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HHMI Bulletin
Nov 2010
Sarah C.P. Williams |
A Study on Antibiotic Resistance Shows That Bacteria Aren't Just Out To Help Themselves Microbes that are resistant to the drug protect their weaker kin in the colony, HHMI researchers have found. The discovery upends traditional notions of antibiotic resistance and offers a target for new drugs against bacterial infections.   |
Chemistry World
April 27, 2011
Carol Stanier |
Drug cocktails greater than the sum of their parts Canadian scientists have shown that combining an antibiotic that is past its prime with other drugs can give it a new lease of life. |
AskMen.com
Harold Russell |
The Lowdown On Superbugs The overuse and misuse of antibiotics has led to the development of resistant strains of bacteria, commonly referred to as superbugs. |
Chemistry World
December 15, 2015
Michaela Muehlberg |
Bacterial identification gets a culture shock Scientists in the UK have developed a new tool to distinguish bacterial strains from each other. |
Chemistry World
January 8, 2015
Matthew Gunther |
New antibiotic could treat infection while dodging resistance problems A new antibiotic that can kill life-threatening bacteria -- without them appearing to be able to develop resistance to the drug -- has been discovered by a team of scientists. |
IEEE Spectrum
February 2009
Monica Heger |
Computer-Designed Drugs Could Thwart Antibiotic-Resistant Bacteria Researchers use computer algorithms to tweak enzymes that make antibiotics |
Scientific American
May 2009
Melinda Wenner |
Quiet Bacteria and Antibiotic Resistance Bacteria devoted to growth instead of "quorum sensing" communication could beat antibiotic resistance. |
Chemistry World
August 11, 2011
Hayley Birch |
'Dial a Molecule' Approach Controls Antibiotic Production Scientists have used genetic methods to control the chemical structures of pacidamycin antibiotics produced in bacteria. Their approach allows them to 'dial into' particular molecules, and to generate new pacidamycins. |
Chemistry World
July 15, 2010
Matt Wilkinson |
Biotechs plot path of least resistance Biopharmaceutical companies are moving into antibiotics, and filling the void left by big pharma. |
Chemistry World
November 5, 2013
Emma Stoye |
Copper signals warn bacteria of antibiotic assault Copper is known for its antimicrobial properties, but new research suggests that copper signalling within bacterial cells may also play an important role in antibiotic resistance. |
Chemistry World
April 4, 2007
John Bonner |
Antibiotic Combinations Tackle Resistance Using combinations of certain antimicrobial compounds can favor the growth of non-resistant strains of bacteria at the expense of resistant ones. The surprising finding may provide a general strategy to help eradicate strains of bacteria that are resistant to antibiotic therapy. |
Chemistry World
September 19, 2008
John Bonner |
Filling the antibiotic gap Resistance to currently available antibacterial drugs is causing growing concern among doctors who find themselves unable to treat common infections |
Chemistry World
April 3, 2008
Philip Ball |
Antibiotic-Eating Bacteria Found in Soil Scientists in the US have found that soil is full of bacteria that will feed and grow on antibiotics the very compounds created to kill them. |
Nutrition Action Healthletter
May 2000 |
Magic Bullets Under Siege ...Antibiotics---drugs that kill bacteria---account for much of our success in the war against infectious illness. But the miracle drugs of medicine are in danger... |
Chemistry World
February 22, 2010
Hayley Birch |
Soil switches on antibiotic genes in bacteria So-called 'cryptic' bacterial genes that preside over the production of medically important compounds can be switched on using environmental triggers, German scientists have shown. |
Chemistry World
December 4, 2009
Lewis Brindley |
Potent two-pronged antibiotic provides hope for future drugs A two-headed compound obtained from soil bacteria may hold the key to developing the next generation of antibiotics, researchers in the UK report. |
Science News
June 28, 2003
Ben Harder |
McDonald's Cutback in Antibiotics Use Could Reduce Drug-Resistant Bacteria The fast-food chain McDonald's announced on June 19 that it will stop its farms under contract from feeding chicken, cattle, and pigs certain antibiotics intended to accelerate the animals' growth. That step might slow or reverse the rise of antibiotic-resistant bacteria that can infect people. |
