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Chemistry World
November 27, 2013
Derek Lowe
Rolling boulders uphill A lot of preclinical projects don't even get off the ground, and many that do still never deliver anything to the development groups. mark for My Articles similar articles
Chemistry World
January 2008
Derek Lowe
Column: In the Pipeline It's been a rough year, but the future looks bright for pharma. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
May 20, 2015
Katrina Kramer
Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs. mark for My Articles similar articles
Chemistry World
June 2010
Column: In the pipeline Derek Lowe looks into his crystal ball to see what the future of medicinal chemistry might be mark for My Articles similar articles
Chemistry World
September 2007
Derek Lowe
Column: In the Pipeline Will Phase Zero trials actually help drug development? mark for My Articles similar articles
Chemistry World
April 2011
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good. mark for My Articles similar articles
Chemistry World
May 2007
Derek Lowe
In the Pipeline After months of bleak news about faltering pipelines and redundancies, it's time to find reasons to be cheerful about the drug industry. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Chemistry World
December 2008
Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project. mark for My Articles similar articles
The Motley Fool
May 5, 2004
Brian Gorman
Albany Molecular Gets Out-Outsourced Albany Molecular Research, provider of chemistry services to biotech and pharmaceutical clients, is suffering from the loss of business to low-cost competitors overseas. mark for My Articles similar articles
Chemistry World
June 1, 2012
Derek Lowe
Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that. mark for My Articles similar articles
Chemistry World
December 17, 2012
Patrick Walter
RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists. mark for My Articles similar articles
Pharmaceutical Executive
March 1, 2007
Thought Leader: Joseph Brindisi, Kyowa Pharmaceuticals For discovery shops like Kyowa Pharmaceutical, which rely on optimizing the value of compounds in development, managing the pipeline and patent life is a major concern. mark for My Articles similar articles
Chemistry World
October 2010
Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery mark for My Articles similar articles
Chemistry World
April 2009
Derek Lowe
Column: In the pipeline The author considers the problems of addressing drug development out of sequence mark for My Articles similar articles
Chemistry World
September 2009
Column: In the pipeline What's the most difficult therapeutic area for drug discovery? They're certainly not all created equal - or if they were, they have definitely diverged since then. The question can be narrowed down quite a bit. mark for My Articles similar articles
Chemistry World
August 15, 2013
Lorenzo Caggiano
An introduction to medicinal chemistry (5th edition) An introduction to medicinal chemistry, by Graham Patrick, is exactly that and more. It is an essential text aimed at undergraduates and postgraduates studying aspects of medicinal chemistry. mark for My Articles similar articles
Food Processing
March 2009
Diane Toops
Kraft Foods Global Thinks Outside the Box with Bioactive Ingredients Kraft hires a pharmaceutical company to help it develop functional foods. mark for My Articles similar articles
Chemistry World
March 2012
Column: In the pipeline Drug discovery requires experimentation, says Derek Lowe. But chemists can be reluctant to stray from the elements they know and love mark for My Articles similar articles
Chemistry World
November 2006
Yfke Hager
Careers: Heartfelt Chemistry After working in New Zealand, medicinal chemistry tempted Ashley Jarvis back to the UK. He now works in his dream field. mark for My Articles similar articles
Reactive Reports
Issue 45
Star Picks Chemistry Web sites: Chemists Celebrate Earth Day: Resources... Doing Chemistry... Chemistry Question... mark for My Articles similar articles
Chemistry World
June 2007
Student Book Reviews Chemistry for CSI Fans... At the Heart of Molecular Biology... A Broad Vista of Chemistry...Rings Are Not Just for Carbons... etc. mark for My Articles similar articles
ONLINE
Sep/Oct 2007
Svetla Baykoucheva
A New Era in Chemical Information: PubChem, DiscoveryGate, and Chemistry Central How the emergence of PubChem, DiscoveryGate and Chemistry Central are changing the field of chemical information. mark for My Articles similar articles
The Motley Fool
July 6, 2010
Luke Timmerman
Rising From the Ashes of Pfizer: The Michigan Contract Research Organization Cluster Many of the people who honed their skills inside Pfizer and other big companies have found new entrepreneurial outlets to keep doing what they do best at a growing array of contract research organizations. mark for My Articles similar articles
Chemistry World
September 25, 2015
Derek Lowe
Spice up your compounds You and your team are optimizing a lead compound, as medicinal chemists are wont to do -- varying its structure to improve its potency, selectivity and other properties. mark for My Articles similar articles
The Motley Fool
September 28, 2006
Brian Lawler
Myriad Moves Forward The biotech's new cancer candidate passes phase 1 trials. Investors should take note, and make room for Myriad on their radar screens. mark for My Articles similar articles
