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The Motley Fool
December 4, 2006
Michael P. Cecil
Pfizer's Cholesterol-Drug Hopes Crumble In surprising and disappointing news, the pharma's promising new drug fails clinical trials. With Pfizer shares declining because of the bad news, is now a good time to buy? mark for My Articles similar articles
The Motley Fool
August 24, 2011
Brian Orelli
Can Roche and Merck Succeed Where Pfizer Failed? CETP inhibitors are lucrative but risky. mark for My Articles similar articles
The Motley Fool
June 27, 2005
Brian Gorman
Pfizer's Controversial Pairing The pharmaceutical's strategy of combining an experimental medicine with Lipitor will likely come under increasing fire. Investors, take note. mark for My Articles similar articles
The Motley Fool
May 21, 2010
Brian Orelli
And You Thought Biotech Was High-Risk, High-Reward Large clinical trials make cardiovascular drugs risky, but the rewards are there, too. mark for My Articles similar articles
Chemistry World
May 28, 2012
Sarah Houlton
HDL drug class struggling after latest flop The failure of dalcetrapib, a drug from Roche designed to raise HDL, or 'good', cholesterol, has turned the spotlight again on such drugs. mark for My Articles similar articles
The Motley Fool
October 5, 2007
Brian Orelli
Merck's Next Blockbuster? Merck's cholesterol drug comes back from phase 2 testing with no side effects. Investors, take note. mark for My Articles similar articles
The Motley Fool
December 1, 2009
Robert Steyer
Merck Makes a Mark on Good Cholesterol Can't profit from fighting bad lipoproteins? Start boosting the good ones. mark for My Articles similar articles
Pharmaceutical Executive
December 1, 2010
Walter Armstrong
Hyperlipidemia: The Anti-CETPs Redux The crowded cholesterol-control category is the biggest US drug market, with 2010 global sales close to $35 billion, according to IMS Health. mark for My Articles similar articles
BusinessWeek
March 11, 2010
Ellen Gibson
The Quest to Boost Good Cholesterol Cleveland Clinic's Steven Nissen is again pursuing a drug that will attack plaque by raising HDL. mark for My Articles similar articles
The Motley Fool
November 15, 2011
Brian Orelli
Good Data, Big Drug Market, but Still Risky Eli Lilly's evacetrapib is behind Roche and Merck. mark for My Articles similar articles
BusinessWeek
November 24, 2010
Tom Randall
Merck May Have a Cholesterol Winner Merck told doctors at the American Heart Assn. annual meeting that new data showed its drug anacetrapib had reduced bad cholesterol by 40 percent while raising good cholesterol by an unprecedented 138 percent. mark for My Articles similar articles
The Motley Fool
August 23, 2004
Ben McClure
Rethinking Big Pharma Risk is knocking Big Pharma stocks down. They won't be getting up anytime soon. Competition, soaring R&D costs, shifting business models, and political meddling combine to make drug stocks a riskier place to invest. mark for My Articles similar articles
BusinessWeek
May 27, 2010
Michelle Cortez
Karo Bio's Prescription: Cheaper Drug Approval A Swedish company seeks a lower-cost review for its cholesterol drug. mark for My Articles similar articles
Chemistry World
August 23, 2007
Richard Van Noorden
How Good Cholesterol Turns Bad Chemists have peered into the depths of HDL, which protects against heart disease, to explain why it can become harmful. The research may also suggest an explanation for the near-billion-dollar failure of Pfizer's blockbuster heart drug, torcetrapib, in recent clinical trials. mark for My Articles similar articles
The Motley Fool
December 30, 2003
Arash Mostaghimi
Turning Cholesterol Into Cash With 62 million Americans suffering from heart disease, it's a huge target for major drug makers. mark for My Articles similar articles
The Motley Fool
December 4, 2006
Michael Leibert
