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Chemistry World February 21, 2012 Phillip Broadwith |
Nanopore sequencing bags its first genome Oxford Nanopore has presented the first complete genome to be sequenced using a nanopore. |
Chemistry World November 29, 2010 James Mitchell Crow |
DNA readers ratchet closer Rapid, cheap DNA sequencing has just edged a step closer, thanks to a new technique to control the motion of single DNA strands as they pass through a protein nanopore 'reader'. |
IEEE Spectrum June 2009 Prachi Patel |
Advance in Nanopore Gene Sequencing Magnets help in the quest for the $1000 genome |
Chemistry World October 13, 2015 Simon Hadlington |
DNA movement through motor proteins measured Researchers have adapted a method for DNA sequencing to measure directly and with exquisite sensitivity the movement of a single molecule of DNA as it is drawn through specialized motor proteins. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
Chemistry World April 3, 2008 Lewis Brindley |
DNA Read in a Trice The prospect of treatments that are tailored to fit an individual's genetic makeup is a step closer thanks to technology unveiled by US scientists. |
Chemistry World April 25, 2006 Jon Evans |
DNA Sequencing Reaches the Space Age The smallest ever DNA sequencer, only 10cm in diameter, comprises a complex network of microscopic pumps, valves, heaters and electrophoresis channels, many of which were initially developed for use in a device to detect life on Mars. |
Chemistry World July 21, 2011 James Mitchell Crow |
Sequencing Chip Decodes DNA Proton by Proton Technology that can directly detect the chemical reaction as a single nucleotide adds to the end of a growing strand of DNA is about to slash the cost of genome sequencing, its inventors say. |
Chemistry World January 20, 2011 James Urquhart |
SNPs on display DNA origami and atomic force microscopy have been combined to reliably detect and image single nucleotide polymorphisms, the most common form of genetic variation in the human genome. |
Technology Research News June 15, 2005 Kimberly Patch |
DNA Machine Links Molecules Researchers have fashioned a nanomechanical device from DNA that can be programmed to align a series of molecules and fuse them together. The technique could potentially be used to put together designer polymers, encrypt information, and carry out computations. |
Chemistry World September 17, 2012 Ian Le Guillou |
Raising the curtain on single-stranded DNA Scientists have created microfluidic devices containing single-stranded DNA 'curtains' for the first time, allowing scientists to study its interactions with proteins in real time. |
Chemistry World October 25, 2011 Jon Evans |
Carbon nanotubes detect DNA 'flipping out' US chemists have developed a way to detect the chemical modification of a single strand of DNA, by hooking it up to a pair of carbon nanotubes. |
Technology Research News September 24, 2003 |
Glow shows individual DNA Researchers have made a type of artificial DNA of that glows when it combines with a specific sequence of natural DNA. In principle, the method could be used to develop DNA chips that directly sense individual DNA molecules. |
Chemistry World July 4, 2010 Hayley Birch |
DNA sticks at flick of switch A new technique that sticks individual DNA molecules to a gold surface works at the flick of an electrochemical switch. |
Chemistry World May 16, 2007 Tom Westgate |
DNA Photography It is a technology that is fast disappearing in the digital age. But black and white photography is more than an archaic art-form to a team of German chemists who have used it as the basis for a simple method of detecting labeled DNA molecules at attomole levels. |
Chemistry World September 23, 2009 Simon Hadlington |
Direct route to RNA sequences Scientists in the US appear to have cracked a major problem in molecular biology: how to sequence single molecules of RNA directly. |
Chemistry World October 17, 2011 Hayley Birch |
Quickly sorting cells using DNA A new magnetic cell sorting technique uses principles borrowed from DNA nanodevices. The approach could help scientists rapidly separate different types of cells from complex mixtures. |
Chemistry World October 7, 2011 Sarah Farley |
Detecting diseases with DNA sensors DNA sensors detect pathogenic and genetic diseases by binding to target DNA strands that are related to the disease and giving a signal that shows how much of the DNA is present. |
Chemistry World November 7, 2013 Simon Hadlington |
Rocket-propelled read-out for new DNA chip US researchers have invented a lab-on-a-chip that can measure how much of a specific strand of DNA is in a sample using a 'rocket-propelled' thread of ink that can be read by eye. |
Technology Research News February 25, 2004 |
Nanowires spot DNA mutation Nanowire sensors could eventually be built into labs-on-a-chip that could be used for medical diagnostics and pathogen detection in the field, and for drug discovery. |
Chemistry World January 24, 2013 Laura Howes |
Shall I compare thee to a strand of DNA? For billions of years DNA has been life's data storage medium. Now, scientists have used DNA to code and store their media and information, from all of Shakespeare's sonnets to an audio recording of Martin Luther King's 'I have a dream' speech. |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Technology Research News August 22, 2005 |
DNA Technologies The versatile DNA molecule has proven to be a powerful technological building block. Researchers have developed ways of combining DNA molecules that allow them to carry out computations in test tubes and create two-dimensional patterns and three-dimensional structures at the nanoscale. |
Science News April 8, 2000 Ivars Peterson |
Hiding in DNA ...This use of DNA molecules to hide secret messages won Viviana I. Risca of Paul D. Schreiber High School in Port Washington, N.Y., the top prize at this year's Intel Science Talent Search... |
Technology Research News April 23, 2003 Kimberly Patch |
