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Bio-IT World
April 2007
Vicki Glaser
Software Solutions for Medicinal Chemistry Driven by advances in chemical synthesis, instrumentation, and high-throughput and high-content screening technology, medicinal chemistry's transition from an art to a science is benefiting from a wealth of new software products, spanning both bio- and cheminformatics. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
Bio-IT World
November 12, 2002
James Golden
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. mark for My Articles similar articles
Chemistry World
August 13, 2015
Exploiting the data mine Chemists must embrace open data to allow us to collectively get the best out of the masses of new knowledge we unearth, reports Clare Sansom mark for My Articles similar articles
Bio-IT World
February 10, 2003
Malorye Branca
Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic. mark for My Articles similar articles
ONLINE
Sep/Oct 2007
Svetla Baykoucheva
A New Era in Chemical Information: PubChem, DiscoveryGate, and Chemistry Central How the emergence of PubChem, DiscoveryGate and Chemistry Central are changing the field of chemical information. mark for My Articles similar articles
Bio-IT World
June 17, 2004
John Garvey
Rational Decisions As companies in the computationally guided rational drug design sector mature, they should be more sure of the boundaries that surround their proprietary technologies. mark for My Articles similar articles
CIO
October 15, 2001
Stephanie Overby
Drug Companies on speed The marriage of IT and medical research may be just what traditional pharmaceutical companies need to survive in an increasingly competitive field. Learn how IT is bringing the pharmaceutical industry into the information age... mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Informatics Black Boxes ... Not! Vertex's chief technical officer, discusses informatics' bad reputation, buying vs. building, open-source tools, and ROI on IT. mark for My Articles similar articles
Bio-IT World
April 2006
John Russell
Pfizer's Pursuit of Technology Can this $50-billion-plus, 115,000-employee behemoth succeed where other pharma giants have failed and successfully institutionalize the effort to find and develop critical new technology? Should it even try? mark for My Articles similar articles
Bio-IT World
December 10, 2002
Arielle Emmett
Locus Focus Cheminformatics company Locus Discovery is a technology darling and an entrepreneur's dream, but it faces a dilemma over how much of its proprietary drug discovery software and data to reveal. mark for My Articles similar articles
Chemistry World
December 2008
Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project. mark for My Articles similar articles
Chemistry World
March 5, 2015
Emma Stoye
Forgotten synthetic PhD theses set to be given new lease of life A team of researchers have amassed a digital collection of more than 75,000 compounds from PhD theses that might otherwise have mouldered in obscurity. mark for My Articles similar articles
Bio-IT World
January 13, 2003
Michael Gross
Profiting from the Proteome Inpharmatica sells data products, but it also wants to discover drugs. mark for My Articles similar articles
Bio-IT World
April 16, 2004
Malorye Branca
Finding the Perfect Fit Fragment-based drug discovery is unique and effective. mark for My Articles similar articles
Chemistry World
January 2012
Rising interest in compound bank David Fox argues for the creation of a centralized repository for small molecules to harness research efforts in drug discovery mark for My Articles similar articles
Bio-IT World
November 2006
Kevin Davies
Jubilant Curries Favor with BioPharma The explosion of drug discovery and development operations in India is epitomized by the success of several companies. Quietly building on a decade of experience in computational and bio-IT fields, JBL is rapidly pushing into a suite of drug discovery and development activities. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Bio-IT World
October 9, 2002
Kevin Davies
Cracking the 'Druggable Genome' How many potential drug targets are encoded in the human genome? It is a crucial question for every biopharma business. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Chemistry World
July 26, 2012
Derek Lowe
Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time. mark for My Articles similar articles
Chemistry World
April 25, 2013
Andreas Barth
Chemical bibliometrics Counting compounds instead of publications and citations opens new perspectives for data-based scientific discovery and it can complement and stimulate both experimental and theoretical research. mark for My Articles similar articles
Chemistry World
October 2010
Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery mark for My Articles similar articles
Bio-IT World
February 2007
Bio*IT World's Coming Attractions 2007 Bio-IT World Conference & Expo preview -- Meet the Keynotes... Oracle Users... Systems are Go... Candid Camera... A Vital IT Alliance... Next Generation Informatics... etc. mark for My Articles similar articles
Pharmaceutical Executive
February 1, 2006
Ron Feemster
Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets. mark for My Articles similar articles
Chemistry World
May 31, 2009
Nina Notman
