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Chemistry World
June 28, 2013
Emma Stoye |
Antibiotic killing mechanism debate continues Antibiotics can kill bacteria without the need for reactive oxygen species. That's the claim of new research, which has added new evidence into the emerging debate over how antibiotics exert their lethal effects.   |
Chemistry World
November 5, 2013
Emma Stoye |
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. |
Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World
May 12, 2011
Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
AskMen.com
Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Chemistry World
December 4, 2009
Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Chemistry World
March 8, 2007
Simon Hadlington |
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. |
Chemistry World
January 10, 2010
Simon Hadlington |
Antibiotic decay products reverse resistance In a colony of bacteria living in the presence of an antibiotic in natural environments, individuals that are sensitive to the antibiotic can co-exist with those that are resistant, whereas logic would dictate that only resistant bacteria should survive. |
Chemistry World
October 13, 2006
Richard Van Noorden |
Fastest Synthesis in the West A promising antibiotic with a novel mechanism of action has been synthesized for the first time -- and with impressive speed. |
Chemistry World
March 19, 2014
Emma Stoye |
Molecular drill bits attack tuberculosis Peptides that punch through bacterial cell walls while leaving human cells unharmed could open up new ways to tackle antibiotic resistance, say researchers in the US. |
Chemistry World
August 6, 2007
Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
Chemistry World
November 4, 2011
Phillip Broadwith |
Chemists put finger on the trigger to attack cancer Hydrogen peroxide-triggered release mechanisms could help reduce the side effects of cancer drugs by keeping them safely locked up until they reach the oxidizing environment of cancer cells, say scientists in the US. |
Chemistry World
April 3, 2008
Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Chemistry World
July 1, 2013
James Urquhart |
Antibiotic research hits a sweet spot UK researchers have found a way to weaken the molecular armour of Escherichia coli to allow the host's immune system to attack and kill the pathogen. |
Chemistry World
August 25, 2010
Phillip Broadwith |
Antibiotic nanoparticles go for gold Chemists in the UK and India have developed a simple, one step synthesis of gold nanoparticles incorporating an antibiotic, without using any other chemicals. |
American Family Physician
September 15, 2006 |
When Antibiotics Can Help A consumer's guide: What are antibiotics?... How do antibiotics work?... What is antibiotic resistance?... How can I prevent antibiotic resistance?... |
Chemistry World
March 6, 2013
Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World
September 24, 2015
Harriet Brewerton |
Antibiotics pit against bacterial biofilms Scientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics. |
Chemistry World
April 2012
Anthony King |
Making Light Work Could light prove to be the ultimate weapon in the battle against deadly superbugs? |
Chemistry World
August 19, 2009
Phillip Broadwith |
Antioxidants could promote cancer Some tumor cells can actually use antioxidants to protect themselves from natural cellular defense mechanisms, enabling them to survive and proliferate. |
Chemistry World
April 27, 2011
Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
Chemistry World
January 30, 2015
Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Chemistry World
May 6, 2014
Andy Extance |
WHO raises alarm on deadly bacteria The World Health Organization has warned antibiotic resistant bacteria could bring a nightmarish future, where seemingly trivial scrapes turn lethal, and currently routine operations become too risky to contemplate. |
Chemistry World
April 4, 2007
John Bonner |
Antibiotic Combinations Tackle Resistance Using combinations of certain antimicrobial compounds can favor the growth of non-resistant strains of bacteria at the expense of resistant ones. The surprising finding may provide a general strategy to help eradicate strains of bacteria that are resistant to antibiotic therapy. |
American Family Physician
January 15, 2004 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics work against all infections?... What is "antibiotic resistance"?... Why should I worry about antibiotic resistance?... How do I know when I need antibiotics?... How should I take the antibiotics that my doctor prescribes?... etc. |
Chemistry World
March 13, 2013
Ned Stafford |
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. |
Chemistry World
April 4, 2011
Carol Stanier |
