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American Family Physician July 15, 2006 Mehta et al.	Opportunities to Improve Outcomes in Sickle Cell Disease Family physicians play a crucial role in instituting evidence-based preventive sickle cell care strategies, initiating timely treatment of acute illness, recognizing life-threatening episodes, and providing a medical home for multidisciplinary management.
American Family Physician September 1, 2000	Sickle Cell Disease in Childhood: Part I. Laboratory Diagnosis, Pathophysiology and Health Maintenance Family physicians and parents who have been educated about sickle cell disease can detect acute, life-threatening complications such as splenic sequestration crisis and acute chest syndrome at their onset, thereby allowing treatment to be instituted without delay...
Pharmaceutical Executive April 10, 2014 Ben Comer	Sickle Cell Disease In Three Acts Is there a happy ending in store for sickle cell patients?
American Family Physician July 1, 2000 Abilio Munoz	Diagnosis and Management of Acute Pancreatitis Acute pancreatitis usually occurs as a result of alcohol abuse or bile duct obstruction. A careful review of the patient's history and appropriate laboratory studies can help the physician identify the etiology of the condition and guide management.
American Family Physician November 15, 2000 John R. Brill & Dennis J. Baumgardner	Normocytic Anemia ...Normocytic anemia is the most frequently encountered type of anemia. Anemia of chronic disease, the most common normocytic anemia, is found in 6 percent of adult patients hospitalized by family physicians....
American Family Physician June 15, 2001 Peter J. Carek	Diagnosis and Management of Osteomyelitis Acute osteomyelitis is the clinical term for a new infection in bone. This infection occurs predominantly in children and is often seeded hematogenously...
American Family Physician January 15, 2001 Charles P. Mouton	Common Infections in Older Adults Despite advances in antibiotic therapy, infectious diseases continue to be a major cause of mortality in older adults. The diagnostic and therapeutic nuances of managing infections in older adults create special challenges for physicians...
American Family Physician July 15, 2006	When Your Child Has Sickle Cell Disease A patient's guide: What is sickle cell disease?... What problems can sickle cell disease cause?... What should I do if my child with sickle cell disease is in pain?... etc.
American Family Physician September 1, 2000	Sickle Cell Disease Sickle cell disease is a blood disease that children inherit from their parents. The disease causes the red blood cells to make abnormal hemoglobin. Hemoglobin is the part of blood that carries oxygen in the body...
American Family Physician October 15, 2001 Joseph J. Irwin	Anemia in Children Anemia in children is commonly encountered by the family physician. Multiple causes exist, but with a thorough history, a physical examination and limited laboratory evaluation a specific diagnosis can usually be established...
American Family Physician September 15, 2001 Richard Colgan & John H. Powers	Appropriate Antimicrobial Prescribing: Approaches that Limit Antibiotic Resistance Physicians should be familiar with the clinical situations in which they should provide antibiotics and those in which they may safely be withheld...
Nursing November 2011 Jeanne Held-Warmkessel	Taming Three High-Risk Chemotherapy Complications A review of three common chemotherapy-associated complications that can be serious enough to require hospitalization: febrile neutropenia, chemotherapy-related nephrotoxicity, and chemotherapy-related enterotoxicity.
American Family Physician November 1, 2000 Neil Abramson & Becky Melton	Leukocytosis: Basics of Clinical Assessment Leukocytosis, a common laboratory finding, is most often due to relatively benign conditions (infections or inflammatory processes). Much less common but more serious causes include primary bone marrow disorders...
American Family Physician February 1, 2001 Malcolm L. Brigden	Detection, Education and Management of the Asplenic or Hyposplenic Patient Management of patients with these conditions includes a combination of immunization, antibiotic prophylaxis and patient education...
Nursing January 2010 Brenner & Krenzer	Understanding acute pancreatitis Mr. White has classic signs and symptoms of acute pancreatitis. The onset is usually abrupt, often occurring after a large meal or excessive alcohol use.
American Family Physician March 1, 2005 Ramakrishnan & Scheid	Diagnosis and Management of Acute Pyelonephritis in Adults There are approximately 250,000 cases of acute pyelonephritis each year, resulting in more than 100,000 hospitalizations. The most common etiologic cause is infection with Escherichia coli.
