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HHMI Bulletin
Winter 2013
Sarah C.P. Williams |
Cellular Search Engine Craig Mello's lab has now uncovered the reason piRNA molecules are so ubiquitous and exist in so many forms in C. elegans: so they can pair with essentially any genetic sequence they encounter during their endless scanning.   |
Wired
November 2003
Jennifer Kahn |
Regrow Your Own Broken heart? No problem. New liver? Coming right up. The road to regeneration starts here. |
Smithsonian
June 2006
Amy Crawford |
Interview: Christiane Nusslein-Volhard A Nobel laureate holds forth on flies, genes and women in science. Her first book, Coming to Life, explains the genetic and cellular basis of animal development and explores the ethical implications of recent progress in genomics and biotechnology. |
Scientific American
September 2008
Melinda Wenner |
Rethinking the Wrinkling: Key Genes Cause Aging Key genes, rather than cell and DNA damage, as causes of aging. |
Popular Mechanics
April 15, 2009
Erin McCarthy |
Is Fringe's Genetic Monster Possible? Unlike the monster on Fringe, altered animals typically have only a single gene difference from non-altered animals -- but they can look different. |
Scientific American
November 2008
Christine Soares |
Contest Inspires Limb Regeneration Research Genome-sequencing contest renews regeneration research. |
Salon.com
June 27, 2000
Tabitha M. Powledge |
Book of life? Hosanna! The Human Genome Project has been completed. We will now cure diseases, weed out defective genes and create a new supergeneration in the near future. Not. |
Bio-IT World
December 15, 2004
Nancy Weil |
Running Interference The revolution in RNA interference has galvanized basic research. Now, some biopharmas are pushing the technology from the laboratory to the clinic. |
Reason
Aug/Sep 2000
Ronald Bailey |
Strands of Life Book Review: Genome: The Autobiography of a Species in 23 Chapters, by Matt Ridley |
HHMI Bulletin
May 2012
Nicole Kresge |
Better Than a Straitjacket Scientist Sandhya P. Koushika devised an inexpensive, simple way to get the worms to pause so she can image cellular activity in the transparent creatures. |
Chemistry World
April 2010 |
Column: The crucible We are getting better at manipulating cells to grow into the tissues we need. Chemical factors are key, says Philip Ball |
Bio-IT World
April 15, 2003
Malorye Branca |
Beyond the Blueprint How will the wealth of data emanating from the human genome and allied technologies impact research on health and disease? |
Bio-IT World
December 15, 2003
Zachary Zimmerman |
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. |
Bio-IT World
July 15, 2003
Malorye Branca |
Silence Is Golden RNA interference's scientific, therapeutic, and economic potential is unquestionable, but some sticky questions still remain. |
Chemistry World
October 2, 2006
Bea Perks |
RNAi Pioneers Win Nobel Prize for Medicine Molecular biologists Andrew Fire and Craig Mello have been awarded this year's Nobel prize in physiology or medicine for their discovery of RNA interference. |
Chemistry World
October 31, 2007
John Bonner |
Brain's Wiring Seen in Technicolor Researchers in the US have developed a technique that could allow neurologists to draw a detailed wiring plan of the mammalian brain by inserting genes coding for fluorescent proteins into transgenic mice. |
Chemistry World
November 5, 2007
Lewis Brindley |
Silencing the Pests Two teams of scientists have uncovered a new way to protect crops from two serious insect pests. The teams made use of a process called RNA interference to silence critical genes in the bodies of the insect larvae and stopped them growing. |
Bio-IT World
December 15, 2004
William Marshall |
Applications of RNAi RNA interference is a highly coordinated gene regulatory mechanism that appears to be highly conserved across all metazoans studied thus far. |
Chemistry World
April 28, 2008
Victoria Gill |
Gene silencing gets fat A team of researchers in the US has developed fat-like nanoparticles that can carry fragments of RNA into cells, bring treatments based on gene silencing a step closer. |
BusinessWeek
May 24, 2004
Arlene Weintraub |
Repairing The Engines Of Life Can research into stem cells and other advanced techniques heal ailing hearts and brains? U.S. labs are hamstrung by the federal government. |
Fast Company
November 2009
David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Reason
October 2000
Frederick K. Goodwin & Adrian R. Morrison |
Science and Self-Doubt Why animal researchers must remember that human beings are special... |
Salon.com
May 1, 2000
Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Popular Mechanics
October 2000 |
