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HHMI Bulletin May 2011 Sarah C.P. Williams |
The Pace of Evolution A close look at the human genome shows the slow and steady beat of adaptation. |
Bio-IT World February 11, 2005 Kevin Davies |
Bioinformatics on the Brain Adaptive selection: accelerated mutation rate produced humans' large brain. |
Scientific American June 2009 Melinda Wenner |
Genetic Copy Variations and Disease A new sense for how variable numbers of genes cause disease. |
Reason Aug/Sep 2000 Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
Bio-IT World June 17, 2004 Michael A. Goldman |
A Hip Approach to Gene Hunting IntegraGen defines the genetic blueprint of complex human diseases and delivers validated disease markers and therapeutic targets for a better diagnosis and a causal treatment of common diseases, based on its unique genomic analysis expertise. |
Bio-IT World February 10, 2003 Kevin Davies |
With a Click of the Mouse What do Eminem and Mus musculus have in common? About 30,000 genes, for a start. The author mulls over the second mammalian genome. |
Bio-IT World October 2005 Kevin Davies |
Monkey Business The impact of the chimpanzee genome is not confined to science. It offers an urgent reminder of the endangered status of many primate species. |
HHMI Bulletin Nov 2010 Jennifer Michalowski |
Mimicking a Fruit Fly's Natural Environment Yields Genetics Discovery The tiniest hairs on fruit fly larvae have complex genetic controls that David Stern almost missed -- until he took the fruit flies out of their cozy incubators. |
Fast Company November 2009 David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
HHMI Bulletin May 2012 Sarah C. P. Williams |
Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases. |
HHMI Bulletin Nov 2010 Sarah C.P. Williams |
Scientists Track Down Genetic Mutations In Record Time Scanning the human genome for a single disease-causing mutation is like taking a copy of War and Peace in a foreign language and searching for one misspelled word |
Bio-IT World January 21, 2005 Kevin Davies |
Simulated Shades of Jurassic Park? Bioinformatics researchers have re-created part of the genome sequence of an ancestral mammal that lived 70 million to 80 million years ago. |
Chemistry World June 6, 2007 Simon Hadlington |
Large-Scale Gene Scanning for Common Diseases A multi-center genome scanning project that has analyzed half a million genetic markers in thousands of healthy people and people with a range of common diseases has revealed previously unknown genetic variants of the diseases. |
Bio-IT World Dec 2006/Jan 2007 Kevin Davies |
The One Percent Difference New research reveals a shocking new layer of human genome variation with profound implications for the future of genomic analysis and personalized medicine. |
Bio-IT World March 8, 2005 Kevin Davies |
Evolution of New Genes Studied EMBL researchers use comparative genomic analysis to identify new primate-specific gene family. |
Wired August 2000 Jennifer Hillner |
Area 22 The inside story of the first fully sequenced chromosome. |
Scientific American December 19, 2005 |
Lean Gene Machine An ocean bacterium has the most streamlined genome: P. ubique apparently has traded potential for economy in a big way, making its genome the equivalent of a fuel-stingy Volkswagen Beetle, whereas human DNA is more akin to a gas-guzzling Hummer pulling an RV trailer plus a boat. |
Popular Mechanics November 12, 2009 Bijal P. Trivedi |
5 Animal Genomes That May Hold Cures to Human Diseases Having the genomic information will guide pharmaceutical assessments and new experimental gene therapies, many of which are being done in animals. |
Bio-IT World October 2005 Dennis A. Gilbert |
The DNA Sequencing Race: From Sprint to Marathon To create faster, cheaper, and better solutions for DNA analysis, we must remain committed to improving both current and new sequencing technologies. Research that just a short while ago might have been considered too complex, too expensive, or just inconceivable is now well within our grasp. |
BusinessWeek May 9, 2005 |
A Genome Pioneer Looks Forward Dr. Francis Collins discusses the end of the Human Genome Project and says an "outpouring of discoveries" is coming soon. |
Wired November 17, 2007 Thomas Goetz |
23AndMe Will Decode Your DNA for $1,000. Welcome to the Age of Genomics A much-anticipated Silicon Valley startup called 23andMe offers a thorough tour of your genealogy, tracing your DNA back through the eons. |
Bio-IT World June 12, 2002 Kevin Davies |
Variations on a Theme Researchers at Genaissance Pharmaceuticals have outlined the path to creating a comprehensive map of human genomic variation that should ultimately reveal the genetic underpinnings of common diseases. |
BusinessWeek June 13, 2005 John Carey |
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. |
BusinessWeek May 9, 2005 John Carey |
Dr. Francis S. Collins: On The Trail Of Disease Genes Collins is leading the search for DNA variations that can result in illnesses. |
Salon.com June 27, 2000 Ralph Brave |
Building better humans The sci-fi possibilities of genetic tampering may soon become real. And there's no law against them. |
