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The Motley Fool December 4, 2006 Michael P. Cecil |
Pfizer's Cholesterol-Drug Hopes Crumble In surprising and disappointing news, the pharma's promising new drug fails clinical trials. With Pfizer shares declining because of the bad news, is now a good time to buy? |
The Motley Fool August 24, 2011 Brian Orelli |
Can Roche and Merck Succeed Where Pfizer Failed? CETP inhibitors are lucrative but risky. |
The Motley Fool June 27, 2005 Brian Gorman |
Pfizer's Controversial Pairing The pharmaceutical's strategy of combining an experimental medicine with Lipitor will likely come under increasing fire. Investors, take note. |
The Motley Fool May 21, 2010 Brian Orelli |
And You Thought Biotech Was High-Risk, High-Reward Large clinical trials make cardiovascular drugs risky, but the rewards are there, too. |
Chemistry World May 28, 2012 Sarah Houlton |
HDL drug class struggling after latest flop The failure of dalcetrapib, a drug from Roche designed to raise HDL, or 'good', cholesterol, has turned the spotlight again on such drugs. |
The Motley Fool October 5, 2007 Brian Orelli |
Merck's Next Blockbuster? Merck's cholesterol drug comes back from phase 2 testing with no side effects. Investors, take note. |
The Motley Fool December 1, 2009 Robert Steyer |
Merck Makes a Mark on Good Cholesterol Can't profit from fighting bad lipoproteins? Start boosting the good ones. |
Pharmaceutical Executive December 1, 2010 Walter Armstrong |
Hyperlipidemia: The Anti-CETPs Redux The crowded cholesterol-control category is the biggest US drug market, with 2010 global sales close to $35 billion, according to IMS Health. |
BusinessWeek March 11, 2010 Ellen Gibson |
The Quest to Boost Good Cholesterol Cleveland Clinic's Steven Nissen is again pursuing a drug that will attack plaque by raising HDL. |
The Motley Fool November 15, 2011 Brian Orelli |
Good Data, Big Drug Market, but Still Risky Eli Lilly's evacetrapib is behind Roche and Merck. |
BusinessWeek November 24, 2010 Tom Randall |
Merck May Have a Cholesterol Winner Merck told doctors at the American Heart Assn. annual meeting that new data showed its drug anacetrapib had reduced bad cholesterol by 40 percent while raising good cholesterol by an unprecedented 138 percent. |
The Motley Fool August 23, 2004 Ben McClure |
Rethinking Big Pharma Risk is knocking Big Pharma stocks down. They won't be getting up anytime soon. Competition, soaring R&D costs, shifting business models, and political meddling combine to make drug stocks a riskier place to invest. |
BusinessWeek May 27, 2010 Michelle Cortez |
Karo Bio's Prescription: Cheaper Drug Approval A Swedish company seeks a lower-cost review for its cholesterol drug. |
Chemistry World August 23, 2007 Richard Van Noorden |
How Good Cholesterol Turns Bad Chemists have peered into the depths of HDL, which protects against heart disease, to explain why it can become harmful. The research may also suggest an explanation for the near-billion-dollar failure of Pfizer's blockbuster heart drug, torcetrapib, in recent clinical trials. |
The Motley Fool December 30, 2003 Arash Mostaghimi |
Turning Cholesterol Into Cash With 62 million Americans suffering from heart disease, it's a huge target for major drug makers. |
The Motley Fool December 4, 2006 Michael Leibert |
Whither Pfizer? Bad news follows the upbeat message delivered at Pfizer's R&D briefing. But with strong cash flows, a healthy dividend yield, unparalleled scale, and a discounted share price, Pfizer's risk/reward profile might look attractive to investors. |
The Motley Fool July 12, 2010 Ryan McBride |
Synta Pharma CEO Trumpets New Top Cancer Drug Synta Pharmaceuticals has been climbing back from one of the Boston area's highest-profile clinical trial failures of 2009. |
The Motley Fool February 22, 2007 Brian Lawler |
Dueling Fools: Pfizer Bear It's been a blue chip for years, but that doesn't mean it will stay that way forever. It's inconceivable for Pfizer's market capitalization to be valued at $188 billion four years from now, when its revenues could be 40% lower than they are today. |
BusinessWeek March 11, 2010 |
Four Ways to Raise HDL Four different routes to raising good cholesterol. |
The Motley Fool March 3, 2010 Brian Orelli |
A Costly Missed Connection Dimebon's phase 3 failure costs Medivation shareholders 67%. |
The Motley Fool September 24, 2010 Brian Orelli |
Prepare for This $12 Billion Whoosh Pfizer's Lipitor is the top-selling cholesterol drug -- in fact, it's the top selling drug period -- but it'll start to see generic competition in a little over a year. |
The Motley Fool December 23, 2003 Arash Mostaghimi |
The Cholesterol Wars Who will win the fight to save your arteries? Fortunately for our corpulent country, pharmaceutical companies want to unclog our arteries -- and lighten our wallets. But which pharma stock will add to most girth to a portfolio? |
Chemistry World November 2010 |
Column: In the Pipeline Should drug companies focus on big markets and the blockbuster dream? |
The Motley Fool January 8, 2010 Brian Orelli |
