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Bio-IT World April 16, 2004 Malorye Branca	Finding the Perfect Fit Fragment-based drug discovery is unique and effective.
Chemistry World October 2008 Derek Lowe	Column: In the pipeline The author seeks a cure for 'compound bloat'
Chemistry World January 20, 2014 David Bradley	Molecular librarians create druglike collections Finding biologically active small molecules with pharmaceutical potential is a bittersweet process. Now, a new approach to building libraries of diverse alkaloid-type structures has been developed by US chemists.
Bio-IT World April 2007 Vicki Glaser	Software Solutions for Medicinal Chemistry Driven by advances in chemical synthesis, instrumentation, and high-throughput and high-content screening technology, medicinal chemistry's transition from an art to a science is benefiting from a wealth of new software products, spanning both bio- and cheminformatics.
Chemistry World September 29, 2015	Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make?
Bio-IT World April 15, 2003 Mark D. Uehling	Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials.
Chemistry World May 20, 2015 Katrina Kramer	Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.
Chemistry World October 2010	Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery
Chemistry World March 5, 2015 Emma Stoye	Forgotten synthetic PhD theses set to be given new lease of life A team of researchers have amassed a digital collection of more than 75,000 compounds from PhD theses that might otherwise have mouldered in obscurity.
Chemistry World December 2008	Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Chemistry World November 30, 2007 Lewis Brindley	Crystal Clear Structure Prediction One team of researchers has hit the jackpot by correctly predicting the crystal structures of four organic molecules in a competition organized by the University of Cambridge.
Bio-IT World February 10, 2003 Malorye Branca	Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic.
Chemistry World June 28, 2013 Phillip Broadwith	Data-sharing partnership for drug discovery AstraZeneca and Roche are pooling their data on compound properties to boost their chances of success in early stage drug development.
U.S. Banker December 2007 Lee Conrad	Institutional Investors Shun Investments in De Novos Institutional investors that have aggressively plowed money into de novo banks since 2002 have soured on this market since spring, according to market participants.
Chemistry World August 2009 Derek Lowe	Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder
Chemistry World June 2008 Sarah Houlton	Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success
Chemistry World April 2011	Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good.
Chemistry World June 23, 2015 Derek Lowe	Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example.
Chemistry World February 8, 2006 Jon Evans	To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space.
Chemistry World July 26, 2012 Derek Lowe	Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time.
Chemistry World October 28, 2014 Derek Lowe	Chemical space is big. Really big. We are not going to run out of interesting and useful structures, and the uses that they could be put to are probably also beyond our imagining. In chemical space, we really do have an effectively endless frontier.
U.S. Banker July 2010	Bring in the New: The Case for More Startup Banks De novo banks have a number of advantages established banks don't, namely the ability and proclivity to lend in the current shy-to-lend climate and easier adoption of current technology.
Chemistry World March 4, 2015 Philip Ball	Program ready to weed out tough drug leads A method for reliably predicting how well a candidate drug molecule will bind to its target receptor would allow libraries of molecules to be screened on the computer, without having to synthesize them all.
Pharmaceutical Executive February 1, 2006 Ron Feemster	Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets.
Chemistry World July 2008 Kevin Rogers	What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril
Bio-IT World October 10, 2003 Jeffrey Skolnick	Protein Structure Prediction in Drug Discovery Indications are that structure prediction can assist in the automated assignment of proteins to known pathways.
Reactive Reports Issue 58	ID Tags for Teenage Molecules One academic team has developed a logical technology that allows them to generate millions of unique tags to track sub-microscopic objects.
Chemistry World November 2011 Derek Lowe	Column: In the Pipeline In recent years there's another class of 'unknown' compounds that's become more prominent than ever: the ones you can buy from the chemical catalogues.
Chemistry World July 29, 2014 Derek Lowe	The crystal ball that can tell lies X-ray crystallography has long had a sort of halo around it as the 'ground truth' of molecular structure, so many chemists are surprised to learn how rife with error it can be.
