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Chemistry World
May 28, 2012
Sarah Houlton
HDL drug class struggling after latest flop The failure of dalcetrapib, a drug from Roche designed to raise HDL, or 'good', cholesterol, has turned the spotlight again on such drugs. mark for My Articles similar articles
The Motley Fool
December 1, 2009
Robert Steyer
Merck Makes a Mark on Good Cholesterol Can't profit from fighting bad lipoproteins? Start boosting the good ones. mark for My Articles similar articles
The Motley Fool
October 5, 2007
Brian Orelli
Merck's Next Blockbuster? Merck's cholesterol drug comes back from phase 2 testing with no side effects. Investors, take note. mark for My Articles similar articles
The Motley Fool
August 24, 2011
Brian Orelli
Can Roche and Merck Succeed Where Pfizer Failed? CETP inhibitors are lucrative but risky. mark for My Articles similar articles
BusinessWeek
November 24, 2010
Tom Randall
Merck May Have a Cholesterol Winner Merck told doctors at the American Heart Assn. annual meeting that new data showed its drug anacetrapib had reduced bad cholesterol by 40 percent while raising good cholesterol by an unprecedented 138 percent. mark for My Articles similar articles
The Motley Fool
December 4, 2006
Michael P. Cecil
Pfizer's Cholesterol-Drug Hopes Crumble In surprising and disappointing news, the pharma's promising new drug fails clinical trials. With Pfizer shares declining because of the bad news, is now a good time to buy? mark for My Articles similar articles
Chemistry World
January 2007
Derek Lowe
Opinion: In the Pipeline Here is a look at the recent failure of Pfizer's cholesterol drug, torcetrapib, and what it could mean for the future of pharmaceutical research. mark for My Articles similar articles
The Motley Fool
December 23, 2003
Arash Mostaghimi
The Cholesterol Wars Who will win the fight to save your arteries? Fortunately for our corpulent country, pharmaceutical companies want to unclog our arteries -- and lighten our wallets. But which pharma stock will add to most girth to a portfolio? mark for My Articles similar articles
The Motley Fool
December 30, 2003
Arash Mostaghimi
Turning Cholesterol Into Cash With 62 million Americans suffering from heart disease, it's a huge target for major drug makers. mark for My Articles similar articles
The Motley Fool
November 15, 2011
Brian Orelli
Good Data, Big Drug Market, but Still Risky Eli Lilly's evacetrapib is behind Roche and Merck. mark for My Articles similar articles
BusinessWeek
March 11, 2010
Ellen Gibson
The Quest to Boost Good Cholesterol Cleveland Clinic's Steven Nissen is again pursuing a drug that will attack plaque by raising HDL. mark for My Articles similar articles
The Motley Fool
August 30, 2007
Brian Orelli
Merck Tries to Stop the Flushing The FDA will review the pharma's new cholesterol drug. The biggest worry with getting CORDAPTIVE approved is probably not with its effectiveness, but with safety. Investors, take note. mark for My Articles similar articles
BusinessWeek
April 19, 2004
Catherine Arnst
Cholesterol: How Low Should It Be? New studies say as low as possible, but drugs aren't for everybody mark for My Articles similar articles
American Family Physician
January 15, 2001
Goals for Lowering Your Cholesterol Why is it important to have a normal cholesterol level?... What does the term "total cholesterol" mean?... Why is LDL called the "bad" cholesterol?... What are normal cholesterol levels?... How can I reduce my LDL and total cholesterol levels?... etc. mark for My Articles similar articles
BusinessWeek
March 11, 2010
Four Ways to Raise HDL Four different routes to raising good cholesterol. mark for My Articles similar articles
American Family Physician
March 1, 2002
Richard S. Safeer
Cholesterol Treatment Guidelines Update In addition to modifying current strategies of risk assessment, the new guidelines stress the importance of an aggressive therapeutic approach in the management of hypercholesterolemia... mark for My Articles similar articles
BusinessWeek
December 13, 2004
Kate Murphy
Cholesterol: The Bigger the Better Many doctors are convinced that getting a more thorough cholesterol test, one that identifies the types of LDL particles, can improve treatment and save lives. mark for My Articles similar articles
