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HHMI Bulletin Nov 2010 Sarah C.P. Williams |
Scientists Track Down Genetic Mutations In Record Time Scanning the human genome for a single disease-causing mutation is like taking a copy of War and Peace in a foreign language and searching for one misspelled word |
HHMI Bulletin February 2011 |
Crucibles of Dynamism Puzzling pockets of redundancy account for about 5 percent of the human genome. Investigator Evan Eichler found a way to interpret what is happening in these areas of genetic repetition. |
Bio-IT World February 11, 2005 Kevin Davies |
Bioinformatics on the Brain Adaptive selection: accelerated mutation rate produced humans' large brain. |
Technology Research News June 4, 2003 Kimberly Patch |
Artificial beings evolve realistically Researchers from Michigan State University, Cal Tech, and the University of California at Los Angeles have found a way to use software to more closely mimic the way real organisms evolve, and have used the model to uncover a long-standing secret of natural selection. |
HHMI Bulletin May 2012 Sarah C. P. Williams |
Opening the Floodgates Researchers are using exome sequencing -- zeroing in on the genes that encode proteins -- to explore the biology of certain diseases. |
Bio-IT World March 8, 2005 Kevin Davies |
Evolution of New Genes Studied EMBL researchers use comparative genomic analysis to identify new primate-specific gene family. |
Bio-IT World October 2005 Kevin Davies |
Monkey Business The impact of the chimpanzee genome is not confined to science. It offers an urgent reminder of the endangered status of many primate species. |
Scientific American June 2009 Melinda Wenner |
Genetic Copy Variations and Disease A new sense for how variable numbers of genes cause disease. |
HHMI Bulletin Nov 2011 Dave Mosher |
A New PACE for Laboratory Evolution Researchers have found a way to accelerate evolution of molecules by harnessing viruses. |
Technology Research News May 21, 2003 Kimberly Patch |
Simulated evolution gets complex Researchers from Michigan State University have used software to prove Charles Darwin's postulation that small, seemingly inconsequential changes over thousands of generations can result in the evolution of complex functions. |
Bio-IT World June 2006 Graeme O'Neill |
Why Variety Is the Spice of Life In an effort to bring order to the field of single nucleotide polymorphism research data collection and management, pioneering mutation hunter Richard Cotton has organized The Human Variome Project Meeting in Melbourne, Australia. |
BusinessWeek June 13, 2005 John Carey |
The NIH's Roadmap for Research Charting the human genome was just the beginning. Now the focus is creating pathways that will lead to practical applications. |
Chemistry World October 12, 2006 Jessica Ebert |
Reducing the Number of Genes Needed for Life Two of the smallest bacterial genomes sequenced to date provide new clues to the minimum number of genes required to support cellular life. |
BusinessWeek May 9, 2005 John Carey |
Dr. Francis S. Collins: On The Trail Of Disease Genes Collins is leading the search for DNA variations that can result in illnesses. |
Wired August 2000 Jennifer Hillner |
Area 22 The inside story of the first fully sequenced chromosome. |
Scientific American December 19, 2005 |
Lean Gene Machine An ocean bacterium has the most streamlined genome: P. ubique apparently has traded potential for economy in a big way, making its genome the equivalent of a fuel-stingy Volkswagen Beetle, whereas human DNA is more akin to a gas-guzzling Hummer pulling an RV trailer plus a boat. |
Smithsonian February 2007 Eric Jaffe |
Meditate on It Could ancient campfire rituals have separated us from Neanderthals? |
Chemistry World September 14, 2011 David Bradley |
Brewing up Synthetic Yeast Yeast with synthetic genomes could be very useful for medicinal chemists and drug companies. |
HHMI Bulletin Winter 2013 Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning. |
Reason Aug/Sep 2000 Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
Salon.com May 1, 2000 Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Bio-IT World September 9, 2002 Kevin Davies |
The Debate Over Race Relations Are self-identified labels of race useful in large-scale population genetic studies? A provocative commentary from a leading Stanford University geneticist has fuelled controversy. |
Chemistry World August 26, 2007 Michael Gross |
Grapevine Genome Reveals Wine's Flavour Secrets The genome of the grapevine, Vitis vinifera, has been decoded by scientists. The research reveals the genetic origins of certain aromas and health-promoting compounds in wine. |
Scientific American July 2009 Charles Q. Choi |
Being More Infantile May Have Led to Bigger Brains Genetic evidence suggests that juvenile traits helped separate chimps from us |
Bio-IT World October 2005 Dennis A. Gilbert |
The DNA Sequencing Race: From Sprint to Marathon To create faster, cheaper, and better solutions for DNA analysis, we must remain committed to improving both current and new sequencing technologies. Research that just a short while ago might have been considered too complex, too expensive, or just inconceivable is now well within our grasp. |
