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Bio-IT World April 16, 2004 |
Portraits in Proteomics Advances in identifying protein biomarkers are spurring new hope in cancer diagnostics, expediting detection and easing testing. |
Chemistry World February 23, 2007 Michael Gross |
X Labelling Springs a Surprise In stark contrast to expectations, researchers have found that the active versions of genes on X chromosomes are more heavily methylated than the inactive versions. |
Bio-IT World Jul/Aug 2006 Deb Janssen |
Managing the Microarray Data Mountain Genomic studies often involve thousands of samples and require hundreds of thousands of assays per sample. Microarray manufacturers are scurrying to satisfy researcher demands for increased array density, sample number, and content flexibility. |
Chemistry World July 2010 Anna Lewcock |
Medicine made to measure Healthcare tailored to suit the genetic makeup of the patient is finally coming to fruition. |
Bio-IT World September 2006 Robert M. Frederickson |
Assays and Knowledgebases for Genomic Analysis An important aspect of any genomic analysis -- whether expression profiling or analysis of DNA-binding elements as above -- is the integration of the data with existing knowledge. |
Salon.com May 1, 2000 Arthur Allen |
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. |
Chemistry World August 19, 2009 Hayley Birch |
Gold nanoparticles detect cancer Chinese scientists have used gold nanoparticles as ultrasensitive fluorescent probes to detect cancer biomarkers in human blood. |
Wired August 2003 Jennifer Kahn |
The End of Cancer (As we Know it) Diagnosis. Chemotherapy. Radiation. Slow painful death. No more. A new era of cancer treatment is dawning. Meet three scientists who are using the revelations of the Human Genome Project to reshape medicine. |
Chemistry World May 2008 Philip Ball i |
Pulling our strings There is much more to DNA than that elegant double helix. The author explores the twists and tangles of chromatin. |
Bio-IT World August 13, 2003 Malorye Branca |
Targeting Tumors Next-generation cancer drugs will take aim with unprecedented certainty, but making them requires a new discovery and development paradigm. |
Fast Company November 2009 David H. Freedman |
The Gene Bubble: Why We Still Aren't Disease-Free When the human genome was first sequenced nearly a decade ago, the world lit up with talk about how new gene-specific drugs would help us cheat death. Well, the verdict is in: Keep eating those greens. |
Pharmaceutical Executive September 1, 2005 Mattingly & Saxberg |
Biomarkers Come of Age In the past five years, biomarkers have become an essential part of pharmaceutical R&D. Seven industry experts explain how it happened - and what comes next. |
Chemistry World January 30, 2014 Anthony King |
Unnatural DNA links click for faster synthesis Human cells can still read strands of DNA correctly if they are stitched together using linkers not found in nature, a new study shows. |
Salon.com December 19, 2000 Carolyn McConnell |
"The Century of the Gene" by Evelyn Fox Keller A new book argues that there may be no such thing as a gene. At least, it has proved very difficult to isolate a discrete physical item that can do the work our notion of the gene does... |
Chemistry World March 1, 2011 Catherine Bacon |
Unravelling chromosomes Danish scientists have used a micro device to isolate centimetre-long portions of human DNA to help study the genetic make-up of diseased cells. |
Chemistry World January 2012 |
DNA motors on With the relentless rise of DNA nanotechnology's popularity, Emma Davies explores the role chemistry has played in its success |
Chemistry World October 25, 2011 Jon Evans |
Carbon nanotubes detect DNA 'flipping out' US chemists have developed a way to detect the chemical modification of a single strand of DNA, by hooking it up to a pair of carbon nanotubes. |
Managed Care February 2008 Thomas Morrow |
As the Use of Biomarkers Grows, Managed Care Companies Will Face Tough Decisions About Setting Limits Health care faces difficult challenges as it increasingly incorporates a personalized approach that uses various biomarkers to influence medical decision-making. |
HHMI Bulletin Spring 2013 Sarah C.P. Williams |
Sounding the Alarm Details on how cells detect and respond to foreign DNA may provide clues to autoimmune diseases. |
Bio-IT World July 2005 Johan Bostrom |
Affymetrix to Acquire ParAllele The companies have been working together for the past two years, with Affymetrix using ParAllele's assay technology with the Affymetrix GeneChip technology. Affymetrix expects to strengthen its assay R&D capabilities and add knowledge in specific assay capabilities through the acquisition. |
Bio-IT World October 14, 2004 Robert M. Frederickson |
Nanosphere Strikes Gold Recently, scientists at Nanosphere developed a colorimetric method for DNA detection that obviates the need for target or signal amplification. |
Chemistry World May 21, 2012 Simon Hadlington |
Rewritable DNA for digital data storage A rewritable memory storage module can form the basis of a digital memory system, scientists suggest, with the cell being able to 'record' transient changes in its internal chemistry. |
Chemistry World October 19, 2015 Matthew Gunther |
The house that DNA built The 2015 chemistry Nobel prize was awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA repair. |
Technology Research News July 30, 2003 Eric Smalley |
Chip senses trace DNA Handheld detectors could one day allow you to monitor your body for cancer, your water for chemicals, and your food for bacteria. This requires inexpensive electronics that are capable of detecting trace amounts of substances. One candidate is a chip containing DNA-tipped carbon nanotubes. |
Chemistry World October 31, 2008 Manisha Lalloo |
DNA-rewinding protein discovered US scientists have found an enzyme that rewinds sections of DNA whose strands have mistakenly come apart. |
Chemistry World November 16, 2006 Simon Hadlington |