Bio-IT World
January 21, 2005
Mark D. Uehling |
How to Find a New TB Drug Scientists at Johnson & Johnson (JNJ) have announced the first novel class of antibiotics in 40 years. The diarylquinolines, as the new compounds will be known, could offer shorter treatment regimens and be a precise weapon against tuberculosis. |
Chemistry World
September 11, 2013
Andria Nicodemou |
Bacteria incriminated by their odor Researchers in Taiwan and the US have developed a device that uses the volatile organic compounds released by bacteria to identify the bacteria as they are cultured. |
Chemistry World
January 10, 2010
Simon Hadlington |
Antibiotic decay products reverse resistance In a colony of bacteria living in the presence of an antibiotic in natural environments, individuals that are sensitive to the antibiotic can co-exist with those that are resistant, whereas logic would dictate that only resistant bacteria should survive. |
Chemistry World
June 28, 2013
Emma Stoye |
Antibiotic killing mechanism debate continues Antibiotics can kill bacteria without the need for reactive oxygen species. That's the claim of new research, which has added new evidence into the emerging debate over how antibiotics exert their lethal effects. |
Fast Company
May 2009
Elizabeth Svoboda |
Biotechs Wage War on Superbugs With antibiotic resistance on the rise, three biotechs are developing new ways to wage war on superbugs. |
American Family Physician
October 1, 2006 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics always work?... What is bacterial resistance?... What can I do to help myself?... etc. |
Chemistry World
September 12, 2006
Mark Peplow |
Bacteria Silenced by Conversation Stoppers Molecules that interrupt the chemical conversations of bacterial communities are showing early promise in beating the bugs. |
Chemistry World
March 6, 2013
Derek Lowe |
New antibiotics: what's the hold up? Money's a factor that could be adjusted by regulatory agencies, governments, and foundations. But no amount of cash will keep resistant bacteria from being the hard targets they are. |
Chemistry World
May 6, 2014
Andy Extance |
WHO raises alarm on deadly bacteria The World Health Organization has warned antibiotic resistant bacteria could bring a nightmarish future, where seemingly trivial scrapes turn lethal, and currently routine operations become too risky to contemplate. |
American Family Physician
December 15, 2000 |
Antibiotics: When They Can and Can't Help Antibiotics are strong medicines that can stop some infections and save lives. When they aren't used the right way, antibiotics can cause more harm than good. You can protect yourself and your family by knowing when you should use antibiotics and when you should avoid them... |
Chemistry World
February 12, 2015
Dinsa Sachan |
Target ignorance to tackle resistance After the discovery of the New Delhi metallo-beta-lactamase-1 (NDM-1) gene, which renders some bacteria resistant to most antibiotics, India has attracted global criticism for not being able to contain antibiotic resistance. |
Wired
September 25, 2007 |
Three Smart Things You Should Know About Bacteria The benefits of bacteria. |
Chemistry World
October 8, 2013
David Bradley |
3D printing bacteria Jason Shear and colleagues at the University of Texas, US, have developed a 3D printing technique that lets them 'construct' defined bacterial communities so that short-range chemical communications and physical interactions between bacteria can be investigated more systematically than ever before. |
Wired
May 22, 2009
Erin Biba |
New Germ Busters Outwit Antibiotic-Resistant Bacteria Researchers are testing new bug-killers that bypass the molecular pathways used by old-school antibiotics. |
Chemistry World
August 6, 2007
Tom Westgate |
Unique Antibiotic Beats Superbugs' Resistance The discovery of how a unique antibiotic kills its targets has uncovered a new way to tackle resistant superbugs. A team of chemists and structural biologists have studied how the natural antibiotic lactivicin interacts with a crucial bacterial protein. |
Chemistry World
February 22, 2011
Amaya Camara-Campos |
Repairing faulty genes Israeli scientists have developed compounds that could be better treatments for genetic diseases than current drugs. |
Chemistry World