Bio-IT World August 15, 2005 Kevin Davies |
TGen's Discovery Pipeline in the Desert At the Translational Genomics Research Institute, researchers have developed an industrial-style informatics strategy and discovery infrastructure that has pinpointed some 25 disease genes in the past 24 months, many of which are pending identification. |
Chemistry World March 4, 2015 Thadchajini Retneswaran |
Computational chemists unpick adenine -- thymine bias A chemical model has been created to investigate the evolution of guanine -- cytosine coding regions and found that certain spontaneous mutations are more likely to arise at specific regions of DNA. |
Chemistry World May 22, 2014 Philip Ball |
Is junk DNA all garbage? It would be hard to find a recent scientific study that has excited more controversy than that of the international collaboration Encode. They suggested that up to 80% of our DNA was functional. |
Scientific American July 2009 Charles Q. Choi |
Being More Infantile May Have Led to Bigger Brains Genetic evidence suggests that juvenile traits helped separate chimps from us |
Salon.com May 1, 2000 Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Chemistry World September 14, 2011 David Bradley |
Brewing up Synthetic Yeast Yeast with synthetic genomes could be very useful for medicinal chemists and drug companies. |
Wired April 2006 Steve Olson |
Bringing Back the Brontosaurus Digging for fossils is for dinosaurs. Today's animal trackers are using genomics to reconstruct, and one day resurrect, the original hot-blooded beast. |
HHMI Bulletin May 2012 Sarah C. P. Williams |
Stephen Quake: Innovative Thinking on Genetic Tests His ideas have already led to a blood test to tell a pregnant woman whether her fetus has Down syndrome. Now, the HHMI investigator is pushing further, to track the success of heart transplants and diagnose autoimmune diseases and allergies. |
Bio-IT World January 21, 2005 Kevin Davies |
Allen Brain Institute Debuts 'Google for Gene Activity' The Allen Institute for Brain Science has released its first set of gene-expression data in the brain for nearly 2,000 mouse genes. The data will have important relevance for the study of brain function, disease, and the role of genes in governing human behavior. |
Bio-IT World September 9, 2002 Kevin Davies |
The Debate Over Race Relations Are self-identified labels of race useful in large-scale population genetic studies? A provocative commentary from a leading Stanford University geneticist has fuelled controversy. |
Managed Care August 2004 Thomas Morrow |
10,000 Cells on a Chip Signal Start of New Era of Diagnosis Diseases will soon be defined by biochemical pathways and genetic interactions. Biochips may identify patients likely to respond to therapeutic agents. All of this is a big deal for health plans. |
IEEE Spectrum March 2013 Eliza Strickland |
The Gene Machine and Me Ion Torrent's chip-based genome sequencer is cheap, fast, and poised to revolutionize medicine |
Salon.com February 13, 2001 Arthur Allen |
Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly... |
BusinessWeek October 23, 2008 |
The Story in Your Genes There's tremendous value in genetic data, but it depends on how deeply you look. |
BusinessWeek November 7, 2005 Catherine Arnst |
How Likely Are You To Get Sick? A new DNA database could gauge your risk for disease. |
Chemistry World March 27, 2014 James Urquhart |
Synthetic yeast chromosome is fully functional The first complete and functional synthetic yeast chromosome has been created by a team of scientists based in the US. |
Bio-IT World March 10, 2003 |
Discovery Zone It's high time molecular biology became quantitative, and other thoughts from Sir John Maddox. |
Salon.com June 27, 2000 Tabitha M. Powledge |
Book of life? Hosanna! The Human Genome Project has been completed. We will now cure diseases, weed out defective genes and create a new supergeneration in the near future. Not. |
Wired July 2006 Annalee Newitz |
Code of the Caveman A new DNA mapping technique may solve an ancient mystery: Do modern humans carry Neanderthal genes? |
Technology Research News June 4, 2003 Kimberly Patch |
Artificial beings evolve realistically Researchers from Michigan State University, Cal Tech, and the University of California at Los Angeles have found a way to use software to more closely mimic the way real organisms evolve, and have used the model to uncover a long-standing secret of natural selection. |
Chemistry World August 26, 2007 Michael Gross |
Grapevine Genome Reveals Wine's Flavour Secrets The genome of the grapevine, Vitis vinifera, has been decoded by scientists. The research reveals the genetic origins of certain aromas and health-promoting compounds in wine. |
HHMI Bulletin Nov 2011 Dave Mosher |
A New PACE for Laboratory Evolution Researchers have found a way to accelerate evolution of molecules by harnessing viruses. |
Wired July 21, 2008 Thomas Goetz |
How the Personal Genome Project Could Unlock the Mysteries of Life The project will turn information from 100,000 subjects into a huge database that can reveal the connections between our genes and our physical selves. Here's how. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. |