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Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists.   |
Chemistry World
October 21, 2010 |
Mining Soil DNA for Molecular Decorators US Researchers have harnessed enzymes hidden in the genomes of soil bacteria to modify a natural antibiotic molecule in ways that would be difficult or impossible by traditional synthesis. |
Chemistry World
March 30, 2011
Hayley Birch |
Amino acid synthesis hints at how the genetic code expanded The detailed pathway for the biosynthesis of pyrrolysine - the 22nd and latest amino acid to be discovered - has been outlined by US researchers. |
Chemistry World
June 9, 2008
Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
Chemistry World
August 6, 2007
Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Reactive Reports
March 2005
David Bradley |
Microbial Manufacturing A bacterium is a microscopic chemical factory producing antibiotics, immunosuppressants, and anticancer drugs no chemist can synthesize. but pharmaceutical companies have been tapping into microbial drug manufacturing for some time. |
Chemistry World
April 3, 2008
Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Chemistry World
August 2, 2011
Phillip Broadwith |
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids. |
Chemistry World
November 5, 2013
Emma Stoye |
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. |
Chemistry World
December 4, 2009
Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
Chemistry World
September 19, 2008
John Bonner |
Filling the antibiotic gap Resistance to currently available antibacterial drugs is causing growing concern among doctors who find themselves unable to treat common infections |
Chemistry World
March 8, 2007
Simon Hadlington |
Researchers Claim Antibiotic Holy Grail Researchers in Canada have revealed the structure of a key enzyme involved in the synthesis of bacterial cell walls. The finding opens up the possibility of developing new and improved antibiotics and overcoming the increasing problem of bacterial resistance to existing drugs. |
Chemistry World
February 22, 2011
Amaya Camara-Campos |
Repairing faulty genes Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. |
American Family Physician
January 15, 2004 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics work against all infections?... What is "antibiotic resistance"?... Why should I worry about antibiotic resistance?... How do I know when I need antibiotics?... How should I take the antibiotics that my doctor prescribes?... etc. |
Chemistry World
December 20, 2011
Laura Howes |
Cutting edge chemistry in 2011 With the help of an expert panel of journal editors Chemistry World reviews the ground breaking research and important trends in this year's crop of chemical science papers. |
AskMen.com
Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Chemistry World
September 12, 2006
Mark Peplow |
Bacteria Silenced by Conversation Stoppers Molecules that interrupt the chemical conversations of bacterial communities are showing early promise in beating the bugs. |
Chemistry World
February 22, 2010
Hayley Birch |
Soil switches on antibiotic genes in bacteria So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown. |
American Family Physician
September 15, 2006 |
When Antibiotics Can Help A consumer's guide: What are antibiotics?... How do antibiotics work?... What is antibiotic resistance?... How can I prevent antibiotic resistance?... |
American Family Physician
March 15, 2001 |
Avoiding Resistance to Antibiotics-- When Do I Need an Antibiotic? When bacteria are exposed to the same antibiotics, after a while the antibiotic can't fight the germs anymore... |
Chemistry World
June 14, 2006
Simon Hadlington |
Natural Metabolism of Fluorine Scientists have isolated a cluster of bacterial genes responsible for the biochemical processing of fluorine. The research follows the discovery of a unique enzyme that incorporates inorganic fluoride into organic metabolites. |
Chemistry World
May 6, 2014
Andy Extance |
WHO raises alarm on deadly bacteria The World Health Organization has warned antibiotic resistant bacteria could bring a nightmarish future, where seemingly trivial scrapes turn lethal, and currently routine operations become too risky to contemplate. |
Reactive Reports
Apr/May 2005
David Bradley |
At Last, the Structure of DNA Researchers have made a significant advance in our understanding of life's main molecule, using X-ray crystallography to determine the three-dimensional structures of nearly all the possible sequences of a macromolecule. |
Nutrition Action Healthletter
May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
American Family Physician
December 15, 2000 |