Whither Pfizer? Bad news follows the upbeat message delivered at Pfizer's R&D briefing. But with strong cash flows, a healthy dividend yield, unparalleled scale, and a discounted share price, Pfizer's risk/reward profile might look attractive to investors. mark for My Articles similar articles
The Motley Fool
July 12, 2010
Ryan McBride
Synta Pharma CEO Trumpets New Top Cancer Drug Synta Pharmaceuticals has been climbing back from one of the Boston area's highest-profile clinical trial failures of 2009. mark for My Articles similar articles
The Motley Fool
February 22, 2007
Brian Lawler
Dueling Fools: Pfizer Bear It's been a blue chip for years, but that doesn't mean it will stay that way forever. It's inconceivable for Pfizer's market capitalization to be valued at $188 billion four years from now, when its revenues could be 40% lower than they are today. mark for My Articles similar articles
BusinessWeek
March 11, 2010
Four Ways to Raise HDL Four different routes to raising good cholesterol. mark for My Articles similar articles
The Motley Fool
March 3, 2010
Brian Orelli
A Costly Missed Connection Dimebon's phase 3 failure costs Medivation shareholders 67%. mark for My Articles similar articles
The Motley Fool
September 24, 2010
Brian Orelli
Prepare for This $12 Billion Whoosh Pfizer's Lipitor is the top-selling cholesterol drug -- in fact, it's the top selling drug period -- but it'll start to see generic competition in a little over a year. mark for My Articles similar articles
The Motley Fool
December 23, 2003
Arash Mostaghimi
The Cholesterol Wars Who will win the fight to save your arteries? Fortunately for our corpulent country, pharmaceutical companies want to unclog our arteries -- and lighten our wallets. But which pharma stock will add to most girth to a portfolio? mark for My Articles similar articles
Chemistry World
November 2010
Column: In the Pipeline Should drug companies focus on big markets and the blockbuster dream? mark for My Articles similar articles
The Motley Fool
January 8, 2010
Brian Orelli
Pfizer's Having a Garage Sale Rather than sending its unwanted drugs to the trash bin, the giant drugmaker is striking deals with its comrades to take them off its hands. mark for My Articles similar articles
The Motley Fool
March 4, 2010
Brian Orelli
A Painless Drug Deal Bristol-Myers licenses pain drug from Allergan. mark for My Articles similar articles
BusinessWeek
July 26, 2004
Amy Barrett
Hooked On The Cash From Cholesterol Cholesterol-lowering drugs are massive moneyspinners. But can big pharmaceutical companies sidestep expiring patents? mark for My Articles similar articles
The Motley Fool
March 4, 2011
Brian Orelli
Pfizer's Biggest Shot at Lipitor 2.0 It might need a little help from competitors. mark for My Articles similar articles
The Motley Fool
November 22, 2010
Brian Orelli
Pfizer's Mixed Bag Pfizer had a mixed bag of clinical trial results at the end of last week. And probably the company would have rather seen the results flip-flopped. mark for My Articles similar articles
The Motley Fool
December 29, 2009
Brian Orelli
Some Brand-Name Patents: Going, Going, Gone in 2010 Generic drug competition is coming for Lipitor, Plavix, and others. mark for My Articles similar articles
Pharmaceutical Executive
October 1, 2006
Rob Scott
Thoughtleader: Life After Lipitor A conversation with a former Pfizer executive who "launched the world's best-selling drug." mark for My Articles similar articles
Pharmaceutical Executive
December 1, 2005
Ron Feemster
The PharmExec 2005 Pipeline Report Dry? Not quite. Instead of 1990s-style blockbusters, pharma's new molecules are niche drugs, cancer treatments and -- at last -- innovative mechanisms for troublesome targets: Acomplia [rimonabant] by Sanofi-Aventis... AMG 162 [denosumab] by Amgen... etc. mark for My Articles similar articles
The Motley Fool
April 26, 2011
Brian Orelli
We Hate Your Drug. And That's a Good Thing. This one's a pain for the clinical trial participants. mark for My Articles similar articles
The Motley Fool
July 30, 2010
Brian Orelli