BusinessWeek October 23, 2008 |
The Story in Your Genes There's tremendous value in genetic data, but it depends on how deeply you look. |
Technology Research News July 14, 2004 Kimberly Patch |
Probabilities ease genetic logic Genetic algorithms are turning out to be useful for optimizing designs and solving problems. Researchers have devised a compact genetic algorithm that speeds the process by allowing a representation of the population as a whole to be passed back and forth rather than more voluminous information about individuals. |
Popular Mechanics November 12, 2009 Bijal P. Trivedi |
5 Animal Genomes That May Hold Cures to Human Diseases Having the genomic information will guide pharmaceutical assessments and new experimental gene therapies, many of which are being done in animals. |
Salon.com December 19, 2000 Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
Bio-IT World June 17, 2004 Michael A. Goldman |
A Hip Approach to Gene Hunting IntegraGen defines the genetic blueprint of complex human diseases and delivers validated disease markers and therapeutic targets for a better diagnosis and a causal treatment of common diseases, based on its unique genomic analysis expertise. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
Salon.com June 27, 2000 Tabitha M. Powledge |
Book of life? Hosanna! The Human Genome Project has been completed. We will now cure diseases, weed out defective genes and create a new supergeneration in the near future. Not. |
Scientific American July 2008 Christine Soares |
Looking at Yesterday's Genes for Tomorrow's Cures Resurrected "jumping gene" could deliver DNA. |
Bio-IT World October 2006 Kevin Davies |
Cracking the Cancer Genome Regardless of which technologies win out, or which centers win the lucrative sequencing contracts, the Cancer Genome Atlas has a sublime medical and scientific importance, underscored by the latest findings from Hopkins. |
Bio-IT World February 18, 2004 |
The Quest for Complex Genes Genetic sleuths are homing in on genes for complex diseases with the help of new, and some not so new, tools and strategies. |
Chemistry World January 12, 2015 Emma Stoye |
Protein mutant libraries to probe diseases' genetic link quickly and cheaply Researchers in the US have developed a faster and less costly way to investigate the effects of genetic mutations on proteins, which should offer new insights into hereditary diseases. |
HHMI Bulletin Fall 2012 Trisha Gura |
Teaching Genomics, Plainly Students at Franklin & Marshall College, searched databases of gene sequences, engineered bacteria to shuttle mutated genes into cells, and captured images of how those cells reacted to the alterations. |
Chemistry World June 6, 2007 Simon Hadlington |
Large-Scale Gene Scanning for Common Diseases A multi-center genome scanning project that has analyzed half a million genetic markers in thousands of healthy people and people with a range of common diseases has revealed previously unknown genetic variants of the diseases. |
Salon.com June 27, 2000 Ralph Brave |
Building better humans The sci-fi possibilities of genetic tampering may soon become real. And there's no law against them. |
Chemistry World October 1, 2008 Hayley Birch |
Chemical Knockout for Chlamydia US scientists have used chemical inhibitors to block proteins that Chlamydia produces as it invades cells. |
Bio-IT World April 15, 2003 Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Salon.com February 13, 2001 Arthur Allen |
Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly... |
HHMI Bulletin Feb 2012 Nicole Kresge |
Bones, Stones, and Genes Students and teachers joined five experts in what may have been the largest stone tool-making session in the history of human evolution. |
The Motley Fool December 10, 2004 Rich Duprey |
Scientists Play Chicken An international scientific consortium decodes the chicken genome. This information may be of use to companies such as Tyson, Pilgrim's Pride, Cal-Maine or even Buffalo Wild Wings. |
HHMI Bulletin Nov 2011 Renee Twombly |
A New Take on Retinoblastoma Basic research findings upend old thoughts on this childhood tumor. |
HHMI Bulletin Nov 2010 Jennifer Michalowski |
Mimicking a Fruit Fly's Natural Environment Yields Genetics Discovery The tiniest hairs on fruit fly larvae have complex genetic controls that David Stern almost missed -- until he took the fruit flies out of their cozy incubators. |
Geotimes August 2007 Erin Wayman |
DNA Holds Clues to Extinction A new DNA study is showing that mammoths were in decline before humans hunted them en masse. |
Bio-IT World February 10, 2003 Kevin Davies |
With a Click of the Mouse What do Eminem and Mus musculus have in common? About 30,000 genes, for a start. The author mulls over the second mammalian genome. |
The Motley Fool January 14, 2010 Brian Orelli |
$1,000 Genomes, Here We Come Illumina jumps on news of its $10,000 genome. |
Reason December 2007 Ronald Bailey |
X Crops Anti-biotech activists continue to fret about the possible dangers of such foods. Yet they ignore the less controlled reshuffling of genes that occurs through the more widespread and longstanding practice of mutation breeding. |