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Chemistry World
October 14, 2008
Simon Hadlington |
Enzymes hit with double punch US chemists have made a small molecule that simultaneously blocks two key enzymes involved in the growth of cancer cells.   |
Chemistry World
August 2, 2011
Phillip Broadwith |
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids. |
Chemistry World
June 19, 2013
James Urquhart |
Goeey secret of naked mole rat's cancer resistance revealed The p16 gene provides naked mole rats with an early contact inhibition mechanism that causes cells to stop dividing at much lower densities, compared with mouse cells. Their cells secrete a very high molecular mass form of a molecule called hyaluronan. |
BusinessWeek
January 17, 2005
Catherine Arnst |
No Pain, Some Gain The 50 million Americans suffering from chronic pain got a little bit of good news in December. The Food & Drug Administration greenlighted two new medications that attack pain in completely novel ways. |
HHMI Bulletin
February 2012
Marc Wortman |
Where Does It Hurt? Researchers are getting to the molecular details of pain's circuitry to answer the question with real specificity. |
Chemistry World
October 9, 2006
Michael Gross |
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid. |
Chemistry World
July 2010 |
Column: In the pipeline Derek Lowe ponders the possibility of phosphatase inhibitors |
The Motley Fool
March 4, 2010
Brian Orelli |
A Painless Drug Deal Bristol-Myers licenses pain drug from Allergan. |
Salon.com
October 2, 2000
Lynn O'Dell |
Pain in the brain The good news? The hurt is all in your mind. The bad news? The hurt is all in your mind... |
Chemistry World
September 13, 2012
Ian Le Guillou |
Hope for autism treatments Two reports in Science over the past week point the way to potential treatments for some forms of autism. |
Chemistry World
March 16, 2014
Simon Hadlington |
Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long. |
Chemistry World
March 22, 2012
Ross McLaren |
Back to the future: old reactions to help the new Researchers from the US have delved into the history of organic chemistry to help chemists better predict the effect that functional groups will have on one another within a molecule. |
Chemistry World
October 12, 2015
Andy Extance |
'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say. |
American Family Physician
May 15, 2001
Allan Gottschalk & David S. Smith |
New Concepts in Acute Pain Therapy: Preemptive Analgesia Preemptive analgesia, an evolving clinical concept, involves the introduction of an analgesic regimen before the onset of noxious stimuli, with the goal of preventing sensitization of the nervous system to subsequent stimuli that could amplify pain... |
Chemistry World
February 21, 2013
David Bradley |
Copycat flags help aliens avoid mouse immune system Synthetic peptide flags added to therapeutic and diagnostic agents can trick the immune system into ignoring them, according to US researchers. |
American Family Physician
October 1, 2001
Karl E. Miller |
Challenges in Pain Management at the End of Life Effective pain management in the terminally ill patient requires an understanding of pain control strategies. Ongoing assessment of pain is crucial and can be accomplished using various forms and scales... |
Scientific American
January 2, 2006
JR Minkel |
T Cells for Brain Cells Some researchers claim that inducing a mild autoimmune reaction could actually protect the central nervous system from a spectrum of neurodegenerative conditions, from glaucoma and spinal cord injury to Parkinson's and Alzheimer's disease. |
Chemistry World
February 3, 2012
Simon Hadlington |
Toxic mushroom behind Chinese deaths unmasked Chinese scientists believe they have identified the toxic assassins responsible for the mysterious deaths of hundreds of people in one of the country's provinces over the past 30 years. |
American Journal of Nursing
December 2010
Baldridge & Andrasek |
Pain Assessment in People with Intellectual or Developmental Disabilities Nurses in all settings need to be knowledgeable about alternate pain assessment methods. |
Nurse Practitioner
May 2012
Hammersla & Kapustin |
Peripheral Neuropathy: Evidence-based treatment of a complex disorder Peripheral neuropathy is a common and often progressive condition frequently seen in primary care. The chronic pain associated with PN, or neuropathic pain, can significantly diminish patients' quality of life and be challenging to treat. |
American Family Physician
February 1, 2005
Maizels & McCarberg |
Antidepressants and Antiepileptic Drugs for Chronic Non-Cancer Pain The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels. |
American Family Physician
May 15, 2001 |
Pain Relief After Surgery How will my pain be managed?...How are pain medicines given after surgery?... What should I do to make sure I receive the best possible pain relief?... |
Chemistry World
January 10, 2013
Laura Howes |
Rotaxane mimics ribosome to spin out peptides The field of molecular machines has taken a new bio-inspired turn to assemble another molecule, in this case linking up individual amino acids into a peptide. |
Chemistry World
August 22, 2014
Tim Wogan |
Yeast turned into morphine and opioid biofactories Genetically modified yeast can synthesize morphine and semisynthetic opioid pharmaceuticals, researchers in the US have shown. |
Chemistry World
October 31, 2013
Derek Lowe |
Natural born chemists Organic chemists may not seem like a humble group. But we should be, because we are humiliated every hour of the day by what nature accomplishes through enzyme catalysis. |
