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HHMI Bulletin
May 2011
Sarah C. P. Williams |
The Next Statin Although clinicians have firmly established the link between cholesterol levels and heart disease, there are still more questions than answers when it comes to the nitty-gritty molecular details of this connection.   |
Chemistry World
August 27, 2015
Phillip Broadwith |
Drugs in a class of their own In the last month, three drugs in new therapeutic classes have been approved for cardiovascular diseases. |
BusinessWeek
April 19, 2004
Catherine Arnst |
Cholesterol: How Low Should It Be? New studies say as low as possible, but drugs aren't for everybody |
Chemistry World
May 1, 2014
Rowan Frame |
Taking inspiration from green tea Green tea is good for you, but why? Scientists in China are trying to answer one aspect of this huge question by pinpointing which components of green tea help lower cholesterol levels, as well as how they do it. |
Chemistry World
January 27, 2011
Elinor Richards |
Diet affects cholesterol drug Copper and zinc in the diet could impair the action of statin drugs, compounds prescribed to lower cholesterol, say US scientists. |
The Motley Fool
December 23, 2003
Arash Mostaghimi |
The Cholesterol Wars Who will win the fight to save your arteries? Fortunately for our corpulent country, pharmaceutical companies want to unclog our arteries -- and lighten our wallets. But which pharma stock will add to most girth to a portfolio? |
Chemistry World
August 14, 2015
Jessie-May Morgan |
Antioxidant assumptions flipped for garlic thiosulfinates New mechanistic investigations at the interface of chemistry and biology reveal thiosulfinates of garlic and petiveria are not the superstars of the antioxidant world they were once thought to be. |
Scientific American
April 2005
Diane Martindale |
Reactive Reasoning Is an inflammation protein the next cholesterol? |
American Family Physician
December 15, 2000
Alan J. Garber |
Attenuating Cardiovascular Risk Factors in Patients with Type 2 Diabetes All cardiovascular risk factors except smoking are more prevalent in patients with type 2 diabetes. In addition to exercise, weight control, aspirin therapy and blood pressure control, therapy to modify lipid profiles is usually necessary... |
The Motley Fool
December 30, 2003
Arash Mostaghimi |
Turning Cholesterol Into Cash With 62 million Americans suffering from heart disease, it's a huge target for major drug makers. |
The Motley Fool
September 24, 2010
Brian Orelli |
Prepare for This $12 Billion Whoosh Pfizer's Lipitor is the top-selling cholesterol drug -- in fact, it's the top selling drug period -- but it'll start to see generic competition in a little over a year. |
American Family Physician
March 15, 2005
Lockman et al. |
Treatment of Cholesterol Abnormalities The relationship between coronary heart disease and elevated cholesterol levels has been recognized for many years, but now studies show an improvement in patient-oriented outcomes in patients receiving drug therapy. |
BusinessWeek
November 22, 2004
Barrett & Carey |
Wondering About A Wonder Drug While the benefits of statins, sold under names such as Lipitor and Zocor, are well established, some doctors argue that their side effects have not received adequate scrutiny. |
The Motley Fool
August 24, 2011
Brian Orelli |
Can Roche and Merck Succeed Where Pfizer Failed? CETP inhibitors are lucrative but risky. |
American Family Physician
April 15, 2003 |
Cholesterol What is cholesterol?... Why is a high cholesterol level unhealthy?... When should I start having my cholesterol level checked?... Are there different kinds of cholesterol?... What can I do to improve my cholesterol level?... etc. |
BusinessWeek
November 27, 2006
Gene G. Marcial |
ISIS Takes Heart From A Promising Drug ISIS Pharmaceuticals is a name to watch in the lucrative arena of cholesterol reduction. |
American Family Physician
January 15, 2001 |
Goals for Lowering Your Cholesterol Why is it important to have a normal cholesterol level?... What does the term "total cholesterol" mean?... Why is LDL called the "bad" cholesterol?... What are normal cholesterol levels?... How can I reduce my LDL and total cholesterol levels?... etc. |
Chemistry World
September 18, 2015
Rebecca Trager |
Amgen expands cardiovascular portfolio with Dezima acquisition Dezima's lead molecule is the cholesterol-lowering drug TA-8995. |
Science News
June 2, 2007
Janet Raloff |
Tea -- Milking It Adding milk doesn't diminish tea's antioxidant bounty, research finds. |
Managed Care
April 2004
Jack McCain |
Statin Therapy: More Than Meets the Eye? Statin selection has just become more complicated. Will physicians be diverted from interventions that may be less costly and just as effective? |
American Family Physician
January 15, 2002
Lori J. Mosca |
Optimal Management of Cholesterol Levels and the Prevention of Coronary Heart Disease in Women Elevated levels of low-density lipoprotein cholesterol and triglycerides and low levels of high-density lipoprotein cholesterol are significant risk factors for coronary heart disease. Abundant data show inadequate utilization of lipid-lowering therapy in women... |
American Family Physician
October 15, 2006
Sharonne N. Hayes |
Preventing Cardiovascular Disease in Women The American Heart Association guidelines for cardiovascular disease prevention in women provide physicians with a clear plan for assessment and treatment of cardiovascular disease risk and personalization of treatment recommendations. |
Chemistry World
January 19, 2009
Manisha Lalloo |
Synthetic HDL could boost body's 'good cholesterol' US scientists say gold nanoparticle based therapies could be used to help boost levels of good cholesterol in our bodies. |
AskMen.com
Shannon Clark |
Cholesterol Lowering Diets If you want a healthy system, it's worth taking the time to understand cholesterol-lowering diets. |
