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Chemistry World
March 19, 2007
Lionel Milgrom |
Gallium-Based Antimicrobials Antibiotic-resistant bacteria can be killed with gallium. US researchers used gallium as a 'Trojan horse' to fool bacteria into thinking they were feeding on iron. Bacteria need iron to survive, but they cannot distinguish between iron and gallium.   |
Chemistry World
June 28, 2013
Emma Stoye |
Antibiotic killing mechanism debate continues Antibiotics can kill bacteria without the need for reactive oxygen species. That's the claim of new research, which has added new evidence into the emerging debate over how antibiotics exert their lethal effects. |
Chemistry World
April 4, 2007
John Bonner |
Antibiotic Combinations Tackle Resistance Using combinations of certain antimicrobial compounds can favor the growth of non-resistant strains of bacteria at the expense of resistant ones. The surprising finding may provide a general strategy to help eradicate strains of bacteria that are resistant to antibiotic therapy. |
AskMen.com
Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Bio-IT World
January 21, 2005
Mark D. Uehling |
How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis. |
Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World
April 27, 2011
Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Chemistry World
July 15, 2010
Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Chemistry World
November 5, 2013
Emma Stoye |
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
Chemistry World
January 3, 2013
Andrew Turley |
TB drug milestone for bedaquiline Bedaquiline (sirturo) has become the first drug to be approved in the US for the treatment of multi-drug resistant tuberculosis |
Chemistry World
December 4, 2009
Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Chemistry World
March 6, 2013
Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World
January 10, 2010
Simon Hadlington |
Antibiotic decay products reverse resistance In a colony of bacteria living in the presence of an antibiotic in natural environments, individuals that are sensitive to the antibiotic can co-exist with those that are resistant, whereas logic would dictate that only resistant bacteria should survive. |
Chemistry World
March 19, 2014
Emma Stoye |
Molecular drill bits attack tuberculosis Peptides that punch through bacterial cell walls while leaving human cells unharmed could open up new ways to tackle antibiotic resistance, say researchers in the US. |
Chemistry World
August 6, 2007
Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
American Family Physician
March 15, 2001
Thomas Hooton & Stuart Levy |
Antimicrobial Resistance: A Plan of Action for Community Practice Antibiotic resistance was once confined primarily to hospitals but is becoming increasingly prevalent in family practice settings, making daily therapeutic decisions more challenging. |
Chemistry World
March 13, 2013
Ned Stafford |
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. |
AskMen.com
Jacob Franek |
Superbugs So long as antibiotic use remains widespread and excessive, superbug bacteria will be here with us. Read on about some of the most common North American superbugs. |
Chemistry World
September 11, 2013
Andria Nicodemou |
Bacteria incriminated by their odor Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. |
Chemistry World
May 6, 2014
Andy Extance |
WHO raises alarm on deadly bacteria The World Health Organization has warned antibiotic resistant bacteria could bring a nightmarish future, where seemingly trivial scrapes turn lethal, and currently routine operations become too risky to contemplate. |
Nutrition Action Healthletter
May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
Chemistry World
February 12, 2015
Dinsa Sachan |
Target ignorance to tackle resistance After the discovery of the New Delhi metallo-beta-lactamase-1 (NDM-1) gene, which renders some bacteria resistant to most antibiotics, India has attracted global criticism for not being able to contain antibiotic resistance. |
Mother Jones
December 2000
Edwin Dobb |
Growing Resistance Is agribusiness squandering one of medicine's most potent weapons? |
Chemistry World
September 17, 2009
Simon Hadlington |
Targeted TB treatment Researchers in the US have discovered that a class of small molecules can selectively disable a key protein complex in the tuberculosis bacterium and kill the organism |
Chemistry World
March 8, 2013
Simon Hadlington |
Battleground develops over antibiotic killing mechanism Two recent papers will require many in the field to re-examine and re-open the question of whether or not several different classes of bactericidal antibiotics do or do not work through a common mechanism. |
Chemistry World
June 18, 2015
Emma Stoye |
Crowdsourcing compounds to tackle antibiotic resistance Chemists around the world are being called on to donate samples of novel compounds they have synthesized to a crowdsourcing project that aims to find new antibiotics. |
Chemistry World
May 12, 2011
Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
Chemistry World
September 24, 2015
Harriet Brewerton |
Antibiotics pit against bacterial biofilms Scientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics. |
Chemistry World
January 30, 2015
Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
American Family Physician
December 15, 2000 |
Antibiotics: When They Can and Can't Help Antibiotics are strong medicines that can stop some infections and save lives. When they aren't used the right way, antibiotics can cause more harm than good. You can protect yourself and your family by knowing when you should use antibiotics and when you should avoid them... |
Chemistry World
February 6, 2013
Harriet Brewerton |
Diagnosing bacterial growth Antibiotics are used regularly for treating bacterial infections, but there is currently no quick and simple test to determine the most effective type or dose of antibiotic for a specific patient infection. |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
Chemistry World
August 15, 2012 |
The latent threat of tuberculosis Although TB was close to being eradicated in the developed world, it is a major problem in developing countries. With drug-resistant strains on the increase, Clare Sansom outlines the latest in the fight against this killer disease |
Pharmaceutical Executive
July 30, 2007
Sarah Houlton |
Global Report: Make Resistance Futile Patients are losing the battle against bacteria. Can pharma be convinced to swing the sword of new antibiotic development? |
American Family Physician
September 15, 2001
Richard Colgan & John H. Powers |
Appropriate Antimicrobial Prescribing: Approaches that Limit Antibiotic Resistance Physicians should be familiar with the clinical situations in which they should provide antibiotics and those in which they may safely be withheld... |
Science News
June 28, 2003
Ben Harder |
McDonald's Cutback in Antibiotics Use Could Reduce Drug-Resistant Bacteria The fast-food chain McDonald's announced on June 19 that it will stop its farms under contract from feeding chicken, cattle, and pigs certain antibiotics intended to accelerate the animals' growth. That step might slow or reverse the rise of antibiotic-resistant bacteria that can infect people. |
American Family Physician
January 15, 2004 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics work against all infections?... What is "antibiotic resistance"?... Why should I worry about antibiotic resistance?... How do I know when I need antibiotics?... How should I take the antibiotics that my doctor prescribes?... etc. |
American Family Physician
September 15, 2006 |
When Antibiotics Can Help A consumer's guide: What are antibiotics?... How do antibiotics work?... What is antibiotic resistance?... How can I prevent antibiotic resistance?... |
American Family Physician
March 15, 2001 |
Avoiding Resistance to Antibiotics-- When Do I Need an Antibiotic? When bacteria are exposed to the same antibiotics, after a while the antibiotic can't fight the germs anymore... |
American Family Physician
October 1, 2006 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics always work?... What is bacterial resistance?... What can I do to help myself?... etc. |
Managed Care
June 2004
Jack McCain |
Health Plans Respond as Microbes Develop Resistance Techniques Managed care is having some success discouraging practices that promote the development of "superbugs." |
Wired
September 25, 2007 |
Three Smart Things You Should Know About Bacteria The benefits of bacteria. |
HHMI Bulletin
Feb 2012
Nancy Ross-Flanigan |
A Safer Shot at TB While trying to understand tuberculosis bacteria genes, researchers discovered a safe way to shut down the bacteria. |
Chemistry World
July 8, 2014
Anthony King |
Call for new models to pay for antibiotics Governments will need to think seriously about changing the way they pay for the drugs. That's the conclusion of a report from the UK House of Commons science and technology committee. |