Gene-Reading Enzyme Catapulted by Scrunch Power Two teams of researchers have solved a conundrum that has baffled molecular biologists for 20 years -- how the enzyme responsible for `reading' genes can release itself from the portion of DNA to which it initially binds extremely tightly. |
Technology Research News May 5, 2004 Kimberly Patch |
DNA Bot Targets Cancer Researchers from Israel have constructed a molecular-size computer that is programmed to find signs of cancer cells, and when they are present, dispense DNA molecules designed to eradicate those cells. |
Chemistry World April 5, 2007 Simon Hadlington |
Chemical Probe Seeks Out DNA Damage Researchers have developed a novel way to detect damage on DNA. The finding could open the way to a new toolkit of molecular probes to investigate the impact of chemical modifications on DNA, potentially providing insights into the way that mutations in DNA can result in cancers. |
Technology Research News May 21, 2003 |
DNA sensor changes color University of Rochester researchers have designed a simple, inexpensive sensor that can detect specific sequences of DNA on-the-fly. |
The Motley Fool November 17, 2006 Jack Uldrich |
Neanderthal DNA Enlightens Investors Investors, the superb performance of 454's gene sequencing equipment on such a difficult and important project bodes well for its future prospects. |
Chemistry World June 18, 2009 Lewis Brindley |
Chemical speed-dating even faster Researchers in the US have adapted a DNA amplification technique to develop a simpler way to rapidly screen chemical reactions. |
Chemistry World February 4, 2011 Holly Sheahan |
Crime scene DNA testing on the move A microfluidic chip that can come up with a DNA profile in less than three hours has been designed by US scientists for use at crime scenes. |
Chemistry World October 14, 2011 James Mitchell Crow |
Twist in the tale to improve gene therapy New insights into the physical properties of different forms of DNA could help to improve gene therapy, chemists in Spain and India say. |
Wired November 2002 David Ewing Duncan |
DNA as Destiny DNA is the book of life. It's also the book of death. In the future we'll all be read cover to cover. Here's what it's like to take the world's first top-to-bottom gene scan. |
PC World February 1, 2002 Kuriko Miyake |
Olympus Unveils DNA Computer Rather than relying on a microprocessor, computer runs on reactions between fragments of DNA... |
Chemistry World April 25, 2006 Jon Evans |
DNA Sequencing Reaches the Space Age The smallest ever DNA sequencer, only 10cm in diameter, comprises a complex network of microscopic pumps, valves, heaters and electrophoresis channels, many of which were initially developed for use in a device to detect life on Mars. |
Technology Research News October 6, 2004 |
Chip spots DNA electrochemically A microelectrochemical method of reading DNA chips could be used in portable detectors. It could be use practically in two to five years, according to the researchers. |
Chemistry World April 16, 2014 Jennifer Newton |
DNA cube programmed for an exclusive reveal Scientists in Canada have made DNA cubes that are programmed to unzip and reveal molecules locked inside them in response to a carefully chosen trigger. |
Chemistry World January 15, 2014 Kirsty Muirhead |
Biomarkers leave gender clues at crime scene Scientists in the US have unveiled details of a colorimetric assay that could provide an initial indication of a suspect's gender during the on-scene stages of a forensic investigation. |
Chemistry World October 7, 2011 Sarah Farley |
Detecting diseases with DNA sensors DNA sensors detect pathogenic and genetic diseases by binding to target DNA strands that are related to the disease and giving a signal that shows how much of the DNA is present. |
Bio-IT World April 15, 2003 Amanda Wren |
Get into the Groove Scientists strike a chord with music based on the building blocks of DNA. |
Technology Research News August 25, 2004 |
DNA Copier Uses Little Power Today's laboratory DNA detectors require a lot of energy. Researchers have devised a method that copies the way DNA is replicated biologically in order to avoid the energy-intensive heating and cooling process. |
IEEE Spectrum August 2007 Simon A. Cole |
Double Helix Jeopardy DNA databases help solve crimes but some say they also aid and abet racial discrimination. Can there be a compromise between the desire for privacy and the need for crime control? |
Chemistry World July 4, 2008 Emma Davies |
Creating a Second Genetic Code Japanese researchers have made artificial DNA that acts like the real thing, even forming right-handed duplexes with complementary artificial strands. |
Bio-IT World March 8, 2005 Patricia Reilly |
Biomarkers: Trends and Potential Companies are centralizing biomarker research to help reduce spending. |
Technology Research News February 25, 2004 |
Nanowires spot DNA mutation Nanowire sensors could eventually be built into labs-on-a-chip that could be used for medical diagnostics and pathogen detection in the field, and for drug discovery. |
Chemistry World October 7, 2015 Matthew Gunther |
DNA repair research takes the 2015 chemistry Nobel The 2015 Nobel Prize in chemistry has been awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for unraveling how cells deal with DNA damage. |
PC Magazine July 13, 2005 John R. Quain |
DNA Printing Press A group of scientists believes it has an inexpensive nanoprinting technique that could lead to the mass production of DNA-based chips that could revolutionize disease detection. |
Wired February 25, 2008 Julie Sloane |
15th Anniversary: DNA-Customized Medicine Still Stuck in the Pipeline Gene scanning isn't yet standard practice. But over the past six years, medicine has been inching closer to prescriptions that are custom-matched to a patients' DNA. |
Chemistry World January 20, 2011 James Urquhart |
SNPs on display DNA origami and atomic force microscopy have been combined to reliably detect and image single nucleotide polymorphisms, the most common form of genetic variation in the human genome. |