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Chemistry World
June 24, 2010
Phillip Broadwith
Aryl rings get a fluorine fix A mild and effective method for coupling trifluoromethyl groups on to aryl rings has been developed by US chemists. mark for My Articles similar articles
Chemistry World
November 3, 2011
David Bradley
Faster Synthesis of Fluorine Radioisotope Imaging Agents A palladium-containing fluorination reagent can be used to quickly synthesise aromatic molecules labelled with fluorine-18, a positron emitter used in molecular imaging. mark for My Articles similar articles
Chemistry World
August 24, 2010
Lewis Brindley
A better way to add radioactive fluorine Making compounds that contain the useful radioisotope fluorine-18 ( 18F) could be much easier in future, say researchers in the UK and Finland. mark for My Articles similar articles
Chemistry World
January 23, 2012
James Urquhart
Simple One Stop Shop for Difluoromethylation A new process developed by researchers opens the way for adding difluoromethyl (CF 2H) groups to drugs and agrochemicals in order to enhance their properties. mark for My Articles similar articles
Chemistry World
August 15, 2011
Simon Hadlington
Trifluoromethylation Made Easy US researchers have discovered a simple, low-cost way to add fluorine atoms to heteroaromatic rings. mark for My Articles similar articles
Chemistry World
March 19, 2009
Manisha Lalloo
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings mark for My Articles similar articles
Chemistry World
August 29, 2008
Fred Campbell
Breaking the bonds of global warming US scientists have managed to prise apart the highly unreactive carbon-fluorine bond at room temperature, potentially paving the way to the efficient disposal of hydrofluorocarbons -- highly stable and long-lived greenhouse gases. mark for My Articles similar articles
Chemistry World
September 18, 2015
Tim Wogan
Shining a light on amine synthesis A new method for site selective amination of aromatic organic compounds has been developed by researchers in the US. mark for My Articles similar articles
Chemistry World
January 2011
Column: In the pipeline Some medicinal chemists can't get enough fluorines in their molecules. The love-hate relationship is explained. mark for My Articles similar articles
Chemistry World
July 3, 2015
Andy Extance
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
January 11, 2013
Marie Cote
Following her passion Veronique Gouverneur is professor of chemistry at the University of Oxford, UK. She investigates fluorine chemistry and is working on developing novel synthetic methodologies for the preparation of fluorinated targets. mark for My Articles similar articles
Chemistry World
September 13, 2012
Ian Le guillou
Fluorination via porphyrin A manganese porphyrin has been used to selectively fluorinate sp 3 carbon -- hydrogen bonds using silver fluoride as a source of fluorine. mark for My Articles similar articles
Chemistry World
April 28, 2011
Simon Hadlington
New method for aromatic coupling Chemists in Switzerland have developed a way to couple aromatic rings through the Friedel-Crafts mechanism - something many people would have believed impossible. mark for My Articles similar articles
Chemistry World
May 31, 2009
Nina Notman
The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used. mark for My Articles similar articles
Chemistry World
June 23, 2011
Simon Hadlington
Breaking the carbon-fluorine bond US chemists have discovered a new way to break the bond between carbon and fluorine atoms - the strongest carbon bond there is. mark for My Articles similar articles
Chemistry World
August 2008
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? mark for My Articles similar articles
Chemistry World
June 14, 2006
Simon Hadlington
Natural Metabolism of Fluorine Scientists have isolated a cluster of bacterial genes responsible for the biochemical processing of fluorine. The research follows the discovery of a unique enzyme that incorporates inorganic fluoride into organic metabolites. mark for My Articles similar articles
Chemistry World
June 15, 2009
Matt Wilkinson
Concert arranges billion dollar GSK deal US-based Concert Pharmaceuticals has inked its first commercialization deal granting GlaxoSmithKline access to six deuterium-modified drugs mark for My Articles similar articles
Chemistry World
June 5, 2006
Simon Hadlington
The Attraction of Gold for Gold Researchers are unravelling some of the fundamental chemistry surrounding a key but poorly understood aspect of the coordination chemistry of gold -- the weak `aurophilic' interactions between adjacent atoms of Au(I) in organic complexes. mark for My Articles similar articles
Chemistry World
May 29, 2015
Derek Lowe
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. mark for My Articles similar articles
Chemistry World
January 20, 2010
James Urquhart
Disilicate synthesis success A compound containing a stable silicon-silicon bond between two negatively charged pentacoordinated silicon atoms - silicates - has been synthesized and isolated for the first time by Japanese researchers. mark for My Articles similar articles
Chemistry World
March 2012
