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Chemistry World
August 26, 2008 |
Photonic crystal drug detective A new high-throughput screening system based on photonic crystals could quickly and cheaply detect molecules that disrupt binding between proteins and DNA.   |
Chemistry World
December 4, 2009
Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Technology Research News
March 23, 2005 |
Nanowires track molecular activity Researchers from Harvard University have found a way to use transistors made from silicon nanowires to gain information about how small molecules bind to proteins. |
National Defense
October 2007
Grace Jean |
Building Miniature `Noses' to Sniff Explosives To sense malicious chemicals and substances, such as explosives, scientists are searching for the holy grail in chemical sensing -- a mechanical device that is as good as or better than a dog's nose and can run nonstop to provide continuous monitoring of an environment. |
Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
Chemistry World
April 27, 2011
Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
Chemistry World
December 15, 2015
Michaela Muehlberg |
Bacterial identification gets a culture shock Scientists in the UK have developed a new tool to distinguish bacterial strains from each other. |
Chemistry World
February 11, 2011
Leanne Marle |
Fighting back against antibiotic resistant bacteria Scientists in Japan have revealed how vancomycin dimers are effective against vancomycin-resistant bacteria. |
Technology Research News
September 10, 2003 |
Gold speck highlights molecules How do you sense what is happening at the scale of molecules? Researchers have found a way to detect the very small spectral shifts that occur when the light scattering off a single gold nanoparticle interacts with molecules. |
HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections. |
Chemistry World
June 17, 2014
Simon Hadlington |
Synthetic receptor recognizes entire drug family A team at the University of Brescia has developed a sensor which responds to the portion of the methamphetamine molecule that is common to the entire family. |
Chemistry World
March 6, 2011
Mike Brown |
Molecules that walk, hop and jump 'Two legged' molecules walk, hop and fly across a receptor surface, according to researchers in the Netherlands and Ireland. The findings could help us understand how viruses and bacteria interact with cell membranes, they say. |
Chemistry World
June 23, 2015
Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example. |
Chemistry World
May 29, 2014
Carla Pegoraro |
Dual warhead kills and disarms bacteria A compound that kills bacteria and cleaves their DNA to prevent them passing on drug-resistant genes has been designed by researchers in India. |
Chemistry World
August 6, 2007
Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
Chemistry World
July 15, 2010
Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
Chemistry World
January 29, 2007
Tom Westgate |
Nanocantilever Sets New Mass Detection Record Scientists have built a device capable of detecting masses as small as 1 attogram (1 x 10 -18 g) at ambient temperature and pressure. This sets a new record for detection under these conditions, they claim. |
Chemistry World
February 18, 2011
Carol Stanier |
Speed dating for pharmaceuticals A simple analysis of hydrogen bond strengths finds the best crystallisation partners for drugs, say UK scientists. |
AskMen.com
Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Chemistry World
March 8, 2013
Simon Hadlington |
Battleground develops over antibiotic killing mechanism Two recent papers will require many in the field to re-examine and re-open the question of whether or not several different classes of bactericidal antibiotics do or do not work through a common mechanism. |
Chemistry World
March 4, 2015
Philip Ball |
Program ready to weed out tough drug leads A method for reliably predicting how well a candidate drug molecule will bind to its target receptor would allow libraries of molecules to be screened on the computer, without having to synthesize them all. |
| Industrial Physicist |
Biomimetic Nanotechnology Although biomimetic nanotechnology is in its infancy, with no applications yet reaching commercialization, the barriers in some cases lie mainly in scaling up production processes to industrial levels. |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
Chemistry World
February 6, 2013
Harriet Brewerton |
Diagnosing bacterial growth Antibiotics are used regularly for treating bacterial infections, but there is currently no quick and simple test to determine the most effective type or dose of antibiotic for a specific patient infection. |
Chemistry World
December 2007
Derek Lowe |
Column: In the Pipeline The challenge of biologics. |
Chemistry World
August 11, 2011
Hayley Birch |
'Dial a Molecule' Approach Controls Antibiotic Production Scientists have used genetic methods to control the chemical structures of pacidamycin antibiotics produced in bacteria. Their approach allows them to 'dial into' particular molecules, and to generate new pacidamycins. |
Chemistry World
March 13, 2013
Ned Stafford |
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. |
Chemistry World
October 8, 2013
David Bradley |
3D printing bacteria Jason Shear and colleagues at the University of Texas, US, have developed a 3D printing technique that lets them 'construct' defined bacterial communities so that short-range chemical communications and physical interactions between bacteria can be investigated more systematically than ever before. |
Chemistry World
June 1, 2010
Simon Hadlington |
Structural order gained over conducting polymer Scientists in Canada and the US have shown how it is possible to assemble ordered arrays of short chains of a commercially important conducting polymer on a metal surface. |
Chemistry World
May 12, 2011
Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
Chemistry World
January 30, 2015
Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Chemistry World
April 25, 2007
Victoria Gill |
Nanoscale Scales Scientists at MIT have designed a device able to accurately weigh single nanoparticles within a liquid. The new technique is based on the ultra-sensitive mass detection made possible by nanomechanical resonators. |
Chemistry World
March 6, 2013
Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World
July 8, 2014
Anthony King |
Call for new models to pay for antibiotics Governments will need to think seriously about changing the way they pay for the drugs. That's the conclusion of a report from the UK House of Commons science and technology committee. |