The Motley Fool
December 12, 2007
Brian Orelli
What's Merck Doing? With a nice solid pipeline Merck is on its way to its goal of double-digit EPS growth through 2010. mark for My Articles similar articles
American Family Physician
April 15, 2003
Cholesterol What is cholesterol?... Why is a high cholesterol level unhealthy?... When should I start having my cholesterol level checked?... Are there different kinds of cholesterol?... What can I do to improve my cholesterol level?... etc. mark for My Articles similar articles
Pharmaceutical Executive
December 1, 2010
Walter Armstrong
The Next Wave: Pharm Exec's 2011 Pipeline Report 42 of the best new drugs in development or parked at the FDA mark for My Articles similar articles
HHMI Bulletin
May 2011
Sarah C. P. Williams
The Next Statin Although clinicians have firmly established the link between cholesterol levels and heart disease, there are still more questions than answers when it comes to the nitty-gritty molecular details of this connection. mark for My Articles similar articles
The Motley Fool
September 24, 2010
Brian Orelli
Prepare for This $12 Billion Whoosh Pfizer's Lipitor is the top-selling cholesterol drug -- in fact, it's the top selling drug period -- but it'll start to see generic competition in a little over a year. mark for My Articles similar articles
The Motley Fool
May 20, 2009
Brian Orelli
Clinical Trial Positive, Stock Not So Much Isis and Genzyme hit a homer with their cholesterol drug, mipomersen, but they'll need another big play to win the game. mark for My Articles similar articles
The Motley Fool
November 16, 2009
Brian Orelli
Abbott Puts a Nail in Merck's Coffin There's a clear winner from the American Heart Association conference. mark for My Articles similar articles
The Motley Fool
January 27, 2004
David Nierengarten
Pfizer's Next Target? Esperion, swallowed by Pfizer last year, shares many similarities with Atherogenics. Investors in the latter, however, should not count on being acquired any time soon by a big pharmaceutical company. mark for My Articles similar articles
The Motley Fool
March 14, 2006
Brian Gorman
AstraZeneca's Heartening News A new study shows cholesterol drug Crestor's further potential. Will it help sales? mark for My Articles similar articles
BusinessWeek
July 21, 2003
Amy Barrett
A Bare-Knuckle Battle over Cholesterol Drugs If AstraZeneca's Crestor is approved, rivals' stepped-up pitches will focus on safety mark for My Articles similar articles
American Family Physician
January 15, 2002
Lori J. Mosca
Optimal Management of Cholesterol Levels and the Prevention of Coronary Heart Disease in Women Elevated levels of low-density lipoprotein cholesterol and triglycerides and low levels of high-density lipoprotein cholesterol are significant risk factors for coronary heart disease. Abundant data show inadequate utilization of lipid-lowering therapy in women... mark for My Articles similar articles
The Motley Fool
April 29, 2008
Brian Orelli
Merck's Recovery Flushed Down Merck's best hope at recovery fails approval by the FDA. mark for My Articles similar articles
BusinessWeek
July 26, 2004
Amy Barrett
Hooked On The Cash From Cholesterol Cholesterol-lowering drugs are massive moneyspinners. But can big pharmaceutical companies sidestep expiring patents? mark for My Articles similar articles
Health
January 2008
Jessica Snyder Sachs
What You Must Know About Your Cholesterol Many of us are in the danger zone, and we don't realize it. What can we start to do right now to change that? mark for My Articles similar articles
Chemistry World
May 2008
Derek Lowe
In the pipeline The controversy over cholesterol drug Vytorin has been going on for months. Surveying the wreckage, my first thought is: what a terrible shame the whole affair is. mark for My Articles similar articles
Scientific American
April 2005
Diane Martindale
Reactive Reasoning Is an inflammation protein the next cholesterol? mark for My Articles similar articles
Managed Care
April 2004
Jack McCain
Statin Therapy: More Than Meets the Eye? Statin selection has just become more complicated. Will physicians be diverted from interventions that may be less costly and just as effective? mark for My Articles similar articles