Nurse Practitioner
February 2012
Wood & Gordon |
Preventing CVD in women: The NP's role This article focuses on the new American Heart Association guidelines for preventing cardiovascular disease in women and the nurse practitioner's role in implementing them. |
The Motley Fool
December 4, 2006
Michael P. Cecil |
Pfizer's Cholesterol-Drug Hopes Crumble In surprising and disappointing news, the pharma's promising new drug fails clinical trials. With Pfizer shares declining because of the bad news, is now a good time to buy? |
Nutrition Action Healthletter
October 2001 |
Read My Lipids How to lower your risk of a heart attack... |
Food Processing
June 2009
Diane Toops |
Superfruits: Back to Basics You don't have to travel to faraway places to get your antioxidants. |
AskMen.com
April 8, 2014
Elizabeth Klodas |
There's A Good Chance You'll Suffer From This Taboo Ailment At Some Point Although many assume that low testosterone, psychological factors or medications are to blame, the truth is that the vast majority of ED is caused by plaque buildup, which is intimately tied to diet. |
Pharmaceutical Executive
May 1, 2006
Sunshine K. Mugrabi |
Back Page: Risk Assessment New thinking and diagnostic tests may change how statins are marketed and prescribed. |
BusinessWeek
March 11, 2010
Ellen Gibson |
The Quest to Boost Good Cholesterol Cleveland Clinic's Steven Nissen is again pursuing a drug that will attack plaque by raising HDL. |
Science News
March 29, 2003
Janet Raloff |
Cranberry Juice -- A Cocktail for the Heart Scientists report that regular consumption of cranberry juice in cocktail form yields cholesterol benefits in middle-age men and women. |
Health
February 2007
Eric Steinmehl |
The Latest Medial Breakthroughs for the Heart Last year's biggest medical advances are changing the face and future of your health. Here's what you need to know - now! |
BusinessWeek
November 24, 2010
Tom Randall |
Merck May Have a Cholesterol Winner Merck told doctors at the American Heart Assn. annual meeting that new data showed its drug anacetrapib had reduced bad cholesterol by 40 percent while raising good cholesterol by an unprecedented 138 percent. |
Pharmaceutical Executive
October 1, 2006
Rob Scott |
Thoughtleader: Life After Lipitor A conversation with a former Pfizer executive who "launched the world's best-selling drug." |
American Family Physician
March 1, 2002
Richard S. Safeer |
Cholesterol Treatment Guidelines Update In addition to modifying current strategies of risk assessment, the new guidelines stress the importance of an aggressive therapeutic approach in the management of hypercholesterolemia... |
American Family Physician
July 15, 2005
Lee Radosh |
STEPS: Colesevelam (WelChol) for Reduction of LDL Cholesterol Colesevelam lowers LDL cholesterol levels a small amount (7% to 16%) when used alone and provides additional cholesterol lowering when added to statin therapy. |
Nutra Solutions
September 1, 2006 |
Sufficiently "Antioxidized" Efficacy of high oxygen radical absorption capacity (ORAC) supplements is an issue, but not for long. |
Science News
October 18, 2003
Janet Raloff |
As If You Needed Another Reason to Eat Strawberries (with recipe) Scientists at Cornell University find that this fragile fruit not only tastes great and contains vitamins but also may offer surprisingly potent benefits in the body's fight against cancer and heart disease. |
Food Processing
December 2012
Heidi Parsons |
New Frontiers for Heart Healthy Ingredients While the key ingredients, such as oat bran and antioxidants, are vital, new ingredients have been gaining ground in the battle to keep our tickers ticking longer and better. |
The Motley Fool
April 2, 2008
Michael P. Cecil |
Irrational Exuberance for Vytorin and Zetia? Drugmakers Merck and Schering-Plough certainly hoped data from the Enhance study would enhance the value and status of their blockbuster cholesterol-fighting drugs Zetia and Vytorin -- but its results did quite the opposite. |
Managed Care
November 2004
Martin Sipkoff |
OTC Status for Low-Dose Lovastatin Would Have Widespread Implications The FDA stands poised to approve OTC low-dose statins, following a similar change in United Kingdom. |
American Family Physician
October 15, 2006 |
Cardiovascular Disease: What You Should Know A patient guide: What is cardiovascular disease?... How can I tell if I have CVD?... What can I do to prevent CVD?... Where can I get more information?... |
The Motley Fool
August 30, 2007
Brian Orelli |
Merck Tries to Stop the Flushing The FDA will review the pharma's new cholesterol drug. The biggest worry with getting CORDAPTIVE approved is probably not with its effectiveness, but with safety. Investors, take note. |
The Motley Fool
November 16, 2009
Brian Orelli |
Abbott Puts a Nail in Merck's Coffin There's a clear winner from the American Heart Association conference. |
Food Processing
October 2009
Toops & Fusaro |
Berries have a Berry Good Year in 2009 Bumper crops lead to lower prices, which lead to more applications of berries in food & beverage products. |
BusinessWeek
July 26, 2004
Amy Barrett |
Hooked On The Cash From Cholesterol Cholesterol-lowering drugs are massive moneyspinners. But can big pharmaceutical companies sidestep expiring patents? |
The Motley Fool
December 16, 2008
Brian Orelli |
Doubling Up on Triple Lipid Drugs The Food and Drug Administration gave Abbott Lab's TriLipix the thumbs-up, approving it for use by itself or with statins. |
American Family Physician
October 15, 2003
Morris & Tiller |
Ezetimibe for Hypercholesterolemia Ezetimibe is safe and effective for lowering LDL cholesterol and triglyceride levels, but has not been shown to affect patient-oriented outcomes. |
Chemistry World
April 2011 |
Column: In the Pipeline If you look over the whole pharmacopeia, you'll see there are a lot of compounds that got their start as natural products. |
