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HHMI Bulletin
Nov 2011
Sarah C. P. Williams
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. mark for My Articles similar articles
Chemistry World
July 6, 2012
Protein power Tom Muir, professor of chemistry and molecular biology, Princeton University, US, is an expert in protein engineering and its application to studying cellular signalling networks. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C.P. Williams.
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Malorye Branca
Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic. mark for My Articles similar articles
Chemistry World
September 13, 2012
Andy Merritt
Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Robert Tjian
President's Letter: Intellectual Ferment There are exciting connections between chemistry and biology from both "sides" of the disciplinary divide. mark for My Articles similar articles
Chemistry World
January 4, 2007
Henry Nicholls
Microscopic Lab Investigates Contents of a Cell It's small-scale science that could have a massive impact on research into cell biology. Scientists have produced a microscopic laboratory where they can count individual proteins in a single cell. mark for My Articles similar articles
HHMI Bulletin
February 2011
Sarah C.P. Williams
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. mark for My Articles similar articles
Chemistry World
April 26, 2009
Simon Hadlington
Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property mark for My Articles similar articles
Chemistry World
February 2012
Column: The crucible To understand the chemical choreography of the cell, we must acknowledge the bustling biomolecular ballroom in which it takes place, says Philip Ball mark for My Articles similar articles
Industrial Physicist
Apr/May 2003
Jennifer Oullette
Switching from physics to biology Physicists in transition help shape biological theory. mark for My Articles similar articles
Chemistry World
September 4, 2013
Mark Peplow
Synthetic biology is bursting with life The field encompasses a vast array of research themes, from creating artificial life to engineering microbes to produce medicines or fuels. Through it all, though, runs a rich seam of chemistry. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Chemistry World
July 2008
Mark Peplow
Editorial: There's plenty of room in the middle Today, chemists and biologists are looking at the space between their own disciplines and asking big questions about where science at the interface might lead them. mark for My Articles similar articles
Chemistry World
July 2008
Ananyo Bhattacharya
Sparks of creation Chemists are at the forefront of synthetic biology, the burgeoning field that could soon create artificial life. mark for My Articles similar articles
Chemistry World
May 1, 2014
Ned Stafford
Synthetic biology vision for Europe unveiled A new 'strategic vision' for synthetic biology has laid out the steps Europe needs to take in the next five to 10 year to nurture the field, with chemistry a key part of its strategy. mark for My Articles similar articles
HHMI Bulletin
Fall 2012
R. John Davenport
Hanchuan Peng: SmartScopes Even when he launched his career as an engineer and computer scientist, Hanchuan Peng was drawn to the beauty of biology. He is a leader in developing sophisticated ways to make sense of biological images. mark for My Articles similar articles
Chemistry World
September 24, 2013
Jennifer Newton
Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products. mark for My Articles similar articles
Chemistry World
January 10, 2008
Simon Hadlington
Proton Joins Elite Club of Cellular Messengers Researchers have discovered a new chemical that carries messages rapidly between cells - the first for more than 20 years. But unlike conventional signalling molecules, this is a far simpler chemical entity: it is the humble proton. mark for My Articles similar articles
IEEE Spectrum
March 2011
Lucks & Arkin
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering mark for My Articles similar articles
HHMI Bulletin
Aug 2011
Cassandra Willyard
A Faster Knockout With a virus, a needle, and an ultrasound machine, researchers have drastically cut the time it takes to disable a gene in mice. mark for My Articles similar articles
HHMI Bulletin
Spring 2013
Nicole Kresge
A Structural Toolbox Natalie Strynadka wants to design a better antibiotic. Her strategy: learn about the molecules bacteria use to invade cells. Her tool: structural biology. mark for My Articles similar articles
Chemistry World
April 20, 2009
James Urquhart
New method reveals small molecule-RNA conjugates US scientists using novel chemical screening methods have discovered a new class of small molecules connected to RNA, suggesting that cellular RNA may be more chemically diverse than previously thought. mark for My Articles similar articles
HHMI Bulletin
Aug 2011
Janelle Weaver
Leading a Double Life with CSF Lucky for us, the organs in our bodies come with a self-repair kit. Though regularly bombarded by harmful bacteria, more often than not they manage to heal themselves. How this happens has puzzled scientists, but now there may be some answers. mark for My Articles similar articles