The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used. mark for My Articles similar articles
Bio-IT World
April 16, 2004
Kevin Davies
The Matrix Revolutions Serenex, a company dedicated to drug discovery, uses a proprietary matrix, or affinity media, to bind purine-binding protiens - a process that could transform the drug discovery business. mark for My Articles similar articles
Bio-IT World
November 14, 2003
Malorye Branca
Genomics Provides the Kick Inside New tools and business structures show signs of plumping early-stage pipelines. mark for My Articles similar articles
Chemistry World
April 2011
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good. mark for My Articles similar articles
Chemistry World
September 29, 2015
Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make? mark for My Articles similar articles
Chemistry World
July 2010
Column: In the pipeline Derek Lowe ponders the possibility of phosphatase inhibitors mark for My Articles similar articles
Chemistry World
December 16, 2013
Anthony King
Database of 15 million chemical structures set free A collection of over 15 million chemical structures from patents -- SureChem -- is to be made freely available through the European Bioinformatics Institute. mark for My Articles similar articles
Chemistry World
June 2010
Column: In the pipeline Derek Lowe looks into his crystal ball to see what the future of medicinal chemistry might be mark for My Articles similar articles
Chemistry World
December 2007
Derek Lowe
Column: In the Pipeline The challenge of biologics. mark for My Articles similar articles
Chemistry World
May 20, 2015
Katrina Kramer
Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs. mark for My Articles similar articles
The Motley Fool
July 6, 2010
Luke Timmerman
Rising From the Ashes of Pfizer: The Michigan Contract Research Organization Cluster Many of the people who honed their skills inside Pfizer and other big companies have found new entrepreneurial outlets to keep doing what they do best at a growing array of contract research organizations. mark for My Articles similar articles
Chemistry World
August 2009
Derek Lowe
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder mark for My Articles similar articles
Chemistry World
December 2007
Richard Van Noorden
Surfing Web2O The rapid evolution of the world wide web is creating fresh opportunities - and challenges - for chemistry. mark for My Articles similar articles
Bio-IT World
March 10, 2003
Mark D. Uehling
Technology Overload Inundated with new IT tools and mountains of data, the pharmaceutical industry struggles to pull it all together. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Jeffrey Skolnick
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. mark for My Articles similar articles
Bio-IT World
August 18, 2004
Kevin Davies
In Praise of Chemical Diversity How to build better small-molecule libraries. mark for My Articles similar articles
Chemistry World
December 19, 2011
Rebecca Trager
US agencies collaborate to test 10,000 chemicals A high-speed robotic screening system jointly initiated by three key US health agencies began testing more than 10,000 chemical compounds for potential toxicity on 7 December. mark for My Articles similar articles
Bio-IT World
September 2006
John Russell
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. mark for My Articles similar articles
Chemistry World
November 2, 2009
Simon Hadlington
New way to find drugs' unintended targets Researchers in the US have devised a new way to predict 'off-target' effects for pharmaceutical drugs. mark for My Articles similar articles
Chemistry World
December 1, 2014
Derek Lowe
Progress at the pace of the slowest Chemistry is a means to an end in drug research, not an end in itself, and that can take some getting used to. It's worth thinking about where chemistry fits into the big picture. mark for My Articles similar articles
Bio-IT World
November 2006
Wendy Wolfson
Oracle OpenWorld 2006: Pharma Stuck on Semantic Web At the recent Oracle OpenWorld conference, pharma executives offered evidence that some, at least, are using the semantic web to work smarter and lower drug development costs. mark for My Articles similar articles
Bio-IT World
August 13, 2002
Malorye Branca
The Proteomics Odyssey Efforts to map the constellation of protein interactions in humans gather momentum as companies vie to provide tools to capitalize on the potential of proteomics. But can proteomics prevail where some feel genomics has failed? mark for My Articles similar articles
Information Today
September 10, 2001
Robert E. Buntrock
CAS Announces New Features and Improvements at Recent ACS Meeting Although these developments are of primary importance to chemists, I should point out that chemistry is indeed "the central science." Both the science and its unique information-handling challenges are relevant to applications and technologies affecting all of us... mark for My Articles similar articles
Chemistry World
June 23, 2015
Derek Lowe
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. mark for My Articles similar articles
Chemistry World
December 17, 2012
Patrick Walter
RSC acquires rights to Merck Index The Royal Society of Chemistry has acquired the rights to the 'bible' of chemistry, the Merck Index, familiar around the world to medicinal chemists and drug discovery scientists. mark for My Articles similar articles