Food Processing March 2009 Diane Toops	Kraft Foods Global Thinks Outside the Box with Bioactive Ingredients Kraft hires a pharmaceutical company to help it develop functional foods.
Inc. January 2006 Dan Ackman	Looking for Account Ability As with any start-up you work with, a de novo bank requires careful vetting.
The Motley Fool June 13, 2008 Brian Lawler	Novo Nordisk Bleeds a Little The pharmaceutical's hot streak ends as a vital study fizzles out.
Chemistry World April 2011	Column: In the Pipeline If you look over the whole pharmacopeia, you'll see there are a lot of compounds that got their start as natural products.
Chemistry World June 5, 2007 James Mitchell-Crow	Possible Pollutants Assessed in Minutes With Reach, the EU chemicals legislation, now in force, a computer system that predicts how chemicals biodegrade - or not - could help EU regulators spot persistent polluters.
Bio-IT World Dec 2006/Jan 2007 Giacomo Bastianelli	The Future of Predictive Biology Predictive biology, data and the integration of disparate research disciplines are key ingredients for the future of drug discovery research and healthcare.
Chemistry World July 19, 2010 Phillip Broadwith	Designing porous patterns Belgian chemists are finally getting to grips with how to control the way molecules arrange themselves at the solid-liquid interface.
Wired Erin Biba	Molecular Frameworks, the Building Blocks of All Life The world is complicated, but not as complicated as you might think. Most organic molecules derive from a few relatively simple architectures.
The Motley Fool June 18, 2010 Brian Orelli	Hot Dog! No Competition for Now Roche's diabetes pipeline drug is delayed.
Technology Research News November 3, 2004	Molecules Form Nano Containers Researchers have found a way to coax the self-assembly of minuscule multicompartment structures. The structures could eventually be used in drug delivery systems.
Chemistry World September 29, 2014 David Bradley	Pick and mix macromolecules New ways are discovered to piece together pi-functional molecular building blocks to make a wide range of macromolecules.
Chemistry World November 9, 2010 Andrew Turley	Company snapshot: Novo Nordisk As the results for the third quarter of this year roll in, one pharma major - Danish company Novo Nordisk - seems to have done better than most with its diabetes medicines.
Chemistry World November 18, 2014 Katrina Kramer	Molecules: the elements and the architecture of everything Molecules is a serious attempt to explain the world of chemical compounds to the reader without assuming previous science knowledge.
Inc. January 2006 Dan Ackman	A Bank, at Your Service The number of start-up banks is on the rise, and they're competing with the big boys by catering to business owners.
Chemistry World September 6, 2010 Phillip Broadwith	Are you sure that structure is right? UK chemists have developed a computer program that can work out how likely a chemical structure is to be correct, or identify the right structure from a range of possibilities.
Fast Company January 2002 George Anders	Roche's New Scientific Method How does a giant pharmaceutical company reckon with genomics technology? By making a fresh start in how it recruits its scientists, manages projects, and uses computers. Here's how the Roche Group is reinventing how it invents...
The Motley Fool September 30, 2008 Brian Lawler	Novo Nordisk Takes On All Comers Its diabetes franchise is about to get bigger.
Chemistry World May 20, 2015 Katrina Kramer	Molecules that amaze us For chemistry-savvy readers, the book is an enjoyable, easy-to-digest collection of fascinating molecules to dip in and out of.
The Motley Fool February 4, 2008 Brian Lawler	Best International Stock: Novo Nordisk A quick summary of Danish drugmaker Novo Nordisk, the world's number one manufacturer of diabetes medications.
The Motley Fool January 28, 2005 Stephen D. Simpson	An Understated Scandinavian The Danish pharmaceutical may not be quite cheap enough to be a true value, but investors looking for a solid growth stock should see what's new with Novo Nordisk.