Antibiotics: When They Can and Can't Help Antibiotics are strong medicines that can stop some infections and save lives. When they aren't used the right way, antibiotics can cause more harm than good. You can protect yourself and your family by knowing when you should use antibiotics and when you should avoid them... |
IEEE Spectrum
March 2011
Lucks & Arkin |
Synthetic Biology's Hunt for the Genetic Transistor How genetic circuits will unlock the true potential of bioengineering |
Science News
June 28, 2003
Ben Harder |
McDonald's Cutback in Antibiotics Use Could Reduce Drug-Resistant Bacteria The fast-food chain McDonald's announced on June 19 that it will stop its farms under contract from feeding chicken, cattle, and pigs certain antibiotics intended to accelerate the animals' growth. That step might slow or reverse the rise of antibiotic-resistant bacteria that can infect people. |
American Family Physician
October 1, 2006 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics always work?... What is bacterial resistance?... What can I do to help myself?... etc. |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
Salon.com
December 19, 2000
Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
Bio-IT World
February 10, 2003
Malorye Branca |
Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic. |
Chemistry World
August 25, 2010
Phillip Broadwith |
Antibiotic nanoparticles go for gold Chemists in the UK and India have developed a simple, one step synthesis of gold nanoparticles incorporating an antibiotic, without using any other chemicals. |
Chemistry World
August 13, 2007
Simon Hadlington |
Nature Captured in a Test-Tube Two groups of researchers have demonstrated how a complex chain of reactions catalyzed by multiple enzymes can be reconstructed in the test tube to synthesize naturally occurring products that have potential therapeutic properties. |
Fast Company
May 2009
Elizabeth Svoboda |
Biotechs Wage War on Superbugs With antibiotic resistance on the rise, three biotechs are developing new ways to wage war on superbugs. |
Chemistry World
April 4, 2007
John Bonner |
Antibiotic Combinations Tackle Resistance Using combinations of certain antimicrobial compounds can favor the growth of non-resistant strains of bacteria at the expense of resistant ones. The surprising finding may provide a general strategy to help eradicate strains of bacteria that are resistant to antibiotic therapy. |
Chemistry World
June 10, 2009
James Urquhart |
Enzyme employs unusual cleavage reaction The mechanism of an unusual carbon bond cleavage reaction in the biosynthetic pathway of phosphinothricin tripeptide (PTT) - a naturally occurring herbicide and antibiotic compound - has been elucidated by US scientists |
Chemistry World
September 24, 2015
Harriet Brewerton |
Antibiotics pit against bacterial biofilms Scientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics. |
Chemistry World
April 4, 2011
Carol Stanier |
Mighty micelles that make themselves Scientists in the US and Singapore have made self assembling micelles of cationic polymers that kill bacteria but are biodegradable - raising further hope of a nanotechnology solution to the problem of antibiotic resistance. |
Chemistry World
April 27, 2011
Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
American Family Physician
October 1, 2004 |
Antibiotics: When They Can and Can't Help An overview on how antibiotic therapy comes into play in the treatment of the flu and colds. |
Popular Mechanics
April 15, 2009
Erin McCarthy |
Is Fringe's Genetic Monster Possible? Unlike the monster on Fringe, altered animals typically have only a single gene difference from non-altered animals -- but they can look different. |
Chemistry World
February 15, 2011
Mary Badcock |
Building up a natural product toolkit US scientists have come up with a method that makes it easier to extract compounds that are difficult to isolate from crude natural product mixtures. |
Bio-IT World
January 21, 2005
Mark D. Uehling |
How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis. |
Scientific American
May 2009
Melinda Wenner |
Quiet Bacteria and Antibiotic Resistance Bacteria devoted to growth instead of "quorum sensing" communication could beat antibiotic resistance. |
Chemistry World
July 15, 2010
Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Chemistry World
August 26, 2007
Michael Gross |
Grapevine Genome Reveals Wine's Flavour Secrets The genome of the grapevine, Vitis vinifera, has been decoded by scientists. The research reveals the genetic origins of certain aromas and health-promoting compounds in wine. |
Pharmaceutical Executive
July 30, 2007
Sarah Houlton |
Global Report: Make Resistance Futile Patients are losing the battle against bacteria. Can pharma be convinced to swing the sword of new antibiotic development? |
Scientific American
June 2009
Melinda Wenner |
Genetic Copy Variations and Disease A new sense for how variable numbers of genes cause disease. |
