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American Family Physician October 15, 2002 Zamorski & Albucher	What to Do When SSRIs Fail: Eight Strategies for Optimizing Treatment of Panic Disorder Effective management of panic disorder is a common challenge for family physicians. Selective serotonin reuptake inhibitors (SSRIs) are the drugs of choice for this condition because of their safety and efficacy. But not all patients have a favorable response to SSRI therapy.
American Family Physician August 1, 2006 Warner et al.	Antidepressant Discontinuation Syndrome Antidepressant discontinuation syndrome occurs in approximately 20% of patients after abrupt discontinuation of an antidepressant medication that was taken for at least six weeks.
American Family Physician May 15, 2004 Birrer & Vemuri	Depression in Later Life: A Diagnostic and Therapeutic Challenge Depression in elderly persons is widespread, often undiagnosed, and usually untreated. Because there is no reliable diagnostic test, a careful clinical evaluation is essential.
American Family Physician August 1, 2003 Stone et al.	Off-Label Applications for SSRIs Clinical experience supported by ongoing research continues to expand on the broad array of therapeutic applications for this class of medication.
American Family Physician June 15, 2002 Jeffrey L. Cummings	Guidelines for Managing Alzheimer's Disease: Part II. Treatment Once the clinical diagnosis of Alzheimer's disease has been made, a treatment plan must be developed. Patient symptoms and care needs change as Alzheimer's disease progresses.
American Family Physician November 15, 2000 Son & Kirchner	Depression in Children and Adolescents Depression among children and adolescents is common but frequently unrecognized. It affects 2 percent of prepubertal children and 5 to 8 percent of adolescents...
American Family Physician April 15, 2003 Dickerson et al.	Premenstrual Syndrome Premenstrual syndrome, a common cyclic disorder of young and middle-aged women, is characterized by emotional and physical symptoms that consistently occur during the luteal phase of the menstrual cycle.
American Family Physician October 1, 2002 Bhatia & Bhatia	Diagnosis and Treatment of Premenstrual Dysphoric Disorder From 2 to 10 percent of women of reproductive age have severe distress and dysfunction caused by premenstrual dysphoric disorder, a severe form of premenstrual syndrome. Current research implicates mechanisms of serotonin as relevant to etiology and treatment.
Nursing February 2010 Daniel A. Hussar	New Drugs 2010, PART 1 In this article, you'll learn about 16 new drugs.
American Family Physician October 1, 2000 Michael F. Gliatto, M.D.	Generalized Anxiety Disorder Patients with generalized anxiety disorder experience worry or anxiety and a number of physical and psychologic symptoms...
American Family Physician September 15, 2005 Cobb & Crichlow	STEPS: Duloxetine (Cymbalta) for Treatment of Major Depressive Disorder Duloxetine is safe and effective for the treatment of major depressive disorder. Because of its expense and the lack of data supporting its superiority over other antidepressants, it should be used as an alternative if other agents are ineffective or are not tolerated.
American Family Physician March 15, 2006 Shearer & Gordon	The Patient with Excessive Worry Worry is an effective short-term response to uncertainty that can become self-perpetuating with adverse long-term consequences. Evidence-based treatments for such disorders can assist family physicians in the management of this disorder.
American Family Physician February 15, 2005 Ham, Waters & Oliver	Treatment of Panic Disorder Panic disorder with or without agoraphobia occurs commonly in patients in primary care settings. This article assesses multiple evidence-based reviews of effective treatments for panic disorder.
Nursing March 2012 Daniel A. Hussar	New Drugs 2012: part I In this article, you'll learn about 11 recently approved drugs.
American Family Physician January 1, 2007 Shashi & Subhash Bhatia	Childhood and Adolescent Depression Safe and effective treatment of major depression in this age group requires accurate diagnosis, suicide risk assessment, and use of evidence-based therapies.
American Family Physician November 1, 2005 Steven H. Williams	Medications for Treating Alcohol Dependence Medications for treating alcohol dependence primarily have been adjunctive interventions, and only three medications -- disulfiram, naltrexone, and acamprosate -- are approved for this indication by the U.S. Food and Drug Administration.
Nursing June 2010 Daniel A. Hussar	New drugs 2010, part 2 In this article, you'll learn about 14 recently marketed new drugs.