American Family Physician November 1, 2006 Lyon & Clark	Diagnosis of Acute Abdominal Pain in Older Patients Acute abdominal pain is a common presenting complaint in older patients, but may be difficult to diagnose. Here are some common causes of abdominal pain in old patients and recommendations for treatment.
American Family Physician October 1, 2001 Karl E. Miller	Challenges in Pain Management at the End of Life Effective pain management in the terminally ill patient requires an understanding of pain control strategies. Ongoing assessment of pain is crucial and can be accomplished using various forms and scales...
American Family Physician February 1, 2007 Servey et al.	Clinical Presentations of Parvovirus B19 Infection Generally, erythema infectiosum is self-limited and does not require treatment. Patients with arthralgia may require nonsteroidal anti-inflammatory drug treatment.
American Family Physician November 1, 2005 Eddie Needham	Management of Acute Renal Failure Acute renal failure is an acute loss of kidney function that occurs over days to weeks and results in an inability to appropriately excrete nitrogenous wastes and creatinine. In spite of this rapid decline in kidney function, patients with acute renal failure often have few symptoms.
American Family Physician July 1, 2006 Junnila & Cartwright	Chronic Musculoskeletal Pain in Children: Part I. Initial Evaluation Musculoskeletal pain can be difficult for children to characterize. A logical and consistent approach to diagnosis is recommended, with judicious use of laboratory and radiologic testing.
American Family Physician September 15, 2006 Wong et al.	Guidelines for the Use of Antibiotics in Acute Upper Respiratory Tract Infections To help physicians with the appropriate use of antibiotics in children and adults with upper respiratory tract infection, a multidisciplinary team evaluated existing guidelines and summarized key practice points.
American Family Physician November 15, 2005 William E. Cayley	Diagnosing the Cause of Chest Pain Distinguishing between serious and benign causes of chest pain is imperative, and diagnostic and prognostic questions are important in making this determination.
American Family Physician August 2001 Saud Suleiman & David E. Johnston	The Abdominal Wall: An Overlooked Source of Pain When abdominal pain is chronic and unremitting, with minimal or no relationship to eating or bowel function but often a relationship to posture (i.e., lying, sitting, standing), the abdominal wall should be suspected as the source of pain...
American Family Physician July 1, 2005 Achar, Kundu & Norcross	Diagnosis of Acute Coronary Syndrome Differentiating acute coronary syndrome from noncardiac chest pain is the primary diagnostic challenge. The initial assessment requires a focused history (including risk factor analysis), a physical examination, an ECG and, frequently, serum cardiac marker determinations.
Nurse Practitioner September 2011 Cheryl L. Gainer	Celiac Disease: Helping Patients Live Gluten-Free A review of the screening, diagnosis, and treatment of celiac disease.
American Journal of Nursing May 2009 Patricia Connor-Ballard	Understanding and Managing Burn Pain: Part 2 Despite advances in treatment of burn injuries and their consequent pain, wound care is the main source of the pain associated with burn injury.
American Family Physician June 1, 2004 Dhaliwal, Cornett & Tierney	Hemolytic Anemia While hemolysis can be a lifelong asymptomatic condition, it most often presents as anemia when erythrocytosis cannot match the pace of red cell destruction. Hemolysis also can manifest as jaundice, cholelithiasis, or isolated reticulocytosis.
American Family Physician September 15, 2000 Anne D. Walling, M.D.	Family Practice International Notes from international family physicians' journals: Traumatic Coronary Artery Damage... Morton's Neuroma... Diagnosing Acute Dyspnea...
Nurse Practitioner November 2011 Tracy Brazziel et al.	Stopping the Wave of PAD Early detection and diagnosis of atherosclerotic disease is imperative. Here, learn the risk factors, screening and diagnosis for this disease.
Nursing September 2008 Susan Simmons Holcomb	Acute Abdomen: What a Pain! So many things - some life-threatening - can cause abdominal pain. Here's how to capture the clues quickly and accurately.
Nurse Practitioner May 2009 Yvonne D'Arcy	Is Low Back Pain Getting on Your Nerves? The pain and disability of low back pain are the most common reasons patients seek healthcare. Here are tools for diagnosis and treatment options.