DNA motor keeps cranking Researchers have been making DNA perform all sorts of shape-changing tricks in recent years, but the need to add pieces of DNA at every step has made it a bit of a stretch to call these molecules motors. A method that keeps the process humming changes things. |
Technology Research News March 24, 2004 |
DNA has nano building in hand Researchers from Ludwig Maximilians University in Germany have built a simple molecular machine from DNA that can bind to and release single molecules of a specific type of protein. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Chemistry World September 12, 2010 Simon Hadlington |
Isotope effect seen on single molecule The isotope effect - where the rate of a reaction is altered depending on the presence of a given isotopic atom in the reactant - is a key tool for elucidating reaction mechanisms |
Chemistry World February 3, 2010 Lewis Brindley |
DNA origami goes large US researchers have found a way to scale up DNA origami into larger structures by using 'tiles' instead of 'staples' to pin them in place. |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Science News September 21, 2002 Ivars Peterson |
DNA's Error-Detecting Code Chemist Donall A. Mac Donaill of Trinity College in Dublin, Ireland, has now shown that patterns inherent in the chemical makeup of DNA correspond to a digital error-detecting code. |
Technology Research News December 29, 2004 |
DNA Makes and Breaks Particle Clumps Nanotechnology is all about manipulating materials on the molecular scale. Many teams of researchers are using artificial strands of DNA to do so. |
Chemistry World June 25, 2012 Simon Hadlington |
Bloody Solution to Electrochemical DNA Sensors US researchers have discovered a way to significantly improve the sensitivity of DNA-based electrochemical sensors by incorporating an inexpensive, robust and stable protein into the system - haemoglobin. |
Chemistry World May 6, 2009 Phillip Broadwith |
Nano-boxes from DNA origami Danish researchers have made a nano-sized box out of DNA that can be locked or opened in response to 'keys' made from short strands of DNA. |
HHMI Bulletin Feb 2011 |
DNA Curtains How proteins behave in such a crash test gives scientists data about their structural integrity, how they attach to DNA, and how they behave in a cell. |
Bio-IT World September 2005 Kevin Davies |
Fantastic 454: DNA Sequencing Pyrotechnics In an exciting advance for DNA sequencing technology, a research team at 454 Life Sciences Corp. has essentially sequenced and assembled a bacterial genome sequence based on a mere 4-hour run on the company's proprietary instrument. |
Chemistry World January 11, 2008 John Bonner |
DNA Nanoparticles Detect Gene Expression US scientists have made nanoparticles from DNA that they say could be used to identify the genes being expressed in a single cell. |
HHMI Bulletin February 2012 Sarah C. P. Williams |
Force Factor In the context of cells, forces are required to move molecules. Quantifying these forces gives scientists a way to compare and contrast different molecular motors. |
The Motley Fool August 12, 2009 Brian Orelli |
The Next Big Thing Is Not Right in Front of You Perhaps the fastest evolving technology right now is found in DNA sequencing. |
Chemistry World January 30, 2011 Mike Brown |
Electrons charge down DNA molecular wire US researchers have shown for the first time that a 34nm long DNA strand can be used as a molecular wire to conduct electricity. |
Technology Research News August 27, 2003 |
Detector senses single DNA Researchers from the University of California at Los Angeles have tapped differences in the folding characteristics of single-stranded and double-stranded DNA to make a sensor capable of detecting a single DNA molecule. |
Chemistry World May 7, 2014 Emma Stoye |
Bacterium survives unnatural DNA transplant The first organism that can grow and replicate with an unnatural base pair in its DNA -- giving the cell six nucleotides instead of the usual four -- has been created by scientists in the US. |
Chemistry World November 21, 2013 Phillip Broadwith |
Rapid DNA sequencing cleared for the clinic The approval covers Illumina's MiSeqDx instrument, together with two diagnostic assay kits for cystic fibrosis that run on it, and a kit that allows clinical labs to develop their own diagnostic tests. |
Chemistry World May 29, 2014 Hepeng Jia |
Chinese-made DNA sequencer aims to challenge foreign dominance With an independently developed next-generation DNA sequencer, Chinese scientists are aiming to challenge the dominance of international players in the world's fastest growing genome sequencing market. |
IEEE Spectrum August 2012 Emily Waltz |
Reading and Writing a Book With DNA Researchers are storing digital information in the form of DNA, but is it practical? Which will get us control of massively large data: electronic or molecular memory? |
Chemistry World October 8, 2009 Lewis Brindley |
IBM Enters Race for $1000 Genome Computer giant IBM is bringing its electronics expertise to biotechnology, and entering the race to map the human genome for less than $1000. |
Chemistry World February 27, 2006 Michael Gross |
A DNA Switch for RNA Folding Researchers have equipped a large RNA domain with a DNA switch, which they say can fold or unfold the RNA molecule at will. |
Technology Research News November 3, 2004 Smalley & Patch |
DNA Machines Take a Walk Researchers working to form nanoscale machines and materials are increasingly tapping into nature's building blocks. |
Chemistry World December 20, 2010 Jennifer Newton |
Frozen assets in biobanks Scientists from Sweden have devised a technique that extracts both DNA and RNA from frozen tissue in a bid to improve large-scale extractions from samples stored in biobanks, which could aid cancer research. |
Chemistry World September 8, 2014 Emma Stoye |
CPU heat powers PCR disease detection Scientists in the US have devised a new way of carrying out blood tests -- based on a modified computer and camera phone -- that could lower the costs of disease screening in developing countries. |