and spatially resolve the metabolites produced by bacteria could lead to a better understanding of how different microbes interact with each other, and how their chemistry could be harnessed industrially. |
Chemistry World February 2, 2007 Jessica Ebert |
Bacterial Gene Generates Seaside Smell Researchers have identified a bacterial gene that is needed for the production of dimethyl sulfide, the climate-cooling gas responsible for the distinctive smell of the seaside. The discovery challenges the current hypothesis for the mechanism involved in the synthesis of DMS. |
Chemistry World December 7, 2012 Lucy Gilbert |
Bactericides reach new depths Scientists in the US and China have come up with a low-risk treatment for bacterial infections in a deep wound. |
Chemistry World May 6, 2015 Matthew Gunther |
Zombie cells may rise up to kill infections The worst fears of Hollywood may yet become a reality as chemists in Israel have found dead bacteria, killed with silver, may be able rise up like 'zombies' and go on to kill surviving pathogens. |
Chemistry World May 12, 2011 Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
Chemistry World April 3, 2008 Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Chemistry World February 9, 2012 Jennifer Newton |
A new generation of tuberculosis drugs Scientists in India are targeting enzymes responsible for catalysing the formation of bonds to repair nicks in the phosphodiester backbone of DNA - called DNA ligases - to tackle the ever-growing health concern of multi-drug resistant bacteria. |
Chemistry World December 10, 2013 Jonathan Wells |
Disarming bacteria to beat infection Researchers in Germany looking to find unprecedented ways of combating bacterial infection have demonstrated that certain small molecules can reduce the ability of Staphylococcus aureus to cause disease. |
Chemistry World March 6, 2013 Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World February 22, 2010 Hayley Birch |
Soil switches on antibiotic genes in bacteria So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown. |
Chemistry World September 24, 2015 Harriet Brewerton |
Antibiotics pit against bacterial biofilms Scientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics. |
Chemistry World April 27, 2011 Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
AskMen.com Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Chemistry World November 5, 2013 Emma Stoye |
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. |
Bio-IT World January 21, 2005 Mark D. Uehling |
How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis. |
Chemistry World December 15, 2015 Michaela Muehlberg |
Bacterial identification gets a culture shock Scientists in the UK have developed a new tool to distinguish bacterial strains from each other. |
Chemistry World September 19, 2008 John Bonner |
Filling the antibiotic gap Resistance to currently available antibacterial drugs is causing growing concern among doctors who find themselves unable to treat common infections |
Nutrition Action Healthletter May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
Chemistry World July 6, 2006 Michael Gross |
Insecticide Simplified A rapid, flexible way to make variants of potent insecticide molecules known as spinosyns could help to combat the growing problem of insect resistance, according to German chemists. |
Wired May 22, 2009 Erin Biba |
New Germ Busters Outwit Antibiotic-Resistant Bacteria Researchers are testing new bug-killers that bypass the molecular pathways used by old-school antibiotics. |
Chemistry World January 30, 2015 Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Chemistry World August 13, 2012 Anthony King |
Non-stick coating gives biofilms the slip A new class of material has been created that bacteria find incredibly hard to stick to. An estimated 80% of infections acquired in hospitals involve sticky biofilms of bacteria that build up on surfaces and it is challenging is to reduce their growth on medical devices, such as catheters. |
Chemistry World January 3, 2012 Simon Hadlington |
One-pot synthesis creates anticancer candidates Researchers in Germany have developed a simple, rapid and high-yielding cascade synthesis of a collection of polycyclic compounds that resemble indole alkaloid natural products and which interfere with cell division. |
Chemistry World September 15, 2013 Andy Extance |
Light-switch antibiotics could undermine resistance Dutch chemists have made a new weapon to fight bacteria: an antibiotic whose microbe-killing activity they can turn on using ultraviolet light, before it slowly diminishes. |
Chemistry World April 4, 2007 John Bonner |
Antibiotic Combinations Tackle Resistance Using combinations of certain antimicrobial compounds can favor the growth of non-resistant strains of bacteria at the expense of resistant ones. The surprising finding may provide a general strategy to help eradicate strains of bacteria that are resistant to antibiotic therapy. |
AskMen.com Jacob Franek |
Superbugs So long as antibiotic use remains widespread and excessive, superbug bacteria will be here with us. Read on about some of the most common North American superbugs. |
Chemistry World January 20, 2014 Martha Henriques |
Fast test classifies meningitis bacteria Researchers in the UK have developed a new method that uses surface enhanced Raman scattering to quickly identify which meningitis causing bacteria is responsible for an infection. |
Chemistry World March 13, 2013 Ned Stafford |
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. |
Wired September 25, 2007 |
Three Smart Things You Should Know About Bacteria The benefits of bacteria. |
Chemistry World February 27, 2013 Anthony King |
PharmaSea to scour ocean depths for new drugs A new project will soon see scientists trawling the ocean bottoms for new bioactive compounds. Scientists on the PharmaSea mission will haul samples of mud and sediment from the deep sea, isolating marine organisms in the hunt for novel drug candidates. |
Chemistry World January 10, 2010 Simon Hadlington |
Antibiotic decay products reverse resistance In a colony of bacteria living in the presence of an antibiotic in natural environments, individuals that are sensitive to the antibiotic can co-exist with those that are resistant, whereas logic would dictate that only resistant bacteria should survive. |