Pharmaceutical Executive
October 1, 2006
Rob Scott
Thoughtleader: Life After Lipitor A conversation with a former Pfizer executive who "launched the world's best-selling drug." mark for My Articles similar articles
The Motley Fool
April 2, 2008
Michael P. Cecil
Irrational Exuberance for Vytorin and Zetia? Drugmakers Merck and Schering-Plough certainly hoped data from the Enhance study would enhance the value and status of their blockbuster cholesterol-fighting drugs Zetia and Vytorin -- but its results did quite the opposite. mark for My Articles similar articles
The Motley Fool
November 22, 2010
Brian Orelli
Let's Call It a Partial Victory Merck's Vytorin works better than a placebo. Unfortunately, it may be too little and too late to do anything about the sales cut that Vytorin has taken over the past few years. mark for My Articles similar articles
Chemistry World
August 23, 2007
Richard Van Noorden
How Good Cholesterol Turns Bad Chemists have peered into the depths of HDL, which protects against heart disease, to explain why it can become harmful. The research may also suggest an explanation for the near-billion-dollar failure of Pfizer's blockbuster heart drug, torcetrapib, in recent clinical trials. mark for My Articles similar articles
American Family Physician
January 15, 2001
Michael A. Crouch
Effective Use of Statins to Prevent Coronary Heart Disease Primary and secondary prevention trials have shown that use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (also known as statins) to lower an elevated low-density lipoprotein level can substantially reduce coronary events and death from coronary heart disease... mark for My Articles similar articles
The Motley Fool
January 15, 2008
Brian Orelli
No Enhance-ment From Zetia Merck and Schering report bad news, but how much will it affect sales? Investors, take note. mark for My Articles similar articles
The Motley Fool
January 17, 2008
Michael P. Cecil
2 Sources of Trouble for Vytorin You know that a drug study has gone very, very bad when you can't find out its results without a congressional inquiry. mark for My Articles similar articles
The Motley Fool
August 5, 2010
Brian Orelli
Blockbuster Efficacy! Not-So-Blockbuster Safety! Isis and Genzyme's wonder drug has not-so-wonderful side effects. Still. mark for My Articles similar articles
American Family Physician
December 15, 2000
Alan J. Garber
Attenuating Cardiovascular Risk Factors in Patients with Type 2 Diabetes All cardiovascular risk factors except smoking are more prevalent in patients with type 2 diabetes. In addition to exercise, weight control, aspirin therapy and blood pressure control, therapy to modify lipid profiles is usually necessary... mark for My Articles similar articles
The Motley Fool
May 27, 2011
Brian Orelli
AIM-HIGH? These Drugmakers Better Duck. A government study on cholesterol drugs hurts Abbott and Merck. mark for My Articles similar articles
BusinessWeek
March 6, 2006
Amy Barrett
Merck: Out Of The Ivory Tower Merck's pragmatic strategy includes tweaking the vitamin niacin to make it a blockbuster. mark for My Articles similar articles
The Motley Fool
June 27, 2005
Brian Gorman
Pfizer's Controversial Pairing The pharmaceutical's strategy of combining an experimental medicine with Lipitor will likely come under increasing fire. Investors, take note. mark for My Articles similar articles
The Motley Fool
April 18, 2011
Brian Orelli
Up 95%! No Anchor Holding Amarin Down The second phase 3 trial of AMR101 deemed a success. mark for My Articles similar articles
The Motley Fool
December 4, 2008
Brian Orelli
Pfizer Blows Statin Smoke Pfizer presents some mildly persuasive numbers to try to win back customers for Lipitor. mark for My Articles similar articles
Managed Care
November 2004
Martin Sipkoff
OTC Status for Low-Dose Lovastatin Would Have Widespread Implications The FDA stands poised to approve OTC low-dose statins, following a similar change in United Kingdom. mark for My Articles similar articles
Pharmaceutical Executive
December 1, 2006
Pipeline 32 compounds that are the early fruit of pharma's investment in targeted drug design. mark for My Articles similar articles