American Family Physician June 1, 2003 Leung & Sigalet	Acute Abdominal Pain in Children Acute abdominal pain in children presents a diagnostic dilemma. Although many cases of acute abdominal pain are benign, some require rapid diagnosis and treatment to minimize morbidity. Numerous disorders can cause abdominal pain.
American Family Physician May 15, 2001 Allan Gottschalk & David S. Smith	New Concepts in Acute Pain Therapy: Preemptive Analgesia Preemptive analgesia, an evolving clinical concept, involves the introduction of an analgesic regimen before the onset of noxious stimuli, with the goal of preventing sensitization of the nervous system to subsequent stimuli that could amplify pain...
American Family Physician March 1, 2005 Carolyn J. Sachs	Oral Analgesics for Acute Nonspecific Pain Direct comparative studies of acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) have shown that NSAIDs are more effective than acetaminophen in some situations, but provide equivalent analgesia in others.
Nursing June 2008 Yvonne D'arcy	Nursing2008 Pain Management Survey Report See how your responses to this survey compare with those of nursing colleagues across the country and beyond.
Nursing October 2009 Yvonne D'Arcy	Overturning barriers to pain relief in older adults This article will describe how to lower the barriers to effective pain control in older patients and provide practical tips for helping them receive the full benefit from pharmacologic and nonpharmacologic therapies.
Pharmaceutical Executive October 1, 2012 Ben Comer	Stem Cells: A Promise Deferred? Ideology, politics, and a stilted political debate may be causing pharma to overlook the potential of emerging stem cell therapies in fostering a new generation of cures.
Nursing Management July 2010 Lois Welden	Transfusion confusion Over the past decade, literature has indicated that liberal use of blood transfusions results in poor clinical outcomes in the majority of critically ill patients.
American Journal of Nursing December 2010 Baldridge & Andrasek	Pain Assessment in People with Intellectual or Developmental Disabilities Nurses in all settings need to be knowledgeable about alternate pain assessment methods.
Chemistry World May 3, 2011 Michael Gross	New hope for malaria drugs as sickle cell protection unravelled Researchers have come up with a molecular mechanism that explains how it protects people from this deadly disease.
AskMen.com Stephane Leung	Heart Disease Prevention Myths With heart disease still the No. 1 killer across the U.S. and Canada, readers should be wary of some of the myths related to heart disease -- such as simply being male puts you at higher risk.
Chemistry World February 9, 2012 Harriet Brewerton	Pressurizing red blood cells for information Scientists in Canada have developed a method to study the changes in red blood cells caused by the most common malaria parasite Plasmodium falciparum.
HHMI Bulletin February 2012 Marc Wortman	Where Does It Hurt? Researchers are getting to the molecular details of pain's circuitry to answer the question with real specificity.
IEEE Spectrum August 2006 Schoenbach et al.	Zap Extreme voltage could be a surprisingly delicate tool in the fight against cancer. The list of effects that scientists have achieved using nanoseconds-long pulses is growing rapidly, though their actual use as a medical treatment is still years away.
American Journal of Nursing April 2010 Mary Curry Narayan	Culture's Effects on Pain Assessment and Management When patients belong to a culture or speak a language that's different from that of their health care provider, the provider faces additional challenges in successfully assessing and managing the patients' pain.
Managed Care May 2005	Microcircuit Devices Deliver Considerable Relief From Chronic Pain Recent advances in pain relief revolve around longer-lasting implantable devices. Can managed care afford not to have a pain management strategy?
AskMen.com Stephane Leung	Heart Health Q&A Questions on common concerns about heart disease.
American Family Physician February 1, 2007	Parvovirus B19: What You Should Know A patient guide: What is parvovirus B19?... What should I do if my child has fifth disease?... What should I do if I have a parvovirus B19 infection?...
American Journal of Nursing June 2008 Ellen Flaherty	How to Try This: Using Pain-Rating Scales with Older Adults Pain is often undertreated and underdiagnosed in older adults. Regular use of short, simple, reliable pain-rating scales provides nurses and physicians with measurable information to establish and modify a pain management plan.