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Chemistry World December 6, 2006 Jessica Ebert |
Structure of Key Influenza A Protein Revealed The crystal structure of a molecule important for the replication of the influenza A virus has been solved. Now that scientists know what the protein looks like they can design drugs that block its action and prevent viral spread through the body. |
Chemistry World August 3, 2009 Simon Hadlington |
Computational chemistry predicts flu mutations Researchers in the US have shown how it might be possible to use computational chemistry to predict which mutations in a key influenza virus protein could lead to dangerous new strains of the disease. |
Chemistry World January 22, 2013 Andrew Turley |
Flu vaccine without the eggs approved Flublok from US biotech Protein Sciences has become the first flu vaccine made using an insect virus to win marketing approval in the US. |
Chemistry World July 6, 2007 Michael Gross |
Predicting How Proteins Fold Researchers in Italy and the UK have now developed a computational approach that can simulate the folding of membrane proteins in atomic detail. |
Chemistry World February 2007 Philip Ball |
The Crucible Molecular biology isn't just about the cleverness of proteins and nucleic acids. Even the molecules often assumed to be just part of the scaffolding, such as lipids, and the very water that bathes them all, may have inventive roles to play. |
Chemistry World September 1, 2008 James Mitchell Crow |
Drug discovery on a chip Scientists in the US have, for the first time, used microfluidics to discover drug leads. The team's lab-on-a-chip device revealed inhibitors of a key membrane-bound protein in hepatitis C virus |
BusinessWeek September 12, 2005 John Carey |
A Better Way To Ambush AIDS? HIV increasingly outwits today's drugs even as side effects take a toll. But Panacos Pharmaceuticals' experimental drug opens the door to a new line of attack. |
Chemistry World April 8, 2010 Simon Hadlington |
Arsenic anticancer target revealed Researchers from China and France believe they have uncovered the molecular mechanism by which arsenic trioxide kills certain cancer cells. |
Managed Care February 2005 Jack McCain |
Managed Care (and Everyone Else) Unprepared for the Next Killer Flu Could avian flu give rise to a pandemic that might rival the fearsome Spanish flu? Is the nation ready? Health plans may be called upon to administer vaccinations and identify high-risk patients, but what about he millions of Americans who lack health insurance? |
Chemistry World February 7, 2006 Jon Evans |
Plant-Derived Drug Approved in US Dow AgroSciences has become the first biotech firm to gain US regulatory approval for a plant-derived drug. The company claims it will be able to manufacture many other vaccines, for animal and human diseases, using its plant-based production technology. |
BusinessWeek November 24, 2003 John Carey |
Barring The Door Against AIDS A new generation of drugs focuses on keeping the virus from entering cells. |
Popular Mechanics March 2006 Jeff Wise |
Fighting Fire With Fire By recreating an extinct virus that killed as many as 50 million people, scientists race to defeat avian flu before it evolves into a deadlier form. |
Chemistry World May 29, 2013 Hayley Birch |
Fast flu mapping without the sequencing Australian researchers showed that using data from flu virus proteins produced similar trees to those generated by genetic sequencing, suggesting a rapid-fire solution for identifying viruses during outbreaks. |
Chemistry World January 5, 2007 Victoria Gill |
PEG Makes Cheaper Drugs for Developing Countries UK and Indian scientists have embarked on a collaboration to develop a new protein-based treatment for hepatitis C, which they say will provide an affordable drug urgently needed in countries where resources are limited. |
HHMI Bulletin Winter 2013 Megan Scudellari |
Tunneling Out A research team including HHMI investigator Melissa Moore at the University of Massachusetts Medical School has discovered an alternative passageway used by RNA -- protein complexes to exit the nucleus. |
Chemistry World January 19, 2011 Jon Cartwright |
Modified protein binders give shortcut to drugs The method, which involves attaching polypeptides to the binders, could help reduce the work required to develop protein binders into safer drugs. |
Chemistry World November 11, 2011 Phillip Robinson |
Functionalized fiber catches flu before you do Scientists in China have developed a fibre that can trap the flu virus, which could be used in face masks and air filters to help to control the spread of the disease. |
Chemistry World December 5, 2007 Ananyo Bhattacharya |
Structural Snapshot Shows Monster Protein A structural snapshot of a protein capsule has revealed details of the largest cellular component ever imaged by x-ray crystallography. |
Chemistry World November 25, 2009 Simon Hadlington |
Virus shells traps multiple proteins Scientists in The Netherlands have devised a way to pack large numbers of proteins into the empty shell of a virus. |
Chemistry World October 25, 2007 |
Elusive Drug Target Finally Seen Scientists have captured an atomic-scale picture of a receptor protein from a family that is the target of thousands of drugs. |
Chemistry World October 1, 2014 Michael Gross |
Viruses melt 'glassy' DNA US Researchers have identified the factors that enable viral DNA to turn from solid to liquid, which allows them to infect host cells. They say the process could become a target for new antiviral therapies. |
BusinessWeek February 9, 2004 Catherine Arnst |
What You Need To Know About Avian Flu The current avian flu outbreak in Asia is the fifth since 1997 to infect humans. This has raised a red flag for infectious disease experts, who fear the strain could mutate and spark a devastating flu pandemic. |
Chemistry World September 25, 2009 Simon Hadlington |
New MRI protein probe Researchers in Japan have invented a new way to detect the presence of proteins in cells and tissues by magnetic resonance imaging. |
Chemistry World August 26, 2014 Andy Extance |
No-frills coats set a trend for designer viruses Dutch scientists have built a simple model of viruses' protective coats in an attempt to create viral mimics that could fight diseases, as opposed to causing them. |