3 Development-Stage Drugmakers Worth Watching A basket of potential drugs in just one company. mark for My Articles similar articles
Chemistry World
March 2011
Column: In the pipeline Drug discovery is an inherently risky business. Derek Lowe tries to balance some of the risk equations mark for My Articles similar articles
BusinessWeek
February 28, 2005
Amy Barrett
Pfizer Is "At a Fork in the Road" CEO Henry McKinnell discusses the drugmaker's outlook, from new products and advertising to the challenges facing health care. mark for My Articles similar articles
The Motley Fool
January 29, 2010
Brian Orelli
How to Make Billions of Dollars Without Really Trying Lackluster Alzheimer's drugs have been doing it for years. mark for My Articles similar articles
The Motley Fool
December 1, 2011
John Grgurich
Pfizer Losing Lipitor Patent: What Investors Need to Know The patent ends today. mark for My Articles similar articles
The Motley Fool
August 2, 2004
Brian Gorman
Will Lipitor's Certification Boost Pfizer? The FDA's ruling may help the company ward off a new threat. mark for My Articles similar articles
The Motley Fool
May 11, 2010
Ryan McBride
Clinical Data Seeks to Challenge Lilly, Pfizer in Antidepressant Market The tiny drug developer has no problem going up against bigger rivals. mark for My Articles similar articles
Managed Care
April 2004
Jack McCain
Statin Therapy: More Than Meets the Eye? Statin selection has just become more complicated. Will physicians be diverted from interventions that may be less costly and just as effective? mark for My Articles similar articles
Chemistry World
September 2007
Derek Lowe
Column: In the Pipeline Will Phase Zero trials actually help drug development? mark for My Articles similar articles
The Motley Fool
December 22, 2003
Jeff Hwang
Pfizer Stuffs Its Pipeline Pfizer extends its reach in cardiovascular disease with Esperion Therapeutics. mark for My Articles similar articles
The Motley Fool
May 27, 2011
Brian Orelli
AIM-HIGH? These Drugmakers Better Duck. A government study on cholesterol drugs hurts Abbott and Merck. mark for My Articles similar articles
The Motley Fool
June 18, 2010
Brian Orelli
Hot Dog! No Competition for Now Roche's diabetes pipeline drug is delayed. mark for My Articles similar articles
The Motley Fool
March 29, 2010
Brian Orelli
Look for Companies That Strike First Head-to-head trials, whether they're run by companies or by third parties, can be scary. But the way to make big money is by selling drugs that offer superior benefits, so investors should welcome the onslaught of upcoming comparative trial data. mark for My Articles similar articles
The Motley Fool
March 25, 2011
Brian Orelli
Pfile Pfizer Under "Potential" Researchers reported promising finding from a clinical trial of Pfizer's new drug, CP-870,893, in pancreatic cancer patients in the most recent issue of the journal Science. mark for My Articles similar articles
BusinessWeek
March 6, 2006
Amy Barrett
Merck: Out Of The Ivory Tower Merck's pragmatic strategy includes tweaking the vitamin niacin to make it a blockbuster. mark for My Articles similar articles
The Motley Fool
February 25, 2009
Brian Orelli
Pfizer Doesn't Like Reruns The company drops two drugs that had made it as far as phase 3 trials. mark for My Articles similar articles
Chemistry World
July 2, 2013
Derek Lowe
Target acquired Phenotypic screening has recently seen a revival in popularity. This technique assesses drug candidates first by their effects in some organism, then works back to their causes. It can be an effective strategy, but when you find some interesting results, the need to explain them can become acute. mark for My Articles similar articles
HHMI Bulletin
May 2011
Sarah C. P. Williams
The Next Statin Although clinicians have firmly established the link between cholesterol levels and heart disease, there are still more questions than answers when it comes to the nitty-gritty molecular details of this connection. mark for My Articles similar articles