Chemistry World
March 2012
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug mark for My Articles similar articles
Chemistry World
July 22, 2015
Judy Hayler
The handbook of medicinal chemistry: principles and practice The handbook of medicinal chemistry: principles and practice guides the reader through the R&D process from target validation to late stage clinical trials, via a series of chapters written by individuals in industry and academia. mark for My Articles similar articles
Pharmaceutical Executive
February 1, 2006
Ron Feemster
Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets. mark for My Articles similar articles
Investment Advisor
December 2005
Greg B. Scott
Buying The Future Prudent investing in biotechnology can offer great returns for clients. It's also the wave of the future. Armed with a basic understanding of the dynamics of the industry and the valuation inflection points, intelligent investors can make significant returns. mark for My Articles similar articles
Chemistry World
January 2012
Column: In the pipeline Derek Lowe discusses how companies are increasingly trying to do more with the compounds they already know a lot about mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Chemistry World
October 2008
Derek Lowe
Column: In the pipeline The author seeks a cure for 'compound bloat' mark for My Articles similar articles
Bio-IT World
September 2006
Kevin Davies
Pfizer's Global Survey of Pharmacological Space The pharma blends knowledge, computational chemistry and research informatics to build a unified database. Gathering all the data in one place offered greater control for indexing and data retrieval and management, enabling Pfizer scientists to perform global mapping. mark for My Articles similar articles
Fast Company
December 2009
Erica Westly
The Price of Winning FDA Approval Approval for a new drug or medical treatment requires extensive -- and expensive -- human trials for safety and effectiveness. mark for My Articles similar articles
Chemistry World
March 16, 2007
Testing Times for 'Mega-Pharma' A stern warning and gloomy forecast were delivered to the pharmaceutical industry at the Drug Discovery and Technology Summit in London. mark for My Articles similar articles
Chemistry World
December 2011
Bibiana Campos Seijo
Editorial: The End of a Good Start Chemistry can and should be celebrated every day. mark for My Articles similar articles
Chemistry World
June 2011
Column: In the pipeline Chemists are human. Humans are hierarchical. Therefore...well, therefore, you'll find a number of different roles and levels for scientists in a drug company's labs. Here's a rough ordering, from least experienced to most. mark for My Articles similar articles
Chemistry World
October 15, 2013
Dinsa Sachan
Supreme court ruling brings clinical trials to a halt in India The fate of 162 global clinical trials hangs in the balance, as the top Indian court has asked the government to provide more details on their approval process before they can proceed. mark for My Articles similar articles
The Motley Fool
January 16, 2008
Brian Lawler
Talking With a Development-Stage Pharma An interview with Dr. Leslie Browne, CEO of development-stage drugmaker Pharmacopeia. mark for My Articles similar articles
Chemistry World
December 2007
Richard Van Noorden
Surfing Web2O The rapid evolution of the world wide web is creating fresh opportunities - and challenges - for chemistry. mark for My Articles similar articles
Chemistry World
August 2009
Derek Lowe
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder mark for My Articles similar articles
Chemistry World
August 7, 2014
Christopher Exley
Bioinorganic chemistry This type of text was not available in the early days of bioinorganic chemistry and may now serve to fast track our understanding of the topic. mark for My Articles similar articles
Chemistry World
September 2008
Derek Lowe
Column: In the pipeline The author remembers leaving the ivory towers of academe to trade 'unusual and beautiful' for 'useful' mark for My Articles similar articles
Chemistry World
August 23, 2012
Simon Campbell
Protecting patients at all costs A new funding model is urgently required to deliver innovative medicines that meet the medical needs of the 21st century and contribute to economic growth. mark for My Articles similar articles
Pharmaceutical Executive
December 1, 2010
Walter Armstrong
Alzheimer's: A Disease at a Crossroads The need for new drugs intensifies as more and more Baby Boomers live into advanced old age. The global market is estimated to be worth $20 billion by the end of the decade. mark for My Articles similar articles
Chemistry World
June 9, 2010
Chemistry at Sussex under threat again The department, which topped The Guardian's 2010 university league table for chemistry, is set to lose some 40 per cent of its faculty, according to Phil Parsons, head of organic chemistry at Sussex. mark for My Articles similar articles
The Motley Fool
June 29, 2007
Brian Orelli
The Phase 2 Blues Drug developer Cytokinetics disappoints investors with failed clinical trials. mark for My Articles similar articles
Bio-IT World
March 2006
Kevin Davies
Clinical Data Launches Landmark Trial Clinical Data has launched a Phase III clinical trial for the depression drug vilazodone and will concurrently develop a diagnostic test. The study could prove to be a landmark event in pharmacogenomic medicine. mark for My Articles similar articles