Scientific American July 3, 2006 Jeneen Interlandi |
An Immune Portal Protein may be a key to autoimmune disorders |
Chemistry World October 31, 2010 Michael Gross |
Kiss of death for cancer cells Scientists have deciphered the surprising structure of the perforin pore, which delivers the 'kiss of death' to virus-infected cells and cancer cells in the body. |
Chemistry World September 24, 2007 Simon Hadlington |
Viral Nanoreactor Captures Single Molecules Researchers in the Netherlands have created a biochemical nanoreactor by cracking open a virus, removing its contents then reassembling the virus's protein coat around a single molecule of enzyme. |
AskMen.com Jacob Franek |
Avian Influenza 101 Here is everything you need to now about avian influenza so that you can better protect yourself. |
Chemistry World January 10, 2008 Simon Hadlington |
Proton Joins Elite Club of Cellular Messengers Researchers have discovered a new chemical that carries messages rapidly between cells - the first for more than 20 years. But unlike conventional signalling molecules, this is a far simpler chemical entity: it is the humble proton. |
HHMI Bulletin February 2011 Michele Solis |
Right Before Your Eyes Coupling protein sequence to function, thousands of variants at a time. |
Bio-IT World November 2005 |
News Blast Applied Biosystems contributes 400,000 primers... Researchers have discovered the full genetic sequence of many different strains of the flu... Sigma-Aldrich launches Panorama Human Cancer Version 1 Protein Functional Microarray... |
Bio-IT World October 10, 2003 Jeffrey Skolnick |
Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways. |
Chemistry World June 1, 2014 Tim Wogan |
Squid skin conductor for bioelectronics A protein from squid skin is a good conductor of protons, researchers in California have discovered. |
Chemistry World November 5, 2015 Emma Stoye |
Unnatural nanoreactor puts click reaction in the spotlight A protein 'nanoreactor' that can monitor a click chemistry reaction at the level of single molecules has been created by adding an unnatural amino acid to a nanopore. |
Chemistry World February 3, 2013 Andy Extance |
Enzyme draws nanopore protein sequencing nearer US scientists at the University of California, Santa Cruz, have made a key step towards nanopore protein sequencing, thanks to an 'unfoldase' enzyme. Mark Akeson's team exploited this enzyme to unravel proteins and pull them through nanopores. |
HHMI Bulletin February 2011 Sarah C.P. Williams |
Enforcing Order Changing the spatial arrangement of molecules in a cell can alter their functions. |
Chemistry World June 2, 2006 Jon Evans |
Axons Get Directions Scientists are a step closer to understanding the processes that control the growth and spread of nerve cells, following the discovery of a protein complex that directs the transport of building material to growing axons. |
HHMI Bulletin Winter 2013 Nicole Kresge |
A Structural Revolution Over the years, scientists and artists have used an assortment of techniques to showcase molecular structure. |
HHMI Bulletin May 2012 Nicole Kresge |
Locating a Genetic Glitch A team of 41 scientists led by HHMI investigator Louis Ptacek has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known protein that may be responsible for communication between neurons. |
Chemistry World April 16, 2009 Simon Hadlington |
Mass spec pinpoints flu virus types Researchers in Australia have shown that exquisitely accurate mass spectrometry can be used to distinguish between different sub-types of the influenza virus |
Chemistry World November 27, 2013 Jennifer Newton |
A cytochrome from scratch Artificial proteins could be closer to participating in natural biochemical pathways after researchers show that bacteria will process amino acid sequences entirely unrelated to any natural protein to produce a fully functioning cytochrome. |
Reactive Reports Issue 51 David Bradley |
Protein Crystals Trapped Researchers have developed a new technique for crystallizing proteins, which could open up a whole range of materials to this powerful analytical technique. |
Chemistry World June 14, 2011 |
A New Spin on Protein NMR A new technique will allow researchers to study protein structure in greater detail using NMR. |
Reactive Reports September 2005 David Bradley |
When Good Turns Bad Prions, the protein-like pathogens at the heart of the fatal brain disorder CJD, so-called mad cow disease, and related diseases can rapidly "remodel" good proteins into bad, according to US scientists, who have demonstrated this for the first time in living cells. |
Chemistry World September 29, 2010 Hayley Birch |
Protein folding: knotted or not A new study may help scientists unravel the complex problem of protein folding. The study suggests knotted proteins, which present a particular challenge to folding experts, could be untied with a couple of well-targeted tugs. |
Chemistry World August 2, 2012 Philip Ball |
Polymer replacement for the hydration shell The sheath of water molecules, called a hydration shell, that gives protein molecules the flexibility to do their catalytic job can be replaced by polymers, according to Adam Perriman of the University of Bristol and his coworkers. |
Chemistry World April 26, 2009 Simon Hadlington |
Glowing protein in 'animal photosynthesis' Scientists have discovered that a glowing protein found in some exotic marine animals and used widely as a 'marker' in molecular biology has another remarkable property |
The Motley Fool August 4, 2004 Charly Travers |
Labs' Report Offers Mixed Results TProtein Design Labs' royalty intake looks great, but its drug development does not. |
Chemistry World February 2, 2014 Emma Stoye |
Artificial membrane harvests light like a cell Photosensitive compounds built into an artificial membrane can capture light energy in the same way as proton pumps found in biological cells. |
Chemistry World June 13, 2011 Laura Howes |
Cells turned into living lasers with fluorescent protein With a little help from a fluorescent protein, mammalian cells have been transformed into living lasers. This discovery could help improve imaging of living cells, enabling researchers to explore what's going on inside. |