American Family Physician August 15, 2001 Thomas P. Guck	Assessment and Treatment of Depression Following Myocardial Infarction Depression is an independent risk factor in the development of and mortality associated with cardiovascular disease in otherwise healthy persons...
American Family Physician September 15, 2000 Kim S. Griswold, M.D., M.P.H. & Linda F. Pessar, M.D.	Management of Bipolar Disorder A comprehensive management program, including collaboration between the patient's family physician and psychiatrist, should be implemented to optimize medical care...
American Family Physician December 1, 2005 Lawvere & Mahoney	St. John's Wort The herb has been found to be superior to placebo and equivalent to standard antidepressants for the treatment of mild to moderate depression. St. John's wort is generally well tolerated, although it may potentially reduce the effectiveness of several pharmaceutical drugs.
Nursing February 2009 Daniel A. Hussar	New Drugs 09: Part 1 Learn about 10 new drugs, including nebivolol HCl, the newest beta-adrenergic blocking agent for hypertension.
Nursing June 2011 Daniel A. Hussar	New Drugs 2011: Part 2 In this article, you'll learn about seven recently approved drugs, including: fingolimod hydrochloride, an oral drug indicated to treat patients with relapsing forms of multiple sclerosis.
American Family Physician February 1, 2005 Maizels & McCarberg	Antidepressants and Antiepileptic Drugs for Chronic Non-Cancer Pain The development of newer classes of antidepressants and second-generation antiepileptic drugs has created unprecedented opportunities for the treatment of chronic pain. These drugs modulate pain transmission by interacting with specific neurotransmitters and ion channels.
American Family Physician August 15, 2002 Ward & Zamorski	Benefits and Risks of Psychiatric Medications During Pregnancy Decisions regarding the use of psychiatric medications should be individualized, and the most important factor is usually the patient's level of functioning in the past when she was not taking medications.
Nurse Practitioner March 2012 Vanya Hamrin et al.	Evaluation and Management of Pediatric and Adolescent Depression The primary care setting is an appropriate venue for screening and identifying pediatric depression. Nurse practitioners can provide initial management or referral to psychiatric mental health professionals for evidence-based treatments.
American Family Physician August 15, 2000 Robert L. Phillips, Jr.	Depression and Sexual Desire Asking a depressed patient about libido and sexual function and tailoring treatment to minimize adverse effects on sexual function can significantly increase treatment compliance and improve the quality of the patient's life...
American Family Physician December 15, 2003 Bradley D. Grinage	Diagnosis and Management of Post-traumatic Stress Disorder Although PTSD is a debilitating anxiety disorder that may cause significant distress and increased use of health resources, the condition often goes undiagnosed. Treatment relies on a multidimensional approach, including supportive patient education, cognitive behavior therapy, and psychopharmacology.
Nursing April 2008 Kathryn Murphy	Shedding the burden of depression & anxiety Learn about types of depression and available treatments.
Nursing May 2012 Tim Blake	Three Medication Pathways for Bipolar Disorder No matter where you work, you're likely to care for patients with bipolar disorder, which affects about 2.6% of people age 18 and older per year.
Nurse Practitioner October 2011 Krauter & Cook	Pharmacogenetics and the pharmacological management of depression One CYP450 enzyme, CYP2D6, is responsible for the metabolism of 30% of all drugs including many antidepressants. Phenotypes of metabolizer status affect antidepressant treatment outcomes and adverse drug reactions.
Nurse Practitioner September 2010 Moloney & Cranwell-Bruce	Pharmacological Management of Migraine Headaches Migraine is one of the top 20 causes of disability worldwide, occurring in 17.6% of women and 5.7% of men
American Family Physician May 15, 2004 Smucny & Park	Clinical Inquiries From the Family Practice Inquiries Network: Which antidepressant is best to avoid sexual dysfunction?
American Family Physician August 15, 2000 Matthew Neff	Conference Highlights Investigational Alzheimer's Drug Improves Memory... Indoor Allergens Are Closely Linked with Allergic Disease and Asthma... Paroxetine Is Effective Treatment For Anxiety in Patients with GAD... Treatment with Citalopram Prevents Recurrent Depressive Episodes...
American Family Physician April 15, 2001 H. Russell Searight	Conduct Disorder: Diagnosis and Treatment in Primary Care Conduct disorder is a common childhood psychiatric problem that has an increased incidence in adolescence. The primary diagnostic features of conduct disorder include aggression, theft, vandalism, violations of rules and/or lying...