Column: In the pipeline Drug discovery requires experimentation, says Derek Lowe. But chemists can be reluctant to stray from the elements they know and love mark for My Articles similar articles
Chemistry World
December 19, 2010
Simon Hadlington
Novel route to key aromatics US chemists have found a new way to create aromatic compounds from straight chains of hydrocarbons by using an iridium-based catalyst. mark for My Articles similar articles
Chemistry World
September 12, 2013
Andy Extance
Sulfur difluoride dimer exposes bonding strangeness Calculations on unusual bonding in the sulfur difluoride dimer FSSF 3 have provided evidence to help explain why some compounds don't follow long-established chemical rules. mark for My Articles similar articles
Chemistry World
September 28, 2015
Karl Collins
A witches' brew for trifluoromethylation Trifluoromethylating phenols is one example of a reaction that would be incredibly useful when attempting to tune the chemical and biological properties of molecules for pharmaceutical and agrochemical research. mark for My Articles similar articles
Chemistry World
December 15, 2010
Hayley Birch
New technique probes electron properties of individual atoms A new, low voltage electron microscopy technique allows scientists to discriminate not just between atoms of different elements but between atoms of the same element in different electronic states. mark for My Articles similar articles
Chemistry World
November 18, 2014
Katrina Kramer
Molecules: the elements and the architecture of everything Molecules is a serious attempt to explain the world of chemical compounds to the reader without assuming previous science knowledge. mark for My Articles similar articles
Chemistry World
April 15, 2010
Simon Hadlington
Lead joins the aromatic ring club Scientists in Japan have successfully incorporated an atom of lead into an aromatic molecule - the heaviest metal so far to be 'aromatised'. mark for My Articles similar articles
Chemistry World
March 3, 2010
Jon Cartwright
Hydrocarbon turns superconductor Researchers in Japan have created the first superconducting material based on a molecule of carbon and hydrogen atoms. mark for My Articles similar articles
Chemistry World
January 13, 2011
Sarah Corcoran
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. mark for My Articles similar articles
Chemistry World
April 4, 2013
Phillip Broadwith
A solution to fluoronium riddle The first evidence for hypervalent fluorine cations, or fluoronium ions, in solution has been found by US chemists. mark for My Articles similar articles
Chemistry World
April 25, 2014
Derek Lowe
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. mark for My Articles similar articles
Chemistry World
August 2009
Derek Lowe
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder mark for My Articles similar articles
Chemistry World
May 28, 2015
Matthew Gunther
Purely inorganic aromatic ion synthesized Scientists in the US have successfully synthesized an aromatic ion made from only nitrogen and phosphorus. The anion is a rare example of a stable aromatic species containing no carbon atoms. mark for My Articles similar articles
Chemistry World
September 25, 2015
Derek Lowe
Spice up your compounds You and your team are optimizing a lead compound, as medicinal chemists are wont to do -- varying its structure to improve its potency, selectivity and other properties. mark for My Articles similar articles
Chemistry World
January 25, 2013
Derek Lowe
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? mark for My Articles similar articles
Chemistry World
July 16, 2009
Simon Hadlington
Strange vibrations Researchers in Taiwan have shown that in a relatively simple molecular system the induced vibrations can inhibit the breaking of the bond and slow the reaction down. mark for My Articles similar articles
Chemistry World
March 10, 2011
Kate McAlpine
Aerosol data from BP spill Analysis of atmospheric data suggests that emissions of intermediate volatile organic compounds and semi-volatile organic compounds were low compared with those of volatile organic compounds. mark for My Articles similar articles
Chemistry World
October 9, 2014
Katrina Kramer
Largest Mobius molecule synthesized Researchers from Korea and Japan have put a new twist on aromaticity, synthesizing the largest Mobius aromatic molecule to date. mark for My Articles similar articles
Technology Research News
May 4, 2005
Noisy Snapshots Show Quantum Weirdness Researchers have devised a relatively simple way to detect a pair of entangled, or linked atoms. The detection ability advances quantum computer and quantum communications research. mark for My Articles similar articles
Chemistry World
July 11, 2012
Neil Withers
Fluorine Finally Found in Nature Traces of elemental fluorine, F 2, have been found in calcium fluoride minerals by German chemists, who suggest that it's produced by uranium also found in the rock. mark for My Articles similar articles
Technology Research News
August 11, 2004
Single gold atoms altered The gold atom, positioned on an ultrathin film of sodium chloride, remained stable during the operation, despite the change in charge. mark for My Articles similar articles