Science: Greatest Unsolved Mysteries Is there a Fountain of Youth? Will we cure cancer? Can we achieve immortality? Can we create artificial life? Where is the soul? Is the speed of light the ultimate speed limit? Is there other intelligent life in the universe? Can we travel through time? |
Bio-IT World
March 8, 2005
Kevin Davies |
Evolution of New Genes Studied EMBL researchers use comparative genomic analysis to identify new primate-specific gene family. |
Chemistry World
June 9, 2008
Simon Hadlington |
Artificial virus silences genes Scientists in Korea have created an artificial virus that can target the nucleus of cancer cells and knock out specific genes. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
Maternal and Paternal Genes Don't Always Have The Same Effect On Offspring The genes you inherited from your mom and those passed along from your dad don't have equal footing when it comes to how they influence your biology. |
Salon.com
February 13, 2001
Arthur Allen |
Size doesn't matter As scientists unveil the human genome findings, it turns out we have a lot fewer genes than we'd thought, and not many more than a fruit fly... |
Bio-IT World
December 15, 2004
Zachary Zimmerman |
Silence Is Golden Life Science Insights believes that RNAi therapeutics will dramatically affect the pharmaceutical and healthcare industries, becoming the next major class of therapeutics, joining small molecules, proteins, and monoclonal antibodies. |
Bio-IT World
December 15, 2004
David A. Bumcrot |
Identifying RNAi Drug Candidates Breakthroughs in understanding RNA's extensive role in essential cellular processes have opened up the potential for a whole new class of drugs based on RNAi. |
Chemistry World
October 12, 2006
Jessica Ebert |
Reducing the Number of Genes Needed for Life Two of the smallest bacterial genomes sequenced to date provide new clues to the minimum number of genes required to support cellular life. |
Bio-IT World
May 2006
Kevin Davies |
Interpreting Genes and Genomes From microarrays to sequencing technology, molecular diagnostics to the interactome, this year's Bio-IT World Conference showcased exciting advances in genome technology applications, in which software analysis and data management play critical roles. |
Science News
September 10, 2005 |
From the September 7, 1935, issue Not "stuffed"... Capsule before breakfast gives immunity to colds... Genes have double function: Vital as well as hereditary... |
AskMen.com
October 30, 2013
Michelle Magnan |
The Difference Between Usain Bolt And You: The point that David Epstein explores at length in The Sports Gene, is that no two people respond to sports training the same way, because no two genomes are the same. |
Bio-IT World
September 11, 2003
Kevin Davies |
Chipping Away at Cancer In Vivo, In Situ Two studies probe new applications of DNA microarrays, revealing new insights into the pathogenesis and pharmacogenomics of cancer. |
Bio-IT World
November 2005
Nancy Weil |
Dharmacon, Institutes Form siRNA Global Initiative The company has formed a global alliance with leading biomedical research centers aimed at speeding scientific and medical discoveries now that the first complete siRNA (small interfering RNA) library is available for targeting genes in the human genome. |
BusinessWeek
May 24, 2004
Arlene Weintraub |
The Geniuses Of Regeneration The Defense Advanced Research Projects Agency (DARPA) is now considering handing out research grants to scientists working on regeneration, in the hope that someone will turn this dream into reality. |
Bio-IT World
January 21, 2005
Kevin Davies |
Allen Brain Institute Debuts 'Google for Gene Activity' The Allen Institute for Brain Science has released its first set of gene-expression data in the brain for nearly 2,000 mouse genes. The data will have important relevance for the study of brain function, disease, and the role of genes in governing human behavior. |
BusinessWeek
February 26, 2007
Gene G. Marcial |
CytRx Can 'Silence' Genes That Cause Disease Since October, shares of CytRx have more than doubled as investors zeroed in on its RNA interference technology that targets diabetes, obesity, and ALS. |
Fast Company
March 2006
Ramez Naam |
The Body: Bulletproof Gene therapy is on its way - and it's coming fast. |
Managed Care
August 2007
Thomas Morrow |
Gene Expression Microarray Improves Prediction of Breast Cancer Outcomes Flash-frozen samples of surgically removed breast cancer tissue are the key to measuring a patient's risk of metastasis. |
Bio-IT World
February 18, 2004 |
The Quest for Complex Genes Genetic sleuths are homing in on genes for complex diseases with the help of new, and some not so new, tools and strategies. |