American Family Physician December 1, 2000 Sharon Scott Morey	Guidelines on Migraine Recommendations for Specific Prophylactic Drugs...
Nurse Practitioner February 2011 Jennifer M. Belavic	Annual Drug Update: 2010 in Review In 2010, the FDA approved several new drugs and new indications for use in primary care. From new therapies for adults with rheumatoid arthritis to a combination drug for benign prostatic hyperplasia, NPs need to be aware of the latest medications now available.
Nurse Practitioner February 2012 Jennifer M. Belavic	Annual drug update 2011 in review Many new medications were approved throughout 2011. This article will cover a variety of drugs that will be useful in nurse practitioner practice
American Family Physician November 15, 2003 Jones et al.	Common Problems in Patients Recovering from Chemical Dependency This article describes how to care for patients recovering from chemical dependency, including special concerns that arise during the treatment of common medical conditions, to avoid adverse outcomes or relapse into addiction.
American Family Physician September 1, 2000 Jennifer Travis Lange	Primary Care Treatment of Post-traumatic Stress Disorder Current treatment strategies combine patient education; pharmacologic interventions, such as selective serotonin reuptake inhibitors, trazodone and clonidine; and psychotherapy...
American Family Physician November 1, 2000 Searight, Burke & Rottnek	Adult ADHD: Evaluation and Treatment in Family Medicine Attention-deficit/hyperactivity disorder (ADHD) affects 30 to 50 percent of adults who had ADHD in childhood. Accurate diagnosis of ADHD in adults is challenging and requires attention to early development and symptoms of inattention, distractibility, impulsivity and emotional lability...
AskMen.com Jasper Anson	Anxiety Disorders In the United States alone, there are more than 40 million Americans who are suffering from some form of anxiety disorder. Here are some of the most common disorders and a few specific treatment options.
American Family Physician January 1, 2006 MODI Lowder	Medications for Migraine Prophylaxis Sufficient evidence and consensus exist to recommend propranolol, timolol, amitriptyline, divalproex, sodium valproate, and topiramate as first-line agents for migraine prevention.
Nurse Practitioner August 2011 Davis et al.	Supportive approaches for Alzheimer Disease Alzheimer disease accounts for almost 80% of all dementia diagnoses. Currently, more than 5 million Americans suffer from this debilitating illness, with the highest prevalence in the oldest age groups.
American Family Physician December 1, 2002 Aukerman et al.	Management of the Acute Migraine Headache As many as 30 million Americans have migraine headaches. The impact on patients and their families can be tremendous, and treatment of migraines can present diagnostic and therapeutic challenges for family physicians.
American Family Physician December 15, 2005 Hadley & Gaarder	Treatment of Irritable Bowel Syndrome Irritable bowel syndrome affects 10% to 15% of the U.S. population to some degree. Diagnosis is based on clinical signs and symptoms that include abdominal pain, bloating, constipation, and diarrhea.
American Family Physician June 1, 2003 Motsinger et al.	Use of Atypical Antipsychotic Drugs in Patients with Dementia Increasingly, atypical antipsychotic drugs are prescribed for elderly patients with symptoms of psychosis and behavioral disturbances. To minimize side effects, these medications should be started at low dosages that are increased incrementally.
American Family Physician February 1, 2006 Dana G. Carroll	Nonhormonal Therapies for Hot Flashes in Menopause Hot flash symptoms can significantly impact a woman's quality of life and should be addressed. Severity of the hot flashes, medical history, and concomitant medications should be considered in determining the best therapy for each patient.
American Family Physician July 1, 2000 Ted D. Epperly	Health Issues in Men: Part II. Common Psychosocial Disorders During screening examinations and, when appropriate, other health-related visits, family physicians should be alert for signs and symptoms of common psychosocial disorders in men. Health issues of concern include alcohol and substance abuse, domestic violence, midlife crisis and depression.
American Family Physician April 1, 2005 Toombs & Kral	Methadone Treatment for Pain States Recently, methadone has been used to manage cancer pain and other chronic pain states. Its unique pharmacokinetics and pharmacodynamics make methadone a valuable option, but physicians should be aware of possible side effects.
American Family Physician December 1, 2000 Norman J. Montalto	Updated Treatment for Influenza A and B The prevention of influenza is best accomplished with a broad-based immunization program...