Pfizer's Having a Garage Sale Rather than sending its unwanted drugs to the trash bin, the giant drugmaker is striking deals with its comrades to take them off its hands. |
The Motley Fool March 4, 2010 Brian Orelli |
A Painless Drug Deal Bristol-Myers licenses pain drug from Allergan. |
BusinessWeek July 26, 2004 Amy Barrett |
Hooked On The Cash From Cholesterol Cholesterol-lowering drugs are massive moneyspinners. But can big pharmaceutical companies sidestep expiring patents? |
The Motley Fool March 4, 2011 Brian Orelli |
Pfizer's Biggest Shot at Lipitor 2.0 It might need a little help from competitors. |
The Motley Fool November 22, 2010 Brian Orelli |
Pfizer's Mixed Bag Pfizer had a mixed bag of clinical trial results at the end of last week. And probably the company would have rather seen the results flip-flopped. |
The Motley Fool December 29, 2009 Brian Orelli |
Some Brand-Name Patents: Going, Going, Gone in 2010 Generic drug competition is coming for Lipitor, Plavix, and others. |
Pharmaceutical Executive October 1, 2006 Rob Scott |
Thoughtleader: Life After Lipitor A conversation with a former Pfizer executive who "launched the world's best-selling drug." |
Pharmaceutical Executive December 1, 2005 Ron Feemster |
The PharmExec 2005 Pipeline Report Dry? Not quite. Instead of 1990s-style blockbusters, pharma's new molecules are niche drugs, cancer treatments and -- at last -- innovative mechanisms for troublesome targets: Acomplia [rimonabant] by Sanofi-Aventis... AMG 162 [denosumab] by Amgen... etc. |
The Motley Fool April 26, 2011 Brian Orelli |
We Hate Your Drug. And That's a Good Thing. This one's a pain for the clinical trial participants. |
The Motley Fool July 30, 2010 Brian Orelli |
3 Development-Stage Drugmakers Worth Watching A basket of potential drugs in just one company. |
Chemistry World March 2011 |
Column: In the pipeline Drug discovery is an inherently risky business. Derek Lowe tries to balance some of the risk equations |
BusinessWeek February 28, 2005 Amy Barrett |
Pfizer Is "At a Fork in the Road" CEO Henry McKinnell discusses the drugmaker's outlook, from new products and advertising to the challenges facing health care. |
The Motley Fool January 29, 2010 Brian Orelli |
How to Make Billions of Dollars Without Really Trying Lackluster Alzheimer's drugs have been doing it for years. |
The Motley Fool December 1, 2011 John Grgurich |
Pfizer Losing Lipitor Patent: What Investors Need to Know The patent ends today. |
The Motley Fool August 2, 2004 Brian Gorman |
Will Lipitor's Certification Boost Pfizer? The FDA's ruling may help the company ward off a new threat. |
The Motley Fool May 11, 2010 Ryan McBride |
Clinical Data Seeks to Challenge Lilly, Pfizer in Antidepressant Market The tiny drug developer has no problem going up against bigger rivals. |
Managed Care April 2004 Jack McCain |
Statin Therapy: More Than Meets the Eye? Statin selection has just become more complicated. Will physicians be diverted from interventions that may be less costly and just as effective? |
Chemistry World September 2007 Derek Lowe |
Column: In the Pipeline Will Phase Zero trials actually help drug development? |
The Motley Fool December 22, 2003 Jeff Hwang |
Pfizer Stuffs Its Pipeline Pfizer extends its reach in cardiovascular disease with Esperion Therapeutics. |
The Motley Fool May 27, 2011 Brian Orelli |
AIM-HIGH? These Drugmakers Better Duck. A government study on cholesterol drugs hurts Abbott and Merck. |
The Motley Fool June 18, 2010 Brian Orelli |
Hot Dog! No Competition for Now Roche's diabetes pipeline drug is delayed. |
The Motley Fool March 29, 2010 Brian Orelli |
Look for Companies That Strike First Head-to-head trials, whether they're run by companies or by third parties, can be scary. But the way to make big money is by selling drugs that offer superior benefits, so investors should welcome the onslaught of upcoming comparative trial data. |
The Motley Fool March 25, 2011 Brian Orelli |
Pfile Pfizer Under "Potential" Researchers reported promising finding from a clinical trial of Pfizer's new drug, CP-870,893, in pancreatic cancer patients in the most recent issue of the journal Science. |
BusinessWeek March 6, 2006 Amy Barrett |
Merck: Out Of The Ivory Tower Merck's pragmatic strategy includes tweaking the vitamin niacin to make it a blockbuster. |
The Motley Fool February 25, 2009 Brian Orelli |
Pfizer Doesn't Like Reruns The company drops two drugs that had made it as far as phase 3 trials. |
Chemistry World July 2, 2013 Derek Lowe |
Target acquired Phenotypic screening has recently seen a revival in popularity. This technique assesses drug candidates first by their effects in some organism, then works back to their causes. It can be an effective strategy, but when you find some interesting results, the need to explain them can become acute. |
HHMI Bulletin May 2011 Sarah C. P. Williams |
The Next Statin Although clinicians have firmly established the link between cholesterol levels and heart disease, there are still more questions than answers when it comes to the nitty-gritty molecular details of this connection. |