March 13, 2013
Ned Stafford |
Antibiotic resistance is a 'ticking time bomb' Global research efforts to develop new antibiotics need to be accelerated urgently, the UK government's chief medical officer has warned. She adds that that new drugs are desperately needed to fight the 'catastrophic threat' of growing antimicrobial resistance. |
Chemistry World
January 30, 2015
Rebecca Trager |
Billion dollar package unveiled to fight antibiotic resistance President Obama has made a huge investment in the fight against antibiotic resistant bacteria |
Chemistry World
February 6, 2013
Harriet Brewerton |
Diagnosing bacterial growth Antibiotics are used regularly for treating bacterial infections, but there is currently no quick and simple test to determine the most effective type or dose of antibiotic for a specific patient infection. |
Chemistry World
May 12, 2011
Mike Brown |
Sugars recruited in fight against persistent infections Adding sugar to antibiotics can boost their effectiveness and prevent recurrent and chronic infections, according to researchers in the US. |
Chemistry World
May 29, 2014
Carla Pegoraro |
Dual warhead kills and disarms bacteria A compound that kills bacteria and cleaves their DNA to prevent them passing on drug-resistant genes has been designed by researchers in India. |
Chemistry World
August 27, 2014
Hayley Simon |
Ionic liquids join battle against antibiotic resistance US researchers have used ionic liquids -- organic salts that are liquid at room temperature -- to disrupt bacterial biofilms and deliver antibiotics through the skin's outer layer. |
Chemistry World
February 2, 2007
Jessica Ebert |
Bacterial Gene Generates Seaside Smell Researchers have identified a bacterial gene that is needed for the production of dimethyl sulfide, the climate-cooling gas responsible for the distinctive smell of the seaside. The discovery challenges the current hypothesis for the mechanism involved in the synthesis of DMS. |
Chemistry World
October 29, 2013
Harriet Brewerton |
Paper device spots antibiotic-resistant bacteria Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas. |
Mother Jones
December 2000
Edwin Dobb |
Growing Resistance Is agribusiness squandering one of medicine's most potent weapons? |
Chemistry World
September 24, 2015
Harriet Brewerton |
Antibiotics pit against bacterial biofilms Scientists in the US have designed a simple and inexpensive electrochemical device that monitors bacteria metabolites to gauge the effect of antibiotics. |
Chemistry World
June 30, 2011
Laura Howes |
Chemically evolved bacteria European scientists have created an Escherichia coli strain with a separate genome using chlorinated DNA. |
American Family Physician
January 15, 2004 |
Antibiotics: When They Can and Can't Help What are antibiotics?... Do antibiotics work against all infections?... What is "antibiotic resistance"?... Why should I worry about antibiotic resistance?... How do I know when I need antibiotics?... How should I take the antibiotics that my doctor prescribes?... etc. |
BusinessWeek
April 12, 2004
Catherine Arnst |
Killer Staph Is Hitting The Streets For the past 30 years, hospitals have been battling a mutant form called methicillin-resistant S. aureus (MRSA) that is resistant to penicillin-related antibiotics and is especially lethal. Now it's showing up in the general population. |
Scientific American
June 2008
Melinda Wenner |
Jeremy Nicholson's Gut Instincts: Researching Intestinal Bacteria The body and its intestinal flora produce chemicals with hidden health information, Jeremy Nicholson has found. Someday treating disease may mean treating those bacteria. |
Chemistry World
May 25, 2011
Sarah Houlton |
Bacteria could turn coffee waste into drugs Scientists at the University of Iowa, US, have discovered a new bacterium that feeds on caffeine. They claim it could synthesise various drug molecules and intermediates, and might even be used to decaffeinate coffee waste. |
American Family Physician
March 15, 2001 |
Avoiding Resistance to Antibiotics-- When Do I Need an Antibiotic? When bacteria are exposed to the same antibiotics, after a while the antibiotic can't fight the germs anymore... |
American Family Physician
September 15, 2006 |
When Antibiotics Can Help A consumer's guide: What are antibiotics?... How do antibiotics work?... What is antibiotic resistance?... How can I prevent antibiotic resistance?... |
