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Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World November 2010	Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize.
Chemistry World August 2008	Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now?
Chemistry World January 6, 2013 Simon Hadlington	Greener route to carboxylic acids Chemists in Israel have developed a new way to oxidize primary alcohols to carboxylic acids, using water as both the reaction solvent and the source of oxygen.
Chemistry World July 10, 2013 Karl Collins	An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort.
Chemistry World January 25, 2013 Derek Lowe	Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers?
Chemistry World November 5, 2013 Paul Docherty	Marcfortines B & C Natural product isolation is generally a tale of a journey to an obscure or inaccessible location, followed by pulping a harmless plant or marine sponge to get at compounds made by some bacteria hiding out in the core.
Chemistry World February 2008 Dylan Stiles	Column: Bench Monkey Cast a skeptical eye over new ideas in chemistry.
Chemistry World March 2011	Microwave chemistry - green or not? Microwave-assisted chemistry might not deserve its environmentally friendly reputation, argues Jonathan Moseley
Chemistry World August 16, 2009 Tom Bond	Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis.
Chemistry World July 9, 2012 Phillip Broadwith	'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom.
Chemistry World April 12, 2012 Simon Hadlington	Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds.
Chemistry World August 2007 Derek Lowe	Opinion: In the Pipeline Process chemists just don't get the credit they deserve.
Chemistry World April 14, 2009 Lewis Brindley	Osmium and pyridine ring together Organic chemists in China have found a way to put osmium into a pyridine ring - leading to the synthesis of the first metallapyridinium complex.
Chemistry World October 2009	Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions
Chemistry World September 2011 Paul Docherty	Column: Totally Synthetic Corey Stephenson of Boston University is an expert a type of reaction called photochemical reduction-oxidation. He has charmed photons into performing many chemical tricks, but one is a photoredox dehalogenation using blue light and a ruthenium bipyridyl catalyst.
Chemistry World June 10, 2010 Simon Hadlington	Elusive intermediate snared Chemists in Germany have succeeded in trapping an elusive intermediate involved in a key synthetic reaction catalysed by an organic molecule.
Chemistry World September 4, 2008 Fred Campbell	Two catalysts better than one US researchers have cracked a long standing problem in chemical synthesis - the catalytic alpha-alkylation of aldehydes - by combining two catalysts in one pot.
Chemistry World November 25, 2014 James Urquhart	Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions.
Chemistry World April 2010 Paul Docherty	Column: Totally Synthetic When one attempts the first synthesis of a natural product, the set of challenges are often unknown; which intermediates are either inaccessible or unstable, for instance.
Chemistry World July 22, 2015 James Morey	Organic synthesis: state of the art -- 2011--2013 This book would be ideal for those needing to be on top of the literature in synthetic organic chemistry, but who don't have the time to read the ever-increasing body of pertinent articles.
Chemistry World November 6, 2008 James Mitchell Crow	Double reactor makes hydrogen and syngas Two chemical reactions key to producing future fuels can be linked together in a single membrane-based reactor to increase their efficiency, say Chinese chemists.
Chemistry World July 30, 2015 Derek Lowe	A precision instrument? How much do medicinal chemists and their biology colleagues really trust each other's data? In the end, they have to, because drug discovery is a team sport.
Chemistry World August 22, 2014 Derek Lowe	Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today.
Chemistry World June 2011	Column: Totally Synthetic I've never heard of the Polonovski-Potier reaction, the keystone of a remarkable synthesis by a team led by Tohru Fukuyama at the University of Tokyo, Japan.
Chemistry World April 25, 2014 Derek Lowe	Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found.
Chemistry World October 2007 Derek Lowe	In the Pipeline One of the biggest areas of chemical research these days is in catalytic processes. It's one of the places we can really improve our processes, especially when you count the waste stream (as you should) as part of the total energy bill.
Chemistry World March 2012	Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug
Chemistry World August 26, 2010 Simon Hadlington	A self-optimising microreactor system Chemists in the US have developed a microreactor system which automatically calculates the optimal conditions for the chemical reaction it is undertaking.
Chemistry World February 2011 Paul Docherty	Column: Totally Synthetic Although most of the natural products I've discussed have had biological activity at the core of the rationale for their synthesis, most organic chemists will admit that an unusual chemical structure is by far the stronger draw.
Chemistry World April 10, 2008 Mark Peplow	'Pot-in-a-Pot' Technique Makes Impossible Cascade Reactions Easy A simple technique that nests a series of reaction vessels could help chemists avoid the tedium and expense of purifying organic compounds after each step of a long synthesis.
Chemistry World July 27, 2009 Simon Hadlington	Peer review by live blogging Blogging can immediately bring together expert opinion on a given topic. Poorly reviewed papers claiming novelty can be expected to be rapidly dissected in the blogosphere, as some chemists have found out.
Chemistry World September 26, 2012 Derek Lowe	Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run?
Chemistry World November 2007 Derek Lowe	Column: In the Pipeline Chemists are finally going with the flow.
Chemistry World June 24, 2012	An Invaluable Resource In the new edition of "Organic Syntheses Based on Name Reactions: A Practical Guide to 750 Transformations," the authors deliver a comprehensive guide to named reactions in organic synthesis.
Chemistry World September 20, 2007 Lewis Brindley	New Catalyst Rings the Changes Organic chemists in the US have developed a method to control the stereochemistry of a useful intramolecular Diels-Alder reaction.
Information Today May 5, 2011 Robert E. Buntrock	SciPlanner: Latest Addition to the CAS Suite of Programs In over a century of existence, Chemical Abstract Service has become the premier source of chemical information.
Chemistry World March 22, 2012 Ross McLaren	Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule.
Chemistry World October 12, 2015 Emma Stoye	Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84.
Chemistry World January 14, 2015 Karl Collins	Alkynes reverse reactivity Coupling together thiols and alkynes -- both inherently nucleophilic species -- is a tricky prospect.
Reactive Reports December 2006 David Bradley	Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database.
Chemistry World March 25, 2011 Simon Hadlington	New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists.
Chemistry World February 11, 2008 Lewis Brindley	Oxidation Goes Green A new 'green' strategy for making useful nitrogen-based chemicals has been announced by chemists in the UK.
Chemistry World May 26, 2015	Catching the runaways I think each cohort of industrial chemists has a runaway industrial reaction that defines their generation.
Chemistry World August 30, 2009 Phillip Broadwith	C-H oxidation proves its worth US researchers are going against the grain of total synthesis and developing new approaches to complex molecules.
Chemistry World August 14, 2014 Elisabeth Ratcliffe	Photoredox route to medically-important heterocycles Researchers in the US have developed a new photo catalyzed coupling reaction that could provide a pathway to a huge number of biologically active compounds.
Chemistry World January 2, 2013 Paul Docherty	Flueggine A One of the most prolific sources of biologically active natural products is traditional medicines -- whose active components can be exceptionally potent. The Euphorbiaceae family of plants is a productive source of medicinal targets, including the Securinega alkaloids.
Chemistry World November 5, 2015 Emma Stoye	Unnatural nanoreactor puts click reaction in the spotlight A protein 'nanoreactor' that can monitor a click chemistry reaction at the level of single molecules has been created by adding an unnatural amino acid to a nanopore.
Chemistry World November 3, 2008 Simon Hadlington	Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple?
Reactive Reports Issue 60 David Bradley	Mark Leach Interview with the owner of Meta-Synthesis, a company aimed to reveal the inner secrets of chemistry to as wide an audience as possible.