Mighty micelles that make themselves Scientists in the US and Singapore have made self assembling micelles of cationic polymers that kill bacteria but are biodegradable - raising further hope of a nanotechnology solution to the problem of antibiotic resistance. |
Chemistry World
October 31, 2012
Ian Le Guillou |
A cell for a cell If you ever need to isolate a single bacterial cell, why not build it a prison cell? This is the approach that colleagues from Sandia National Laboratories, US, have taken. Using multi-photon lithography, they can construct four walls and a roof around a single cell in just over a minute. |
American Family Physician
March 15, 2001 |
Avoiding Resistance to Antibiotics-- When Do I Need an Antibiotic? When bacteria are exposed to the same antibiotics, after a while the antibiotic can't fight the germs anymore... |
Chemistry World
October 8, 2013
David Bradley |
3D printing bacteria Jason Shear and colleagues at the University of Texas, US, have developed a 3D printing technique that lets them 'construct' defined bacterial communities so that short-range chemical communications and physical interactions between bacteria can be investigated more systematically than ever before. |
Chemistry World
July 8, 2014
Anthony King |
Call for new models to pay for antibiotics Governments will need to think seriously about changing the way they pay for the drugs. That's the conclusion of a report from the UK House of Commons science and technology committee. |
Chemistry World
March 26, 2014
Katia Moskvitch |
Nanoparticle sensors detect drug damage in the liver Stanford University researchers have created nanoparticle-based sensors that can image metabolites in animal livers, which they say could help eliminate toxic drug candidates before they are given to humans. |
Fast Company
May 2009
Elizabeth Svoboda |
Biotechs Wage War on Superbugs With antibiotic resistance on the rise, three biotechs are developing new ways to wage war on superbugs. |
Chemistry World
May 7, 2014
Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World
February 6, 2013
Harriet Brewerton |
Diagnosing bacterial growth Antibiotics are used regularly for treating bacterial infections, but there is currently no quick and simple test to determine the most effective type or dose of antibiotic for a specific patient infection. |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
American Family Physician
October 1, 2004 |
Antibiotics: When They Can and Can't Help An overview on how antibiotic therapy comes into play in the treatment of the flu and colds. |
Chemistry World
December 11, 2014 |
Merck to buy antibiotics specialist Cubist Hours after the deal was announced, a US District Court invalidated several key patents for Cubist's top seller, Cubicin (daptomycin). |
Managed Care
June 2004
Jack McCain |
Health Plans Respond as Microbes Develop Resistance Techniques Managed care is having some success discouraging practices that promote the development of "superbugs." |
HHMI Bulletin
Spring 2013
Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
American Family Physician
October 1, 2006 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics always work?... What is bacterial resistance?... What can I do to help myself?... etc. |
Chemistry World
December 7, 2011
Andrea McGhee |
Artificial enzyme outperforms nature Scientists in China and the US have fabricated an artificial enzyme that may provide new hope for the treatment of Lou Gehrig's disease. |
Chemistry World
July 26, 2010
Phillip Broadwith |
Predicting nanoparticle toxicity Judging nanoparticle toxicity could be made easier by a new theoretical model that predicts which materials will make nanoparticles that could damage living cells. The model can predict the available electronic energy levels in the nanoparticle structure |
Chemistry World
July 28, 2009
Michael Gross |
DNA to direct and switch off chemo Researchers in the US have developed a new approach to cancer chemotherapy using short DNA strands to help target delivery of the drug directly to cancer cells, and 'call it off' should problems arise. |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
American Family Physician
December 15, 2000 |
Antibiotics: When They Can and Can't Help Antibiotics are strong medicines that can stop some infections and save lives. When they aren't used the right way, antibiotics can cause more harm than good. You can protect yourself and your family by knowing when you should use antibiotics and when you should avoid them... |
Nutrition Action Healthletter
May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
Chemistry World
July 15, 2010
Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Scientific American
June 2008
Melinda Wenner |
How Cells Make Use of Random Biochemical Reactions New studies reveal how cells exploit biochemical randomness. |