Chemistry World
January 2012
Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues. mark for My Articles similar articles
Chemistry World
November 12, 2009
Hayley Birch
New drug design looks top Notch against cancer A new type of drug that can block the switching on of certain genes in cancer cells has shown promise in mice. mark for My Articles similar articles
Wired
August 2004
Oliver Morton
A Machine With a Mind of Its Own Ross King wanted a research assistant who would work 24/7 without sleep or food. So he built one. King's robot can look at the results of a biology experiment, draw a conclusion about what the results might mean, and then set off to test that conclusion. mark for My Articles similar articles
Wired
January 2005
Oliver Morton
Life, Reinvented A group of MIT engineers wanted to model the biological world. But, damn, some of nature's designs were complicated! So they started rebuilding from the ground up - and gave birth to synthetic biology. mark for My Articles similar articles
Industrial Physicist
Jennifer Ouellette
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems mark for My Articles similar articles
HHMI Bulletin
Aug 2010
Sarah C.P. Williams
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. mark for My Articles similar articles
Bio-IT World
September 2006
John Russell
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. mark for My Articles similar articles
Bio-IT World
December 15, 2003
Zachary Zimmerman
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. mark for My Articles similar articles
Chemistry World
June 23, 2015
Derek Lowe
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. mark for My Articles similar articles
Chemistry World
March 16, 2011
Inspirational science Seong Keun Kim is head of the Molecular Reaction Dynamics Laboratory at Seoul National University, Korea. He uses spectroscopic, microscopic and computational methods to investigate a wide range of subjects from molecular physics and nanoscience to cell biology. mark for My Articles similar articles
Bio-IT World
September 2006
Nat Goodman
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. mark for My Articles similar articles
Chemistry World
October 27, 2006
Richard Van Noorden
Synthetic Origami Folds Like Natural Enzymes Researchers have synthesised a large organic molecule that folds up like a small protein, though its backbone is entirely non-biological. The achievement is a step along the path to producing truly synthetic enzymes in the laboratory. mark for My Articles similar articles
HHMI Bulletin
Fall 2012
Elise Lamar
Push and Pull Jennifer Zallen, an HHMI early career scientist at Memorial Sloan-Kettering Cancer Center, studies how embryonic tissues stretch along an anterior-posterior axis using the fruit fly Drosophila melanogaster as a model system. mark for My Articles similar articles
Chemistry World
June 20, 2013
Jim Al-Khalili
Change: the only constant Today, there is much interest in a wide range of biological phenomena that may have a quantum origin, from our sense of smell to photosynthesis and mutations in DNA. mark for My Articles similar articles
Bio-IT World
August 18, 2004
Kevin Davies
In Praise of Chemical Diversity How to build better small-molecule libraries. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Hillel Alpert
Bio-IT Shines Bright in Israel Companies such as Quark and Pharmos are still flourishing as other industries decline in this country torn by conflict. mark for My Articles similar articles
Chemistry World
December 2007
Derek Lowe
Column: In the Pipeline The challenge of biologics. mark for My Articles similar articles
Bio-IT World
December 15, 2003
Malorye A. Branca
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful. mark for My Articles similar articles
Chemistry World
September 10, 2008
Simon Hadlington
Failed anxiety drug could treat cancer Scientists believe they have solved the mystery of how a drug originally developed for treating anxiety can kill cancer cells. mark for My Articles similar articles
HHMI Bulletin
Winter 2013
Nicole Kresge
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
BusinessWeek
May 16, 2005
Arlene Weintraub
Bristling With Promise Start-up Curis is developing a class of drugs that could halt hair loss -- and treat cancer mark for My Articles similar articles
Bio-IT World
November 2006
Robert M. Frederickson
Managing Data on the Go GeneGo has created a suite of software and database products that aim to facilitate analysis of the biology behind different types of high-throughput experimentation and understand the effects of small molecule drug compounds in human tissues. mark for My Articles similar articles
Chemistry World
February 12, 2014
Manisha Lalloo
Synthetic strategy targets 'undruggable' small RNAs Chemists in the US have found a way to predict small molecules that can target short pieces of RNA involved in some diseases, such as cancer. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles